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Dan MacGuigan @dmacguig.bsky.social · 08/09/2026

New paper in Systematic Biology! We show how micro-synteny can help resolve a tricky fish #phylogenetic problem where traditional sequence-based analyses fall short. Genomes archive evolutionary history in more than just their basepairs. doi.org/10.1093/sysb... #fish #genomics #evolution

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Dan MacGuigan @dmacguig.bsky.social · 08/07/2026

Check out our new paper linking #genomics and #geology with #evolution in a group of freshwater #fish. Grateful to have played a small part in this exciting study led by @dkimfish.bsky.social , Dr. Maya Stokes, and @tjnear.bsky.social. doi.org/10.1093/evol...

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Dan MacGuigan @dmacguig.bsky.social · 02/07/2026

Working with mitogenomes for eDNA, phylogenetics, etc, but not sure what's available on GenBank? Maybe your study group has weird mitogenome features? Come explore with with my new GenBankMitoReview tool! github.com/dmacguigan/G... #DNA #bioinformatics #eDNA #GenBank

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Dan MacGuigan @dmacguig.bsky.social · 27/12/2025

Huge congrats to my mentee @pfschwarz.bsky.social on her first first-author paper! Three-way secondary contact and mosaic hybridization in darters. Plus a bonus comparison of ddRAD vs lcWGS. @fishgenomes.bsky.social @tjnear.bsky.social #fish #evolution #genomics doi.org/10.1093/evol...

Map and phylogeny of complex hybrid zone between two darter species

Comparison of Fst estimates from ddRAD vs lcWGS

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Dan MacGuigan @dmacguig.bsky.social · 22/09/2025

Check out our new preprint! We compare sequence versus synteny approaches for resolving a challenging #phylogenetic problem. In this case, synteny is far more informative! Also includes the first chromosome-level #genome for the enigmatic #fish family Gyrinocheilidae. doi.org/10.1101/2025...

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Dan MacGuigan @dmacguig.bsky.social · 20/11/2024

In honor of #GIS Day, here's one of my favorite #river maps I made as part of my Hidden Rivers Twitter series. Perhaps it's time to restart that on Bluesky...

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Dan MacGuigan @dmacguig.bsky.social · 10/09/2024

First day on the job as a NOAA Fisheries Research Biologist, stationed at the National Systematics Lab in the Smithsonian National Museum of Natural History. I'll be developing and streamlining bioinformatics workflows, as well as leading and supporting research on systematics, evolution, and more!

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Dan MacGuigan @dmacguig.bsky.social · 25/10/2023

Time to try out yet another Twitter alternative. Hello fellow scientists of Bluesky! Bonus fish pic for your time - a fired up male Johnny Darter, Etheostoma nigrum.

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