iiinova — where your digital self keeps evolving

Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

Dr Bilgili showed us the outcomes after OHTx divided by need of ECMO at 72 hours post surgery. ECMO need at 72 hours greatly worsens survival.

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

Dr Huang shows pre and post allocation change status change in immunosuppression and outcomes among multi-organ transplant. Super interesting data. @ishlt.bsky.social #ISHLT2025

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

Dr Elbert Heng shows amazing study on survival of patients with ACHD receiving OHTx vs multiorgan transplant alone. ❤️ and 🫁 carry the worse survival so far. @ishlt.bsky.social #ISHLT2025

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

Dr Paula Ramirez shows us their new predictive models to discriminate if ❤️ and kidney transplant is superior to kidney after ❤️. Beautiful work which can help change clinical practice at #ISHLT2025 @ishlt.bsky.social

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

Amazing work presented from Dr Topkara who developed a kidney risk score which predicts the risk for AKI/HD after ❤️ transplant! High AUC, higher than eGFR alone! #ISHLT2025 @ishlt.bsky.social

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

Dr Hussain showed us a single center experience of Fontain patients receiving ❤️ transplant. Should they get a liver as well? Seems like all 24 of them had recovery of the liver function after transplant without needing a a new liver. Great science at #ISHLT2025 @ishlt.bsky.social

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

Finally we talk about induction with Dr Barten. To induce or not to induce? This is the dilemma! And Dr Carboni showed us how AI can be implemented in helping us with HLA matching.

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

It’s AB0ut time we talk with Dr Aversa about AB0! Super interesting case of an 0 patient receiving nonA1 🫁 transplant with no signs of rejections. Incredible science showed at #ISHLT2025 @ishlt.bsky.social

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

Followed by Dr Guillaime Coutance guiding us through PRAs. Which antibodies should we look for and how to measure??? Dr Lyster showed us what to do with highly sensitised patients pre and post transplant. #ISHLT2025

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 30/04/2025

And last day at #ISHLT2025 we go through the consensus statement with Dr Annette Jackson. Amazing talk on the use of antibodies in transplant. @ishlt.bsky.social

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 28/04/2025

What is the role of MCS in PAH and cardiogenic shock? 1) patient selection 2) choose the RIGHT access 3) have an exit strategy in view 4) start PH therapies 5) consider transplant These are few of the points we discussed today with Dr Sommer @ishlt.bsky.social #ISHLT #PAH #PH

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 28/04/2025

What can you do when a patient with PH land in the ICU with Shock? Dr Mads Andersen walks us through Preload treatment Inotropes and its use Afterload for PH Important talk @ishlt.bsky.social #ISHLT2025 #PH

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 28/04/2025

And from the Right Ventricle- Right atria interaction we move to the complex relationship between heart - kidneys and lungs in PH with an amazing talk from Dr. Rosenkranz. #ISHLT2025 #PAH #PH @ishlt.bsky.social

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 28/04/2025

Today we dig deep in the pathophys of PH #ISHLT2025 with Dr Frances De Man on pressure loop of the RA. Super interesting discussion on what happens to myocites in the right atrium. @ishlt.bsky.social #PAH #PH

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 27/04/2025

Today @ishlt.bsky.social in Boston we talked about Pulmonary Hypertension. Here the main take-away from the Updates on the 7th World Symposium.

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Reposted by Dr Matteo Fabbri

Eric Topol @erictopol.bsky.social · 07/04/2025

In people with diabetes, GLP-1 and SGLT2i drugs were associated with less Alzheimer's disease and related dementias jamanetwork.com/journals/jam...

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 31/03/2025

Another study on the striking effect of sotatercept in PAH patients with elevated REVEAL score. Findings are not subtle at all! Trial stopped early with composite outcome of death, 🫁 transplant or hospitalization HR 0.24 (95%CI 0.13-0.43) www.nejm.org/doi/full/10....

nejm.org

Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death | NEJM

Sotatercept improves exercise capacity and delays the time to clinical worsening in patients with World Health Organization (WHO) functional class II or III pulmonary arterial hypertension. The eff...

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Reposted by Dr Matteo Fabbri

American College of Cardiology @accintouch.bsky.social · 29/03/2025

DAPA-TAVI: The #SGLT2 inhibitor dapagliflozin was superior to standard care alone in decreasing rates of all-cause mortality or worsening #HeartFailure in older adults w/ #vhdAS undergoing TAVI, resulting in a 28% relative risk ↘️. #ACC25 More: bit.ly/4cfLNsy #cvSurg #CardioSky #MedSky

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Reposted by Dr Matteo Fabbri

Eric Topol @erictopol.bsky.social · 24/03/2025

Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome. @naturemedicine.bsky.social

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 14/12/2024

I’ll diet on Monday… Chocolate chip cookies 🍪🍪🍪🍪

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Reposted by Dr Matteo Fabbri

International Society for Heart and Lung Transplantation (ISHLT) @ishlt.bsky.social · 13/12/2024

Happy #FridayThe13th - and if you're transplanting, fear not! This research group found no superstitious effect of Friday the 13ths or Full Moons on cardiac transplant outcomes, acuity, and volume. #JHLT #heartTx #cardiosky #transplantsky @uofpenn.bsky.social www.jhltonline.org/article/S105...

Goodnight Moon, The (not so) Mystical Effect of Folklore and Superstitions on Cardiac Transplantation
Do Friday the 13ths or Full Moons negatively impact heart transplants? Does volume increase on these "unlucky" days?

Slide shows study design and findings, which can be read at the link in the post.

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Reposted by Dr Matteo Fabbri

National Lipid Association @nationallipid.bsky.social · 10/12/2024

🚨 Big news in lipidology! 🚨 @newamsterdampharma.bsky.social's Phase 3 BROADWAY trial results for Obicetrapib are in: ✅ 33% LDL-C reduction at day 84 (vs placebo) ✅ 21% reduction in MACE after 1 year A promising advance for patients with #ASCVD & HeFH! #Cardiology #Lipidology

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Parham Eshtehardi MD @cardioobdoc.bsky.social · 04/12/2024

Simgle combined measure of hsCRP, LDL & Lp(a) among initially healthy U.S. women was predictive of incident CV events during a 30-yr period #CardioSky #MedSky #NEJM @drmarthagulati.bsky.social @erinmichos.bsky.social @michaeldshapiro.bsky.social @drlipid.bsky.social www.nejm.org/doi/full/10....

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 04/12/2024

Could not make it to AHA2024? Check out the HF highlights from @jcardfail.bsky.social. So great to be included in this. @robmentz.bsky.social @dranulala.bsky.social onlinejcf.com/article/S107...

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 02/12/2024

Echocardiogram is very important in diagnosing and managing pulmonary hypertension, but it could be very discrepant with the RHC especially if there not enough TR. Here you see the TR jet velocity of a young patient with hereditary PAH and next to it the RHC pressure curve in the PA.

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Reposted by Dr Matteo Fabbri

Parham Eshtehardi MD @cardioobdoc.bsky.social · 28/11/2024

Long-Term Aspirin vs Clopidogrel After Coronary Stenting by Bleeding Risk & Procedural Complexity 🦋 Clopidogrel monotherapy was associated with lower thrombotic & bleeding risks #CardioSky #MedSky @jama.com jamanetwork.com/journals/jam...

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 20/11/2024

A staple in every italian kitchen. The first thing we do in the morning and the last one at night;) ☕️ #coffee

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Dr Matteo Fabbri @drmatteofabbri.bsky.social · 17/11/2024

Hey bluesky, this is Osvaldo. He loves chasing anything that moves, eating, snuggling and purring. And if you look at him very closely, he has the cutest smile. 🐱❤️

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