Bone Research - Inhibition of cyclin-dependent kinase 8 modulates chondrocyte transition to hypertrophy and provides in vivo protection against spontaneous osteoarthritis

Bone Research - Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies

npj Regenerative Medicine - CYR61 delivery promotes angiogenesis during bone fracture repair

Bone Research - Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies

New research from the Royal Veterinary College (RVC) has identified porcupine inhibition—a strategy that blocks a key bone-related signaling pathway (Wnt)—as a promising pharmacological treatment for severe sclerosteosis.

Bone Research - Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies