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Dan MacGuigan

@dmacguig.bsky.social
1.7K followers 629 following 32 posts

DJM Computational Biology, LLC. Smithsonian NMNH Independent Contractor - bioinformatics, systematics, genomics, speciation, & hybridization - University of Rochester undergrad, Yale EEB PhD, University at Buffalo NSF PRFB. danjmac.weebly.com

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Reposted by Dan MacGuigan
Alt National Park Service @altnps.bsky.social · 18/09/2026
Reminder. 💚✊
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Allen Collins @agcollins.bsky.social · 13/09/2026
Our new paper on the distribution of the benthic ctenophore Vallicula integrates diverse observations (iNAT, literature, museum specimens, and eDNA metabarcodes) to show that Vallicula multiformis is circumtropical to subtropical. onlinelibrary.wiley.com/doi/10.1111/...
Global map with points of observations stemming from diverse sources. Shows a circumtropical to subtropical distribution.
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Dan MacGuigan @dmacguig.bsky.social · 08/09/2026
With fantastic coauthors @fishgenomes.bsky.social, @mtanichthys.bsky.social, @almeidasilvaf.bsky.social, Hannah Waterman, Jessie Pelosi, Nate Backenstose, and Sarah Chang
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Dan MacGuigan @dmacguig.bsky.social · 08/09/2026
New paper in Systematic Biology! We show how micro-synteny can help resolve a tricky fish #phylogenetic problem where traditional sequence-based analyses fall short. Genomes archive evolutionary history in more than just their basepairs. doi.org/10.1093/sysb... #fish #genomics #evolution
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Dan MacGuigan @dmacguig.bsky.social · 08/07/2026
Check out our new paper linking #genomics and #geology with #evolution in a group of freshwater #fish. Grateful to have played a small part in this exciting study led by @dkimfish.bsky.social , Dr. Maya Stokes, and @tjnear.bsky.social. doi.org/10.1093/evol...
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Dan MacGuigan @dmacguig.bsky.social · 02/07/2026
Working with mitogenomes for eDNA, phylogenetics, etc, but not sure what's available on GenBank? Maybe your study group has weird mitogenome features? Come explore with with my new GenBankMitoReview tool! github.com/dmacguigan/G... #DNA #bioinformatics #eDNA #GenBank
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Dan MacGuigan @dmacguig.bsky.social · 03/02/2026
Whoa, never thought I'd have research featured on Jeopardy!
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Dan MacGuigan @dmacguig.bsky.social · 03/02/2026
Whoa! Need to find a way to work that into my CV, haha!
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Dr. Solomon David @solomonrdavid.bsky.social · 02/02/2026
Here’s the @jeopardyofficial.bsky.social GAR question based on our team’s living fossil study (led by @chasedbrownstein.bsky.social @dmacguig.bsky.social)!
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Dan MacGuigan @dmacguig.bsky.social · 02/01/2026
GitHub repo for the PhenoDelimit package: github.com/dmacguigan/P...
github.com
GitHub - dmacguigan/PhenoDelimit: R package to create "STRUCTURE-esque" barplots and compare species delimitation models with multivariate phenotype data
R package to create "STRUCTURE-esque" barplots and compare species delimitation models with multivariate phenotype data - dmacguigan/PhenoDelimit
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Dan MacGuigan @dmacguig.bsky.social · 02/01/2026
With coauthors Adam Taylor, Ava Ghezelayagh, Julia Wood, Jeff Simmons, Jon M. Mollish, and @tjnear.bsky.social
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Dan MacGuigan @dmacguig.bsky.social · 02/01/2026
Check out our new paper! We debut the #R package PhenoDelimit, a simple #ML approach to morphological species delimitation without a priori lineage assignment. Plus we describe a new darter species, 𝘼𝙡𝙡𝙤𝙝𝙞𝙨𝙩𝙞𝙪𝙢 𝙖𝙣𝙖𝙨, endemic to the Duck River system in TN. doi.org/10.1093/sysb... #fish #genomics
doi.org
Genomic and Phenotypic Delimitation of Species in a Temperate Aquatic Biodiversity Hotspot
Abstract. Biologists have relied on morphological characteristics to identify, define, and formally describe species for the past 250 years. The advent of
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Pia Schwarz @pfschwarz.bsky.social · 26/12/2025
I am very excited to share our new paper with my amazing co-authors and mentors @dmacguig.bsky.social @fishgenomes.bsky.social @tjnear.bsky.social . We investigate a secondary contact zone in #darters. track.smtpsendmail.com/9032119/c?p=...
track.smtpsendmail.com
Mosaic tri-lineage secondary contact shapes diverse genomic outcomes in darters
Abstract. Speciation does not always lead to complete reproductive isolation, which can result in hybrid zones with gene flow. In freshwater fishes, second
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Dan MacGuigan @dmacguig.bsky.social · 27/12/2025
Huge congrats to my mentee @pfschwarz.bsky.social on her first first-author paper! Three-way secondary contact and mosaic hybridization in darters. Plus a bonus comparison of ddRAD vs lcWGS. @fishgenomes.bsky.social @tjnear.bsky.social #fish #evolution #genomics doi.org/10.1093/evol...
Map and phylogeny of complex hybrid zone between two darter speciesComparison of Fst estimates from ddRAD vs lcWGS
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Joel Corush @jcorush.bsky.social · 04/12/2025
I'm recruiting a Ph.D. student for Fall 2026. Interested in comparative studies and trait evolution in fishes? Send me an email with a CV and research interests. Please take a look at my website (jcorush.github.io ) for more information about my research. #hybridization #minnows #mudskippers
jcorush.github.io
Corush Lab
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Aaron Rupar @atrupar.com · 30/09/2025
This is one of the most demented things Trump has posted
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Dan MacGuigan @dmacguig.bsky.social · 22/09/2025
With my fantastic co-authors @fishgenomes.bsky.social, Hannah Waterman, Jessie Pelosi, Nate Backenstose, Sarah Chang, @mtanichthys.bsky.social, and @almeidasilvaf.bsky.social
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Dan MacGuigan @dmacguig.bsky.social · 22/09/2025
Check out our new preprint! We compare sequence versus synteny approaches for resolving a challenging #phylogenetic problem. In this case, synteny is far more informative! Also includes the first chromosome-level #genome for the enigmatic #fish family Gyrinocheilidae. doi.org/10.1101/2025...
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iNaturalist @inaturalist.bsky.social · 14/05/2025
Just a pair of Gold-spotted Mudskippers (Periophthalmus chrysospilos) doing their semiaquatic thing. 📷 nitiroj_boonsai on iNaturalist 📍 Thailand 🔗: www.inaturalist.org/observations... #ObservationOfTheDay
Two long grayish-colored fish with orange fins and orange spots along their body rest on what looks like a mossy rock.
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Dan Garisto @dangaristo.bsky.social · 23/04/2025
In addition to the terminations of existing awards, new NSF grants are still stopped completely since DOGE was granted access to systems a week ago. Last Thursday, an agency spokesperson said "NSF continues to issue awards." That does not appear to be the case.
Graph of NSF awards. Compares April 2024 to April 2025, which levels off.
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Dan MacGuigan @dmacguig.bsky.social · 11/04/2025
Thank you @sse-evolution.bsky.social! Thrilled to have our paper recognized.
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Madeline Ostrander @madelinevo.bsky.social · 27/02/2025
A source just told me over the phone that layoffs are happening right now at NOAA. Axios is also reporting this. www.axios.com/2025/02/27/l...
axios.com
Layoffs hit federal climate, weather agency NOAA
The cuts could affect NOAA's weather forecasts, climate research and other functions.
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Alejandro Alvarez @aletakesphotos.bsky.social · 27/02/2025
USAID staff have two days to clean out their offices at the agency’s former headquarters in DC. People are gathering on the sidewalk in the rain to show their support, applauding workers as they pass by.
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Bruno J. Navarro @brunojnavarro.bsky.social · 05/02/2025
“They apparently just sort of walked past security and said: ‘Get out of my way,’ and they’re looking for access for the IT systems, as they have in other agencies,” said a former Noaa official. “They will have access to the entire computer system, a lot of which is confidential information.”
theguardian.com
Doge staffers enter Noaa headquarters and incite reports of cuts and threats
Members reportedly sought access to IT systems at agency that Project 2025 has called ‘harmful to US prosperity’
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Dan MacGuigan @dmacguig.bsky.social · 03/01/2025
Very grateful to have contributed to this important research!
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Tom Near @tjnear.bsky.social · 03/01/2025
1/4New from the #NearLab, genomics and morphology demonstrate the famous Snail Darter, Percina tanasi, the little fish that swam to the United States Supreme Court is not a distinct species... Open access at Current Biology www.cell.com/current-biol...
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Dr Angel Borja @drangelborja.bsky.social · 29/11/2024
Marine institutes and University departments doing marine research, join the conversation here. Only official organisations go.bsky.app/K7HxGsK
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Dan MacGuigan @dmacguig.bsky.social · 24/11/2024
Thanks!
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David Shiffman, Ph.D. 🦈 @whysharksmatter.bsky.social · 16/11/2024
I’m working on a starter pack of ocean science and conservation accounts who post regularly and cover a variety of geographic and disciplinary perspectives. Follow these fine folks. 🦑🌎🧪🐠 go.bsky.app/HYBnbQn
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Tessa Hill @tessahill.bsky.social · 22/11/2024
You are so welcome- there are so many amazing women that now there are two starter packs!! go.bsky.app/4wMsfX4
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Kelly P Bushnell, PhD 🌊 @drkelpy.bsky.social · 22/11/2024
Thanks @tessahill.bsky.social for creating this one! 🌏🌊💪💙 go.bsky.app/7MdiLgo
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Dan MacGuigan @dmacguig.bsky.social · 24/11/2024
Mind adding me too?
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Alex Wild @alexwild.bsky.social · 23/11/2024
I hope federally funded scientists are preparing for large scale, bad faith attacks by Musk and his troll army. It’s pretty clear the DOGE operation is going to take snippets of grant proposals and papers, present them out of context, and direct weaponized harassment of individual people.
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Alex Wild @alexwild.bsky.social · 23/11/2024
Elon Musk takes far more federal dollars with far less oversight than any of the public scientists facing attacks. People who come under attack should respond by making sure anyone listening knows how much federal money Musk makes, and how he shields it from scrutiny.
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popgengoogling.bsky.social @popgengoogling.bsky.social · 24/11/2024
Could God make a demographic history so complex even she couldn't estimate N_e
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popgengoogling.bsky.social @popgengoogling.bsky.social · 23/11/2024
Is "clean-burning" coalescent a myth?
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popgengoogling.bsky.social @popgengoogling.bsky.social · 22/11/2024
Top 10 Hill-Robertsons to Die On
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Su-In Lee @suinlee.bsky.social · 23/11/2024
Here is a #compbio starter kit! go.bsky.app/QVPoZXp To all the #Bioinformatics #Genomics #MachineLearning folks: please RP and let’s build this together!
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Dan MacGuigan @dmacguig.bsky.social · 23/11/2024
Mind adding me too?
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Dan MacGuigan @dmacguig.bsky.social · 20/11/2024
In honor of #GIS Day, here's one of my favorite #river maps I made as part of my Hidden Rivers Twitter series. Perhaps it's time to restart that on Bluesky...
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Dan MacGuigan @dmacguig.bsky.social · 20/11/2024
Nice! Linking it here. go.bsky.app/ULRG7Wf
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Dan MacGuigan @dmacguig.bsky.social · 20/11/2024
Hi Chris, would you mind adding me too? Thanks for putting this together!
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Dan MacGuigan @dmacguig.bsky.social · 20/11/2024
Is there already a fish starter pack?
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Michael Landis @landismj.bsky.social · 19/11/2024
Here's a starter pack for early career researchers in evolutionary biology. I prioritized the most-junior folks, and this list quickly filled up with undergrads, grad students, and postdocs. Might do another list later, but I'm tired. Have fun everyone! 🐒 #evobio go.bsky.app/MzND7nX
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Dan MacGuigan @dmacguig.bsky.social · 17/11/2024
I wouldn't mind being added! @dmacguig.bsky.social
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Dan MacGuigan @dmacguig.bsky.social · 11/09/2024
Thanks Liz!
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Dan MacGuigan @dmacguig.bsky.social · 10/09/2024
Thank you! Just moved here last week
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Dan MacGuigan @dmacguig.bsky.social · 10/09/2024
First day on the job as a NOAA Fisheries Research Biologist, stationed at the National Systematics Lab in the Smithsonian National Museum of Natural History. I'll be developing and streamlining bioinformatics workflows, as well as leading and supporting research on systematics, evolution, and more!
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Dan MacGuigan @dmacguig.bsky.social · 05/03/2024
Also featured in Science. Thank you for the write-up @scattercushion.bsky.social!
science.org
These gars are the ultimate ‘living fossils’
Fish’s genomes are so static that groups whose last common ancestor lived during the time of the dinosaurs can produce fertile hybrids today
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Dan MacGuigan @dmacguig.bsky.social · 05/03/2024
Check out our new paper! Gars have an extremely low rate of molecular evolution compared to other vertebrates, much slower than most other "living fossil" lineages. With co-lead Chase Brownstein, plus Daemin Kim, Oliver Orr, Liandong Yang, @solomonrdavid.bsky.social, Brian Kreiser, and Tom Near.
doi.org
The genomic signatures of evolutionary stasis
Abstract. Evolutionary stasis characterizes lineages that seldom speciate and show little phenotypic change over long stretches of geological time. Although lin
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