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eClinicalMedicine – The Lancet Discovery Science

@eclinicalmed.bsky.social
388 followers 149 following 248 posts

Gold #OpenAccess clinical #medical journal, part of The Lancet Discovery Science, influencing clinical practice and strengthening health. IF: 12·8; CiteScore: 17·3. 🌐 www.thelancet.com/journals/eclinm/h…

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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 6h
Monoclonal gammopathy of undetermined significance ( #MGUS ) in Black individuals in Soweto, South Africa screened by mass spectrometry: PROMISE study Suggests Black South Africans represent a high-risk population with increased likelihood of having MGUS www.thelancet.com/journals/ecl...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 02/10/2026
Overnight metyrapone in mild autonomous #cortisol secretion: a single-centre, single-arm, phase 2 trial Overnight #metyrapone was well tolerated and associated with partial restoration of HPA axis balance and improved #sleep and mood www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 30/09/2026
Comorbid insomnia and sleep apnea (COMISA) and incident cardiovascular risk: a prospective analysis from the HypnoLaus cohort COMISA, but not OSA or insomnia alone, was associated with increased incident cardiovascular events www.thelancet.com/journals/ecl... #Insomnia #Sleep #CVD #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 28/09/2026
Global, regional, and national burden of #tetanus in 204 countries and territories, 1990–2023: analysis for the GBD Study 2023 Over the past 3 decades, global initiatives such as EPI and MNTE have led to a substantial reduction in the burden of tetanus www.thelancet.com/journals/ecl... #MedSky
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 28/09/2026
Published in @eclinicalmed.bsky.social Overnight metyrapone in mild autonomous cortisol secretion: a single-centre, single-arm, phase 2 trial www.thelancet.com/journals/ecl... #OpenAccess #MedSky #EndoSky
thelancet.com
Overnight metyrapone in mild autonomous cortisol secretion: a single-centre, single-arm, phase 2 trial
Overnight metyrapone was well tolerated and associated with partial restoration of HPA axis balance and improved sleep and mood. These findings support further controlled evaluation of metyrapone in M...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 25/09/2026
Vitamin B12 replacement strategies: a Brazilian delphi consensus Vitamin B12 replacement across all routes remains guided primarily by biochemical rather than clinical evidence www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 23/09/2026
📢NEW: September issue now online featuring #NoonanSyndrome, #Stroke, #HIV, #Spondyloarthritis, #Diabetes, #Sepsis, #Asthma, and more with our editorial on the rise of early-onset cancer …all available #free, #OpenAccess❗️ Read more here: www.thelancet.com/issue/S2589-... Attribution: Getty
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 23/09/2026
Published in @eclinicalmed.bsky.social The effect of #SGLT2 inhibitors, #GLP-1 receptor agonists, or #DPP-4 inhibitors on #stroke risk in type 2 #diabetes: a nationwide longitudinal cohort study in Sweden with contextualisation analysis www.thelancet.com/journals/ecl... #T2D #OpenAccess #EndoSky
thelancet.com
The effect of SGLT2 inhibitors, GLP-1 receptor agonists, or DPP-4 inhibitors on stroke risk in type 2 diabetes: a nationwide longitudinal cohort study in Sweden with contextualisation analysis
In this nationwide study, GLP-1RA were associated with reduced stroke risk, while SGLT2i and DPP-4i showed neutral effects. The overall direction of findings was consistent with evidence from RCT meta...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 21/09/2026
Our Senior Editor Jing Yuan will be at #WorldCancerCongress in Hong Kong, 24–26 Sept! 👋 If you’re attending, meet Jing and editors of other Lancet journals at our booth on 3F (A70). We’d love to hear about your research and chat about publishing with The Lancet Group #WCC2026
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 18/09/2026
Association between early bodyweight reduction and treatment outcomes in patients with #ObstructiveSleepApnoea and #obesity Early substantial weight reduction (≥15%) is associated with sustained improvements in #OSA and related cardiometabolic outcomes www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 16/09/2026
🚨The recording of our #free #Webinar "Transforming the Landscape of #GynaecologicalCancer: Advances in Prevention, Precision Surgery, and Innovative Systemic Therapies" is now available!🚨 Watch on-demand here: websurg.com/en/doi/wb01e... #MedSky @chrustrasbourg.bsky.social
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 15/09/2026
📢Check out our latest #News feature on the European Society of Cardiology (#ESC) 2026 Congress to read about some highlights from this year's event and learn more on the latest research and developments in cardiology: www.thelancet.com/journals/ecl... #ESC2026 #ESCCongress #Cardiology #MedSky
thelancet.com
European society of cardiology congress 2026
From robots on the concourse to an AI-assisted programme, the European Society of Cardiology's 2026 congress embedded Artificial Intelligence (AI), and its potential to advance cardiology at the heart...
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Greg Folkers @gregfolkers.bsky.social · 14/09/2026
EClinicalMedicine: Long-acting HIV pre-exposure prophylaxis adherence and discontinuation: a global systematic review and meta-analysis Xinyue Feng et al @eclinicalmed.bsky.social bit.ly/4xttQQj
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 14/09/2026
Intergenerational contact and depressive symptoms in midlife and older adults: analysis of 6 cohort studies across 33 countries The association between #intergenerational contact and #depressive symptoms among midlife and older adults is context dependent www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 10/09/2026
Impact of posttraumatic stress disorder on incident cardiovascular outcomes in women veterans: a retrospective longitudinal study PTSD is associated with a broad spectrum of CVD outcomes in women veterans www.thelancet.com/journals/ecl... #PTSD #CVD #Veterans #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 01/09/2026
🚨Our #free #Webinar "Transforming the Landscape of #GynaecologicalCancer: Advances in Prevention, Precision Surgery, and Innovative Systemic Therapies" is taking place this week!! Reminder to register now at: irc.ad/the-lancet-g... See you on Thursday!
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Reposted by eClinicalMedicine – The Lancet Discovery Science
The Lancet Medical Imaging & Theranostics @lancetimaging.bsky.social · 27/08/2026
📢 We’ve published our first issue! Read and download our inaugural issue here ➡️ www.thelancet.com/issue/S3117-... Thank you to our authors and reviewers for their valuable contributions ✨ As a gold open access journal, our content is free to read by everyone, always. #OA #MedSky #RadSky
Image ALT text: Representative images of individuals with different NMN BBB scores. The left column shows contrast enhanced MRI brain scans and the right column shows the fusion of the MRI scans and PET scans of these same individuals.  The top row corresponds to an individual with a NMN BBB score of 2 as minor parts of PET-positive volume show contrast enhancement on MRI. The bottom row corresponds to an individual with a NMN BBB score of 5 as the PET positive volume shows complete contrast enhancement on MRI. 
Copyright: The authors, Nathalie Albert and colleagues. Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 27/08/2026
🚨1 week to go until our #free #Webinar ! "Transforming the Landscape of #GynaecologicalCancer: Advances in Prevention, Precision Surgery, and Innovative Systemic Therapies" on Thursday September 3rd Don't miss out. Register now at: irc.ad/the-lancet-g...
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The Lancet @thelancet.com · 26/08/2026
🚨 There is still time to register for @eclinicalmed.bsky.social's webinar "Transforming the Landscape of #GynaecologicalCancer: Advances in Prevention, Precision Surgery, and Innovative Systemic Therapies". Register now: spkl.io/633237OAT3 Read the Series: spkl.io/633247OATO
Promotional card for the webinar "Transforming the Landscape of Gynaecological Cancer: Advances in Prevention, Precision Surgery, and Innovative Systemic Therapies".
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 26/08/2026
Efficacy and safety of sublingual cilostazol and dexborneol for the treatment of acute ischaemic #stroke: a phase 2 RCT Y-6 sublingual tablets (cilostazol and dexborneol) were safe and well tolerated. Large-scale phase 3 clinical trials are warranted www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 24/08/2026
📢NEW: August issue now online featuring #HepB, #MS, #BreastCancer, #Psoriasis, #COVID, #Psychosis, #MacularOedema, and more, with our editorial on #heatwaves and health system resilience …all available #free, #OpenAccess❗️ Read here: www.thelancet.com/issue/S2589-... Attribution: Getty #MedSky
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Kevin Ault @kevinault.bsky.social · 23/08/2026
Bonus add on to this thread. This meta analysis found hepatitis A vaccination to be 96 % ish effective in various clinical situations. #MedSky + #IDSky via @eclinicalmed.bsky.social www.thelancet.com/journals/ecl...
thelancet.com
Hepatitis A vaccination and its public-health impact in routine prevention and outbreak control: a systematic review and meta-analysis
Hepatitis A vaccination provides very high protection in pre-exposure settings. Post-exposure vaccination may also be effective, but confidence in this estimate is limited by very low-certainty eviden...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 22/08/2026
Published in @eclinicalmed.bsky.social The global cardiovascular-kidney-liver-metabolic burden from 1990 to 2023 www.thelancet.com/journals/ecl... #OpenAccess #MedSky #EndoSky #CardioSky #RenalSky #LiverSky
thelancet.com
The global cardiovascular-kidney-liver-metabolic burden from 1990 to 2023
Improvements in the global CKLM burden, driven by gains in CVD prevention, are offset by the rising burden of upstream CKLM drivers including obesity, T2D, CKD and MASLD. Population-focused strategies...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 21/08/2026
Have you signed up for our #free #Webinar yet? "Transforming the Landscape of #GynaecologicalCancer: Advances in Prevention, Precision Surgery, and Innovative Systemic Therapies" on Sept 3 Register here: irc.ad/the-lancet-g... Read the Series here: thelancet.com/series-do/gy...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 20/08/2026
Safety of routine antimicrobial prophylaxis for #surgery (SAPPHIRE): a prospective multicentre cohort study Increasing doses of antimicrobial prophylaxis did not improve surgical site #infection prevention, and side effect rates were higher than expected www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 18/08/2026
The impact of remote care on the quality of care of pregnant women with diabetes: a SRMA Remote care is a safe and effective alternative to usual care for #pregnant women with #diabetes, associated with reduced emergency c-sections and NICU admissions www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 14/08/2026
See image below for the programme for our #FREE #Webinar "Transforming the Landscape of #GynaecologicalCancer: Advances in Prevention, Precision Surgery, and Innovative Systemic Therapies" taking place on Thurs September 3rd! Register here: irc.ad/the-lancet-g... @chrustrasbourg.bsky.social
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 12/08/2026
RAS/MAPK pathway modulation with simvastatin in children with #NoonanSyndrome: a phase 3 RCT In children with NS, 12 months of #simvastatin did not result in significant improvements in the primary endpoint or in major outcomes of clinical relevance www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 10/08/2026
📢Reminder to register now for our free #Webinar "Transforming the Landscape of #GynaecologicalCancer: Advances in Prevention, Precision Surgery, and Innovative Systemic Therapies" taking place on Sept 3: irc.ad/the-lancet-g... Read the Series here: thelancet.com/series-do/gy...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 07/08/2026
#Artificialintelligence in cardiovascular care: a systematic review and meta-analysis of RCTs #AI shows potential benefits in intermediate process measures in #cardiovascular care but evidence of its effect on hard clinical outcomes remains limited www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 04/08/2026
📢Register now for our free #Webinar "Transforming the Landscape of #GynaecologicalCancer: Advances in Prevention, Precision Surgery, and Innovative Systemic Therapies" on Sept 3: irc.ad/the-lancet-g... Read the linked Series here: thelancet.com/series-do/gy... @chrustrasbourg.bsky.social
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Nuffield College Library @nuffieldlibrary.bsky.social · 04/08/2026
Sex differences in excess mortality during the COVID-19 pandemic: a longitudinal ecological analysis of 34 high-income countries doi.org/10.1016/j.ec... Paper in @eclinicalmed.bsky.social co-authored by @nuffieldcollege.bsky.social Senior Research Fellow @drjenndowd.bsky.social
doi.org
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 03/08/2026
Nationwide estimates of all-cause and cause-specific mortality among individuals with #GenderDysphoria in Sweden, 2001–2023: a cohort study Highlights persistent health inequities and the need for targeted public health interventions in TGD populations www.thelancet.com/journals/ecl... #MedSky
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 01/08/2026
Published in @eclinicalmed.bsky.social Cardiovascular outcomes and mortality risk at diagnosis of type 2 diabetes in older adults: a retrospective population-based study using health records from Spain www.thelancet.com/journals/ecl... #CVD #T2D #OpenAccess #MedSky #EndoSky #CardioSky
thelancet.com
Cardiovascular outcomes and mortality risk at diagnosis of type 2 diabetes in older adults: a retrospective population-based study using health records from Spain
Diabetes-associated relative excess risks for cardiovascular outcomes and mortality differed by age at first recorded type 2 diabetes diagnosis, with lower relative excess risks among those diagnosed ...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 31/07/2026
Health-related quality of life after risk-reducing #hysterectomy (PRESCORES): a cross-sectional study Health-related quality-of-life in women with #LynchSyndrome is likely to be lower following RRH in younger, pre-menopausal women www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 29/07/2026
Post-pandemic #RespiratoryInfections in children born during or before COVID-19 pandemic: a cohort study in Sweden Altered early-life microbial exposure due to pandemic-related restrictions may influence subsequent patterns of severe childhood infections www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 27/07/2026
Safety and efficacy of topical OCS-01 ophthalmic suspension for treatment of #DiabeticMacularEdema: a phase 2/3 trial In Stage 1 of this #trial, topical OCS-01 was well tolerated and improved visual acuity in patients with DME over the 12-week duration www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 24/07/2026
📢NEW: July issue now online featuring #GynaecologicalCancerCare, #Diabetes, #Menopause, #Sarcoma, #NSTEMI, #AAA, #Myeloma, #UTI, #PD and much more with our editorial on naming of diseases …all available #OpenAccess❗️ Read here: www.thelancet.com/issue/S2589-... Attribution: Getty #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 22/07/2026
Frailty status, clinical and functional outcomes in #CardiacAmyloidosis: a SRMA Patients with ATTR-CM and #frailty have higher mortality, poorer functional outcomes and reduced prescription of disease-modifying treatment compared to those without frailty www.thelancet.com/journals/ecl... #MedSky
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 21/07/2026
Published in @eclinicalmed.bsky.social Glycaemic biomarker trends across pre-war and wartime periods in Ukraine, 2021–2024: a repeated cross-sectional study www.thelancet.com/journals/ecl... #prediabetes #diabetes #OpenAccess #MedSky #EndoSky
thelancet.com
Glycaemic biomarker trends across pre-war and wartime periods in Ukraine, 2021–2024: a repeated cross-sectional study
The Ukrainian population experienced significant metabolic deterioration during the war. Rising HbA1c and the growing prevalence of prediabetes and diabetes, particularly among women and younger adult...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 20/07/2026
Patient and clinician acceptability of an integrated physiotherapy and nutrition intervention after ICU discharge Both patients and staff perceived the integrated physiotherapy and nutrition delivered in the ward setting as acceptable www.thelancet.com/journals/ecl...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 17/07/2026
📢 New #Podcast: Dr Ilaria Costantini joins Senior Editor Victoria Higgs to discuss her new SRMA which evaluated whether GLP-1 receptor agonists may reduce binge eating-related behaviours www.thelancet.com/audio-do/dr-... Read the Article here: www.thelancet.com/journals/ecl... #GLP1 #BingeEating
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Radiation Medicine Program @radmedpm.bsky.social · 16/07/2026
💡New in @eclinicalmed.bsky.social, former RMP Fellow Dr. Reinhardt Krcek, #RMPatPM Dr. Peter Chung, and colleagues report excellent long-term outcomes following preoperative radiotherapy and limb-sparing surgery for soft tissue sarcomas. 🔗: doi.org/10.1016/j.ec...
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The Lancet Diabetes & Endocrinology @thelancetendo.bsky.social · 16/07/2026
Published in @eclinicalmed.bsky.social The effectiveness of glucagon-like peptide-1 receptor agonists (#GLP-1RAs) on #binge #eating in patients with #obesity: a systematic review and meta-analysis www.thelancet.com/journals/ecl... #OpenAccess #MedSky #EndoSky #GastroSky
thelancet.com
The effectiveness of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on binge eating in patients with obesity: a systematic review and meta-analysis
GLP-1RAs reduced binge eating-related behaviours and emotional eating and increased cognitive or dietary restraint, though whether restraint is pathological is unclear. Given heterogeneity and high ri...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 15/07/2026
📢Check out our latest #News feature on the 12th European Academy of Neurology (EAN) Congress to read about some of the highlights from this year's event and learn more on the latest research and developments in #neurology: www.thelancet.com/journals/ecl... #EAN2026 #EANeurology #MedSky
thelancet.com
12th European Academy of Neurology (EAN) Congress
The 12th European Academy of Neurology (EAN) Congress took place in Geneva, Switzerland, from June 27 to 30, 2026. The event brought together more than 9700 participants from 124 countries, including ...
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Hospital del Mar Research Institute @researchmar.bsky.social · 14/07/2026
🧸Did you know that childhood trauma can also affect physical health? 🌊A study by @researchmar.bsky.social #HMRIB found that childhood trauma increases the risk of developing physical illnesses in adulthood by 1.57 times. 🔬Published in @eclinicalmed.bsky.social  📖 www.researchmar.net/news/842
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 13/07/2026
Predictors of early cancer burden in CDH1 pathogenic variant carriers: a single-centre cohort study Endoscopic surveillance using systematic biopsies reliably estimates #SignetRingCellCarcinoma burden on gastrectomy in #HereditaryDiffuseGastricCancer www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 09/07/2026
Efficacy of a hybrid psychoeducational and skills-based therapy (Trauma PORTAL) for adults with PTSD related to childhood interpersonal trauma: a parallel-group RCT Trauma PORTAL reduced #PTSD symptoms more than treatment as usual www.thelancet.com/journals/ecl... #MedSky
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 07/07/2026
📢Check out our latest #News feature on the #ESMO Gynaecological Cancers Congress 2026 to read about some of the highlights from this year's event and learn more on the latest research and developments in #GynaecologicalCancers: www.thelancet.com/journals/ecl... #ESMOGynae26 #ESMOGynae
thelancet.com
ESMO gynaecological cancers congress 2026
The European Society for Medical Oncology (ESMO) Gynaecological Cancers Congress 2026 took place on June 17–19 in Copenhagen, Denmark, and online. Bringing together more than 1270 delegates from 70+ c...
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eClinicalMedicine – The Lancet Discovery Science @eclinicalmed.bsky.social · 03/07/2026
Sociodemographic and gender affirmation factors associated with gender euphoria: a cohort study Results highlight the diversity of #gender euphoric experiences within trans communities and can be used to inform individualised supports www.thelancet.com/journals/ecl...
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