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Dylan Webster @dylanwebster.bsky.social · 17/02/2026

For R&D, this means screens can finally be designed around patient biology, not assay constraints. 🚀 #drugdiscovery #biotech #10xGenomics #singlecell

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Dylan Webster @dylanwebster.bsky.social · 17/02/2026

Zhu et al.: Scaled screens in primary CD4+ T cells by fixing at collection, ensuring results reflect biology, not batch effects. www.biorxiv.org/content/10.6...

biorxiv.org

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Dylan Webster @dylanwebster.bsky.social · 17/02/2026

Move over, cell lines. @10xgenomics.bsky.social Flex is also shifting functional genomics toward clinical cohorts by solving the sampling v. processing bottleneck. Through probe-based fixation, Flex enables a bank and batch workflow that eliminates noise in primary cells (example papers in thread).

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Dylan Webster @dylanwebster.bsky.social · 17/02/2026

Another one. ☝️ Last week: ProPer-seq. This week: VIPerturb-seq from the Satija Lab. Paper after paper is proving @10xgenomics.bsky.social Flex is the definitive engine for genome-scale perturbation screens. The new stats are wild: 🚀 440k cells/lane 🚀 50x throughput boost 🚀 65% more genes/cell

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Dylan Webster @dylanwebster.bsky.social · 20/10/2025

Awesome to see the power of the @10xgenomics.bsky.social Cloud Analysis (10xgenomics.com/cloud) back end come together with the accessibility of LLMs. Shout out to Evan Winget and Hayder Casey and our partners at @anthropic.com for making it happen. #singlecell #bioinformatics #ai #genomics

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Dylan Webster @dylanwebster.bsky.social · 19/02/2025

Check out what's next for 10x Genomics across #singlecell, #spatialbiology, and software!

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Dylan Webster @dylanwebster.bsky.social · 06/02/2025

#singlecell has come a long way. But we're also just getting started!

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Dylan Webster @dylanwebster.bsky.social · 07/01/2025

👀 Spotted in the wild! The official 10x Genomics account has landed on Bluesky.

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Reposted by Dylan Webster

Dylan Webster @dylanwebster.bsky.social · 07/12/2024

Want to help build software that enables researchers to answer biology’s hardest and most elusive questions? Do so as Senior Product Manager, Cloud Visualization Software at 10x Genomics! boards.greenhouse.io/10xgenomics/... #singlecell #spatialbiology #hiring #productmanagement #TechJobs

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Dylan Webster @dylanwebster.bsky.social · 13/12/2024

Kudos to the Xenium Explorer team at 10x Genomics for consistently upleveling what's possible out of the box for Xenium analysis! Check out our analysis page to see all Xenium analysis improvements! bit.ly/4flCNSu #spatialbiology #insitu #singlecellspatial #bioinformatics

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Dylan Webster @dylanwebster.bsky.social · 07/12/2024

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Reposted by Dylan Webster

Mixpanel @mixpanel.com · 26/11/2024

Emilie Schario says today's data tooling and LLMs make it so everyone can be a "data hire" 📊

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Dylan Webster @dylanwebster.bsky.social · 06/12/2024

Really good blog post! "... [T]he answer isn’t SQL expertise; it’s curiosity... Remember, a data hire isn't just a job title; it's a mindset." mixpanel.com/blog/emilie-...

mixpanel.com

Emilie Schario on making all your hires a ‘data hire’ | Signals & Stories

Insights for digital builders

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Reposted by Dylan Webster

Nav @naveed-ishaque.bsky.social · 29/11/2024

Check out our new tools for #SpatialTranscriptomics. It's called Sainsc: onlinelibrary.wiley.com/doi/10.1002/.... #Sainsc can map cell types in high resolution spatial transcriptomics data, without segmenting cells! It's light weight, fast, and easy to use: sainsc.readthedocs.io/tutorials/in...

onlinelibrary.wiley.com

Sainsc: A Computational Tool for Segmentation‐Free Analysis of In Situ Capture Data

Spatially resolved transcriptomics methods can now profile the entire transcriptome, at full organism scale with nanometre resolution. Analysis frameworks that can efficiently and intuitively process....

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Dylan Webster @dylanwebster.bsky.social · 22/11/2024

Extremely cool application of the Flex chemistry!

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Reposted by Dylan Webster

Dr. Jean Fan @jef.works · 22/11/2024

Check out our updated scatterbar package for visualizing proportional data across spatial coordinates like deconvolved cell types in #spatialtranscriptomics using stacked bar plots (alternative to scatterpies)! Preprint: www.biorxiv.org/content/10.1... Code: github.com/JEFworks-Lab... #dataviz

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Dylan Webster @dylanwebster.bsky.social · 18/11/2024

And now you can try the automated cell annotation directly in Cell Ranger 9! www.10xgenomics.com/support/soft... #singlecell #bioinformatics #genomics

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Dylan Webster @dylanwebster.bsky.social · 15/11/2024

Super excited about this cell typing collab between 10x Genomics and the Broad. broad.io/CAS-News Try it for free on cloud.10xgenomics.com/cloud-analysis and look out for more in the next Cell Ranger release coming imminently ;) (Let us know what you think!) #singlecell #bioinformatics #genomics

Infographic of the Cell Annotation Service

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Dylan Webster @dylanwebster.bsky.social · 13/10/2023

Did you know that 10x Genomics publishes intros, tutorials, and blogs that help navigate the journey to publish #SingleCell, Visium #SpatialTranscriptomics and Xenium #singlecellspatial data? Check out the Analysis Guides! www.10xgenomics.com/resources/an... #Genomics #Bioinformatics

Overview of the roadmap for 10x Genomics data analysis

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Dylan Webster @dylanwebster.bsky.social · 04/10/2023

You can also check out the public datasets that show this plexy: www.10xgenomics.com/resources/da...

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Dylan Webster @dylanwebster.bsky.social · 04/10/2023

There are 18,536 genes in the human probe set and 20,551 in the mouse probe set. This page also documents the Human Immune Cell Profiling Panel Antibody List for simultaneous readout of 35 proteins on Visium: www.10xgenomics.com/support/spat...

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Dylan Webster @dylanwebster.bsky.social · 04/10/2023

Hi Albert, this document has an overview of both the poly(A) capture approach for FF and the probe based approach for FFPE: www.10xgenomics.com/resources/do... This page has detailed documentation of the FFPE probe sets (click through to the individual pages: www.10xgenomics.com/support/spat...

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

Download the new Loupe here: www.10xgenomics.com/support/soft... Our goal is to accelerate your journey to experimental insights, and we hope you give Loupe 7 & and LoupeR a spin to see for yourself!

10xgenomics.com

Download Loupe Browser - Official 10x Genomics Support

Loupe Browser is a powerful visualization software that provides intuitive analysis functionality you need to explore your 10x Genomics data.

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

And check out how the redesigned Loupe user interface makes it simple to visualize the expression of your favorite genes!

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

The feature I’m most excited about: Finding target genes in your experiment just got easier with the new multi-sample differential expression in Loupe 7

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

Want to analyze Seurat data without code? Use the new 10x Genomics LoupeR package to move your data into the new Loupe 7. It sports a redesigned UI, and includes new features that put publication-ready figures just a few clicks away! #genomics #singlecell

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

Finally, review the recommendations for optimal assay performance. Either accept the recommendations or iterate as needed. At the end of the workflow, your panel is ready to be ordered and manufactured. Check it out for yourself! cloud.10xgenomics.com/xenium-panel...

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

Next, paste the list of genes you want to include. You can easily clean up the list to resolve any ambiguous gene names, etc. Then start building the design when you’re done.

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

Easily design 10x Genomics #singlecellspatial custom panels with the new #Xenium Panel Designer: Start with a pre-designed panel, or build a standalone custom panel (up to 480 plex). Design against curated references from CELLxGENE and GEO or bring your own references.

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

Use the per-gene localization gallery to fly through expression of each individual gene.

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

If you do H&E on the same section as your Xenium run, XE 1.2 also provides an intuitive workflow to align and overlay H&E in the Xenium coordinate space so you can see sub-cellular gene expression on top of your histopathological ground truth.

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

The Xenium Explorer screenshot represents exactly what can be visualized directly following a Xenium instrument run—where transcripts are decoded, cells are segmented, and graph-based clustering is computed as soon as the run is done with Xenium Onboard Analysis.

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Dylan Webster @dylanwebster.bsky.social · 02/10/2023

Check out the amazing preview dataset for the Xenium Mouse Tissue Atlassing Panel, showing expression of 379 genes in a an FFPE mouse pup (one day old, C57BL/6 strain)! Screenshot from Xenium Explorer 1.2. www.10xgenomics.com/resources/da... www.10xgenomics.com/support/soft...

Screenshot from Xenium Explorer 1.2 of the preview dataset of the Xenium Mouse Tissue Atlassing Panel, showing expression of 379 genes in a an FFPE mouse pup (one day old, C57BL/6 strain)

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