Extended Data Fig. 1 Wasserstein distances between external, target, and deployment cohorts before and after covariate-shift adjustment across 20 diseases. Wasserstein distances were used to quantify covariate distribution differences between the external, target and deployment cohorts across 20 chronic disease datasets. Points connected by horizontal lines compare distances before and after covariate-shift adjustment. Abbreviations: HF, heart failure; MI, myocardial infarction; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; T2DM, type 2 diabetes mellitus; CKD, chronic kidney disease. Source data Extended Data Fig. 2 Weight distributions and normalized effective sample size for density-ratio weighting across all diseases in NHANES and SSACB. Box plots show the normalized density-ratio weights used to align the external and target training datasets with the calibration subset of the deployment population for each disease in a, NHANES and b, SSACB. Disease-specific sample sizes are provided in Supplementary Tables 11 and 32. Weights were normalized to have a mean of 1, and the y-axis is shown on a log10 scale. ESS/n denotes the normalized effective sample size, with higher values indicating more stable weights and smaller effective sample size loss. In each box plot, the centre line denotes the median, box bounds denote the first and third...

ALT: Lizzie McGuire's Dizzy Moment

People aged 60 and over face dangers to their health from exposure to heat at much lower temperatures than previously thought, research has found. Older adults will bear the brunt of increasingly frequent sustained spells of extreme heat globally as the world continues to warm up, according to a study in The Lancet Public Health. Heatwaves will leave huge and growing numbers of people worldwide of all ages suffering from uncompensable heat stress (UHS) – where the body loses the ability to cool itself – and thus at risk of serious damage to their health, including death. “Our results suggest accounting for age stratified vulnerability, intolerable heat will be experienced at much larger scales and for longer durations, affecting far more people than previously thought,” according to the study, which was led by health academics from Stanford University in California. Older adults are known to be more in danger because of the effects of very high temperatures. They sweat less, their hearts work harder in the heat and their blood vessels are less able to widen, limiting their capacity to stay cool. However, previous studies did not properly set out the different risks faced by younger people aged 15-39, middle-aged...

Human health and the health of the living world around us are so intertwined that you can’t talk about one without the other. As species disappear and ecosystems unravel, the risks to our food, mental health and even the air we breathe rise. Yet everyday choices can be good for our health and part of the solution for the planet. A sixth mass extinction The evidence suggests that species are disappearing at tens to hundreds of times the natural rate, leading many to describe a ‘sixth mass extinction’. Unlike past extinction events driven by volcanoes or meteor strikes, this one is largely caused by people: land clearing, intensive agriculture, pollution, climate change and invasive species. For the Northern Rivers, this is not an abstract global problem. We see it in damaged forests, stressed wildlife, more intense bushfires and floods, and declining marine life. The science is clear: there is no viable future for human health on a biologically impoverished planet. This ecological crisis is also a health crisis: our wellbeing depends on healthy, diverse ecosystems in more ways than we may realise. Nature: our life-support system Biodiversity, the variety of life on Earth, is our life-support system. Ecosystems provide food...

In some cases, vaccinated people can transmit measles, finds a review and meta-analysis of 33 reports published late last week in Expert Review of Vaccines. “Measles transmissions from vaccinated cases, although relatively uncommon, must be considered in public health investigations, as such transmissions can contribute to outbreaks,” wrote the authors, led by researchers at Public Health Ontario. A third of disease spreaders had received 2 doses It’s estimated that measles vaccines have prevented about 94 million deaths from 1974 to 2024. Prior to the vaccine’s introduction, measles caused 2.6 million deaths every year worldwide. The two-dose measles shot helped many countries eliminate the fast-spreading respiratory illness. But that trend has been shifting as vaccine hesitancy increases. This year, the United States has seen its most measles cases since 1991. For the review, the scientists examined peer-reviewed studies, as well as reports published outside of traditional publishing to understand if those vaccinated against measles might spread the illness to others. Some people can experience secondary vaccine failure, in which a natural, gradual loss of vaccine-created immunity is amplified because there’s little circulating virus to boost the immune response. Across all included reports, 70 out of 890 vaccinated people (7.9%) passed measles...

Scientists already know that cardiovascular problems in midlife can raise the risk of cognitive decline and dementia. This study is among the first to investigate how specific cardiovascular health factors may relate to cognitive aging across different ethnic groups. Researchers analyzed 402 people from San Antonio. Of the participants, 52% were Hispanic, and the rest were non-Hispanic white. Their mean age was 57.9, and 58.5% were women. The findings varied by ethnicity. Physical activity was particularly associated with slower cognitive decline among Hispanic participants, while lower fasting blood glucose levels were linked to slower cognitive decline among non-Hispanic white participants. "By improving cardiovascular health through modifiable lifestyle changes, there is a potential to meaningfully alleviate the public health burden of Alzheimer's disease and other dementias, particularly in high-risk populations," said Claudia Satizabal, PhD, associate professor in the Department of Population Health Sciences at UT Health San Antonio and its Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, where she leads the Population Neuroscience Core. Satizabal is co-senior author of the study with Chen-Pin Wang, PhD, associate professor-research in the Department of Population Health Sciences. The research, titled "Longitudinal association between midlife cardiovascular health and cognitive change in a bi-ethnic cohort,"...

A UK university spinout behind a rapid bacterial water testing kit is planning to launch live water quality maps, as scores of beachgoers report falling ill after swimming. Molendotech, a spinout from the University of Plymouth, sells a portable test that detects E coli and other bacteria in water and delivers results on the spot, without waiting for days to get laboratory results. Molendotech is now working on an app that will map water quality across Britain and the US, collating data from daily water tests with rain flow and tidal flows and using artificial intelligence to create predictive models. A launch is planned in the UK and US in October. There have been increasing calls for the government to step up water testing, amid numerous incidents of water pollution and sewage spills in recent years that have contaminated rivers and sea waters in popular locations. The campaign group Surfers Against Sewage has received 164 reports of sickness so far this year from beachgoers, mostly gastroenteritis but also ear and skin infections and other health problems. “Rivers are probably worse in the UK than in Europe,” said Simon Jackson, professor of environment and human health at Plymouth University and chief...

Fulfilling friendships and general close social relationships are strongly linked to excellent physical and mental health, finds a substantial global study published in the peer-reviewed Journal of Mental Health. Data from more than 200,000 adults shows good quality social connections and – to a lesser extent – positive family ties in childhood are associated with better perceptions of overall mental and physical health The research, representing one of the most comprehensive studies of its kind, spanned 22 countries including the UK, US, Australia, Argentina, Brazil, Germany, Spain, India, Japan, Egypt, Nigeria, South Africa, Mexico and others. The outcomes of the paper – carried out by Dr Veli Durmuş, from Kütahya Health Sciences University, in Türkiye – demonstrate the importance of social and family bonds. Dr Durmuş is now calling on policymakers to ensure health strategies recognise the influence of these emotional and social connections on mental and physical health. "I found that people who were more satisfied with their friendships and relationships also tended to report better mental and physical health," says Dr Durmuş, whose research specialism focuses on health management, health policy, the determinants of health, and health law. "These findings show why social connections should be considered an...

Wildland fire officials advise residents use a “Ready, Set, Go!” system of escalating preparation when wildfires are approaching, with the first two entailing increasing preparation such as assembling supplies, making plans and getting your home ready, and “go” meaning leaving. Ready: Includes creating a family disaster plan, having fire extinguishers, planning and practicing several evacuation routes, assembling an emergency supply kit with an extra in a vehicle as well as a list of emergency contacts, packing a bag with essentials needed for three days and appointing an out-of-area friend or relative as a point of contact. Set: Includes dressing appropriately with a dry bandana or particle mask,; ensuring emergency supplies and plenty of water are on hand, altering family and neighbors and, if time allows, preparing your residence by measures such as removing combustible materials from outside, turning off gas, moving furniture to the center of the room and closing doors and windows while leaving them unlocked. Go: Leave, preferably as early as possible. Don’t wait for a mandatory evacuation order if you feel unsafe. Go to a predetermined location such as a shelter, motel or a well-prepared neighbor or relative’s house and have several routes mapped out. Take your...

tl;dv has grown into a large AI meeting-notes platform, and its own public materials show why that matters: when you let a notetaker into every call, you are handing a vendor a map of your company's conversations. tl;dv is no longer a small productivity toy sitting at the edge of a browser. The German startup says it now has more than two million users and more than 21,000 customers, while its Google Workspace Marketplace listing shows more than 599,000 users for its Meet app. That's real reach. It also means a simple meeting tool has become part of the working memory of sales teams, recruiters, managers and founders who would never casually forward the same conversations to an outside inbox. Here's the thing. If you're using an AI notetaker, you're not just buying a transcript. You're letting software join the room, connect to your calendar, process names and timestamps, and turn conversation into searchable company data. tl;dv's own help center says users can auto-record Google Meet calls, including all meetings, internal meetings or external meetings, depending on their settings. That convenience is exactly why these tools spread so quickly. It is also why the security bar has to be higher...

Newswise — Harmful algal blooms are becoming more frequent and widespread as warming, eutrophication, agricultural runoff, aquaculture, and wastewater alter freshwater ecosystems. Once a bloom is visible, treatment can be costly, ineffective, or environmentally disruptive, making early warning essential. Yet many forecasting systems work at daily or weekly resolution, rely on fixed thresholds, or return only one predicted value without showing uncertainty. Deep-learning models may improve accuracy, but their decision processes often remain difficult to interpret, especially when drivers change rapidly before bloom onset. These gaps point to a need for in-depth research to develop high-frequency forecasting systems that quantify risk and explain when and why harmful algal blooms may emerge. The study was conducted by researchers from Beijing Institute of Technology, China University of Mining and Technology, and the Research Center for Eco-Environmental Sciences of the Chinese Academy of Sciences. Published (DOI: 10.1016/j.ese.2026.100733) online on July 21, 2026, in Environmental Science and Ecotechnology, the work introduces BloomNet as a multi-horizon forecasting system for harmful algal blooms. The model combines historical water-quality observations with environmental information available over the forecast window, producing hourly algal-density predictions for the next 24, 48, and 72 hours together with interpretable indicators of uncertainty and...

And the concern is warranted: Meta’s Ray-Ban Meta Glasses, for example, have been coined “pervert glasses” for recording people undressing, and the company is even being sued after a study revealed Meta’s subcontractors are viewing your most intimate moments. This is all culminating into a real privacy concern as not only is your right to privacy (or lack thereof) in the public realm coming into question, but so is how to stop what you do in public from getting stored on a company’s servers. “We are living in weird times,” Jim Waldo, a professor of computer science who teaches several technological privacy courses at Harvard, told Fortune. “The technology is changing. It’s the combination of the Meta Glasses with facial recognition, AI, and a number of other sorts of technologies that are all coming together and putting us in an environment that we just aren’t prepared to deal with yet.” The privacy concerns are real—from the suit to data collection, and even the social media content made with the tech has left people chalking up Meta Glasses as a form of surveillance. Even Meta’s Instagram has had to act: the platform disabled several accounts thanks to violations of content usage...

Obesity and mental health challenges have both reached epidemic levels, posing considerable public health concerns that increasingly affect young people.1,2 Roughly half of all mental disorder cases emerge during childhood and adolescence,3 with subclinical symptoms being even more prevalent. The Developmental Origins of Health and Disease framework suggests that periods of rapid physical growth are especially sensitive to external influences and insults.4 Given that accelerated growth and substantial psychosocial changes occur during adolescence, this developmental stage may represent a critical window for the emergence and consolidation of the relationship between obesity and mental health challenges.5 Therefore, it is essential to understand if and how these associations change with age in order to clarify how the dynamic relationship between mental health and weight development evolves across adolescence. So far, this has remained poorly understood. Previous research on mental health and physical growth has primarily focused on psychological distress, such as depression or anxiety, and the risk of obesity, with substantial evidence supporting their co-occurence.6,7,8,9,10 Two meta-analyses summarizing longitudinal studies in adolescents concluded that particularly females with depressive symptoms have an elevated risk of obesity over varying follow-up periods.9,10 This finding is corroborated by another systematic review.11 Anxiety, another indicator of psychological...

You have reached your maximum number of saved items. Remove items from your saved list to add more. The NSW government has identified little penguins and critically endangered regent honeyeaters as priority species for bird flu vaccination, after the state’s fifth case of the deadly virus was confirmed on Saturday in a greater crested tern found dead near Eden on the South Coast. At least 50 birds of the same species died in a mass mortality event in South Australia earlier this month. With increasing deaths and the detection of the virus in a “Typhoid Mary” superspreader species, attention is starting to shift from individual sick or dead birds to monitoring for mass die-offs and detecting shifts in the virus’s genetics. A Victorian plan to vaccinate 5000 little penguins on Phillip Island did not move fast enough, with news of a penguin dying from the disease breaking on Saturday. Advertisement The NSW government said plans to inoculate captive little penguins and regent honeyeaters in the state were on track but awaiting approval from the national Animal Health Committee. The government is working with organisations including Taronga Zoo, which breeds regent honeyeaters for wild release. Fewer than 400 exist in the...