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Alexander Holmes

@dralexholmes.bsky.social
175 followers 350 following 1 posts

Neuroscientist and Postdoc at FMRIB, University of Oxford Neuroimaging 🧠 Development 👶 Gradients 🌈 Genetics 🧬

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Reposted by Alexander Holmes
Marc L Seal @parkvillegeek.bsky.social · 01/09/2025
Toward Robust Neuroanatomical Normative Models: Influence of Sample Size and Covariates Distributions | bioRxiv www.biorxiv.org/content/10.1...
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Austin Benn @neurabenn.bsky.social · 06/06/2025
Precon_all is finally citeable! I’m relieved, pleased, thrilled and all other superlatives to present to you our preprint describing the inner workings of the precon_all pipeline for semi-automated non-human cortical surface reconstruction! www.biorxiv.org/content/10.1... 1/10
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Oxford University Centre for Integrative Neuroimaging (OxCIN) @oxcin.bsky.social · 03/06/2025
"I've always aspired to be a catalyst for change in my research field in Brazil, and OxCIN Global Scholars has made this goal more attainable." Kamilla Souza talks about her Global Scholar experience and her work with @neuroecologylab.bsky.social on dolphin brains: tinyurl.com/bdcva2zv
tinyurl.com
'A life-changing experience in my career' - reflections on OxCIN Global Scholars
We speak to OxCIN Global Scholars participant Kamilla Souza about her time on the scheme.
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Sidhant Chopra @sidchop.bsky.social · 12/05/2025
🧠💊New preprint differentiating antipsychotic medication vs. illness effects on cortical thickness in people w/ psychosis. Finding: People receiving placebo show prominent cortical thinning over 1st year of illness, whereas those receiving antipsychotics do not. 1/3 www.medrxiv.org/content/10.1...
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Imaging Neuroscience @imagingneurosci.bsky.social · 12/05/2025
New paper in Imaging Neuroscience by Isabella F. Orlando, Claire O’Callaghan, et al: Dopamine alters functional gradients in Parkinson’s disease doi.org/10.1162/imag...
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Reposted by Alexander Holmes
Marc L Seal @parkvillegeek.bsky.social · 24/04/2025
Attention and executive delays in early childhood: a meta-analysis of neurodevelopmental conditions | Molecular Psychiatry www.nature.com/articles/s41...
nature.com
Attention and executive delays in early childhood: a meta-analysis of neurodevelopmental conditions - Molecular Psychiatry
Molecular Psychiatry - Attention and executive delays in early childhood: a meta-analysis of neurodevelopmental conditions
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Alexander Holmes @dralexholmes.bsky.social · 17/04/2025
James is a great supervisor and doing a lot of really cool work right now - any neuro people that like tackling genuinely interesting research questions in a fantastic lab environment should defs apply
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The Transmitter @thetransmitter.bsky.social · 16/04/2025
The scientific community needs to develop processes to support, hire and retain researchers whose work sits between traditional fields of study, writes @avramholmes.bsky.social #neuroskyence www.thetransmitter.org/future-of-fm...
thetransmitter.org
fMRI must break out of its silo
We need to develop research programs that link phenomena across levels, from genes and molecules to cells, circuits, networks and behavior.
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Imaging Neuroscience @imagingneurosci.bsky.social · 26/03/2025
New paper in Imaging Neuroscience by Hui Wang, Emi Takahashi, et al: Imaging of developing human brains with ex vivo PSOCT and dMRI doi.org/10.1162/imag...
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Reposted by Alexander Holmes
Marc L Seal @parkvillegeek.bsky.social · 24/03/2025
The impact of heterogeneous spatial autocorrelation on comparisons of brain maps | bioRxiv www.biorxiv.org/content/10.1...
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Marc L Seal @parkvillegeek.bsky.social · 03/03/2025
The Good, the Bad, and the Ugly: Segmentation-Based Quality Control of Structural Magnetic Resonance Images | bioRxiv www.biorxiv.org/content/10.1...
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Marc L Seal @parkvillegeek.bsky.social · 27/02/2025
👏👏👏 Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | bioRxiv www.biorxiv.org/content/10.1...
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Reposted by Alexander Holmes
Imaging Neuroscience @imagingneurosci.bsky.social · 26/02/2025
New paper in Imaging Neuroscience by Jayson Jeganathan, Michael Breakspear, et al: Spurious correlations in surface-based functional brain imaging doi.org/10.1162/imag...
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Reposted by Alexander Holmes
Marc L Seal @parkvillegeek.bsky.social · 26/02/2025
The Generalizability of Cortical Area Parcellations Across Early Childhood | bioRxiv www.biorxiv.org/content/10.1...
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Reposted by Alexander Holmes
Marc L Seal @parkvillegeek.bsky.social · 23/02/2025
China Autism Brain Imaging Consortium: Charting Brain Growth in Chinese Children with Autism | bioRxiv www.biorxiv.org/content/10.1...
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Kevin Aquino 🧠🔑 @kevinaquino.bsky.social · 20/02/2025
I have had other papers pass this mile stone, but this one is special as it was my 1st, first-author paper, and was the output from my PhD many moons ago! @drbreaky.bsky.social @mschira.bsky.social
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James Pang @jchrispang.bsky.social · 03/02/2025
For my first-ever bluesky post, I'm really excited to share our new preprint "Geometric influences on the regional organization of the mammalian brain" with @alexfornito.bsky.social and a superstar 17-person team! (1/n) www.biorxiv.org/content/10.1...
biorxiv.org
Geometric influences on the regional organization of the mammalian brain
The mammalian brain is comprised of anatomically and functionally distinct regions. Substantial work over the past century has pursued the generation of ever-more accurate maps of regional boundaries,...
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Marc L Seal @parkvillegeek.bsky.social · 23/01/2025
Cognitive and psychiatric relevance of dynamic functional connectivity states in a large (N > 10,000) children population | Molecular Psychiatry www.nature.com/articles/s41...
nature.com
Cognitive and psychiatric relevance of dynamic functional connectivity states in a large (N > 10,000) children population - Molecular Psychiatry
Molecular Psychiatry - Cognitive and psychiatric relevance of dynamic functional connectivity states in a large (N > 10,000) children population
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Reposted by Alexander Holmes
Erynn Christensen (she/her) @drerynnchristensen.bsky.social · 28/12/2024
What a way to end the year! Brilliant work by @elvisha.bsky.social and the team. Proud to be part of a lab that is focused on championing these issues in neuroscience.
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Annie G. Bryant @anniegbryant.bsky.social · 27/12/2024
📣 First three years of my PhD have culminated in this work now published at PLoS Computational Biology! 🥳 We take a deep dive into all the many ways we can slice n dice fMRI dynamics to quantify biologically relevant properties 🧠🧮 doi.org/10.1371/jour...
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 22/12/2024
Spanning spatial scales with functional imaging in the human brain; initial experiences at 10.5 Tesla www.biorxiv.org/content/10.1101/202…
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Brandon Munn @bmunn.bsky.social · 18/12/2024
Hi BlueSky fam, for my first post and to celebrate our recent paper being physically published I thought I’d do a summary thread! This has been my most favourite (and toughest) work to date. Please help share around!! www.cell.com/cell/abstrac... (Reach out if you can’t access)
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DrBreaky @drbreaky.bsky.social · 18/12/2024
The Brain Connectivity Workshop 2025 will be held just before #OHBM2025 on the paradise that is Minjerribah (North Stradbroke Island) a one hour ferry ride from Brisbane Registration will open shortly (cost to be <$600 for travel registration & accomodation) so please plan your flights accordingly
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Todd Constable @toddc.bsky.social · 18/12/2024
Now that those #OHBM abstracts are done - think about submitting to this connectivity workshop. Stellar lineup of speakers is set! Register (and submit abstracts) here - medicine.yale.edu/mrrc/about/s... deadline is Jan 10, 2025.
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𝕤𝕡𝕒𝕔𝕖𝕔𝕒𝕥 𝕚𝕟 𝕤𝕡𝕒𝕔𝕖 @sugarkat.bsky.social · 15/12/2024
HBO has declined to renew “Sesame Street” for new episodes. The series that’s been teaching generations of little kids since 1969 now has no studio. Please consider donating to Sesame Workshop to ensure the residents of 123 Sesame Street are still around to teach kids of all needs and backgrounds.
sesameworkshop.org
Support Us - Sesame Workshop
Individual donors and partners can have a major impact. Join Sesame Workshop’s Mission to Help Kids Everywhere Grow Smarter, Stronger, and Kinder.
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Reposted by Alexander Holmes
Matt Wall @mattwall.bsky.social · 12/12/2024
New blog post! I figured out how to make some really nice visualisations of brain networks using Gephi, and wrote a tutorial on how to do it here: medium.com/@m.b.wall/ho...
medium.com
How to make super-fancy brain network plots: A tutorial with Gephi
This paper by Petri et al. from 2014 contains one of the most famous images in psychedelic science:
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Steve Smith @fmrib-steve.bsky.social · 06/12/2024
Imaging Neuroscience new-paper posts from 2023. At the end of December we'll post the much bigger 2024 montage (even Rocky had a montage).
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Altmetric @altmetric.com · 03/12/2024
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research. A Place of Joy.
‘A place of joy’: why scientists are joining the rush to Bluesky
Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.: https://www.nature.com/articles/d41586-024-03784-6
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Sylvain Baillet @sylvainbaillet.bsky.social · 03/12/2024
« By the time they die, nearly half of women [in the US] will have lost their uterus. » This is insane. www.nytimes.com/2024/12/02/h...
nytimes.com
So You’ve Had a Hysterectomy. Do You Know What Was Removed? (Gift Article)
Patients often are in the dark about which organs remain and which were removed — particularly the ovaries, which profoundly influence lifelong health.
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Todd Constable @toddc.bsky.social · 29/11/2024
Here's another sample of the amazing speaker lineup for Whistler Brain 2025. @drbreaky.bsky.social @anastasiayendiki.bsky.social Register here: medicine.yale.edu/mrrc/about/s... Abstract submission is open - get yours in!
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Rosanna Olsen @rosannaolsen.bsky.social · 29/11/2024
A great opportunity to share your 🧠 science and inspire a young learner! Each year, the OHBM Diversity and Inclusion committee helps organize educational sessions on brain mapping across the world with school aged children. Sign up below to learn more about how to get involved!
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Jonny Smallwood @themindwanders.bsky.social · 26/11/2024
Excited about this new paper in Elife where we show for the first time resting state patterns contain information about a participants states (e.g. their thoughts) as well as traits (e.g. personality). Led by the awesome @hardigirl.bsky.social postdoc in THINC Lab elifesciences.org/articles/93689
elifesciences.org
Macro-scale patterns in functional connectivity associated with ongoing thought patterns and dispositional traits
Interactions between attention systems and the default mode network are linked to individual differences in trait and state-level experience and cognition.
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Elvisha Dhamala @elvisha.bsky.social · 21/11/2024
Latest work led by Xihan Zhang looking at the cell-type underpinnings of the human functional cortical connectome is out now in Nature Neuro! 🧠 www.nature.com/articles/s41...
nature.com
The cell-type underpinnings of the human functional cortical connectome - Nature Neuroscience
Here Zhang et al. establish multiscale relationships that link postmortem cell-type distributions with the in vivo functional organization of the human cerebral cortex, as assessed through functional ...
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eLife @elife.bsky.social · 20/11/2024
Following the news that eLife will not receive an Impact Factor in 2025, we’ve shared an update on how our model is doing since we were first placed “on hold” by Web of Science, and what we’re up to now. Find out more. buff.ly/3ATRAFT
buff.ly
The eLife Model: An update on progress following changes in Web of Science indexing status
Following the decision that eLife will not receive an Impact Factor in 2025, we share an update on how our model is doing since we were first placed “on hold” by Web of Science, and what we’re up to…
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Stuart Oldham @stuartoldham.bsky.social · 19/11/2024
Some new work from myself, @alexfornito.bsky.social, and @garedaba.bsky.social where we investigate the performance of generative Network Models (GNMs) 🧠🌐🤖. A 🧵 (1/6) www.biorxiv.org/content/10.1...
biorxiv.org
Coming up short: generative network models fail to accurately capture long-range connectivity
Generative network models (GNMs) have been proposed to identify the mechanisms/constraints that shape the organisation of the connectome. These models most commonly parameterise the formation of inter...
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Kevin Mitchell @wiringthebrain.bsky.social · 18/11/2024
Large-scale exome sequencing identified 18 novel genes for neuroticism in 394,005 UK-based individuals #icanhazpdf? www.nature.com/articles/s41...
nature.com
Large-scale exome sequencing identified 18 novel genes for neuroticism in 394,005 UK-based individuals - Nature Human Behaviour
In 394,005 UK individuals with exome sequencing data, Wu et al. find 56 neuroticism-associated genes (18 novel) and quantify the heritability explained by rare coding variants, highlighting the associ...
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