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Simona Della Valle

@dellavallesimo.bsky.social
31 followers 30 following 1 posts

Synthetic biologist, farming microbes for sustainability • Research Associate @ UWA • Formerly PhD @ox.ac.uk @oxengsci.bsky.social • she/her

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Reposted by Simona Della Valle
Trends in Biotechnology @cp-trendsbiotech.bsky.social · 16/03/2025
Online now: Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
dlvr.it
Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
This study developed two simple, efficient, and rapid genome editing tools termed Self-splicing Intron-Based Riboswitch-Cas9 (SIBR-Cas9) and SIBR2.0-Cas12a, for editing the genome of the industrially relevant microbial strain Cupriavidus necator H16.…
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Reposted by Simona Della Valle
Beau Dronsella @beaubd.bsky.social · 14/03/2025
🚨Check out this amwesome new CRISPR tool for highly efficient genome engineering in C. necator led by @dellavallesimo.bsky.social and @eorsi.bsky.social 🔥🔥🔥
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Reposted by Simona Della Valle
labnikel.bsky.social @labnikel.bsky.social · 16/03/2025
Microbes like Cupriavidus necator naturally grow on #renewable feedstocks ♻️🧫 (CO₂, formate, hydrogen), yet their potential remains untapped due to the lack of efficient genetic tools... 1/2 www.cell.com/trends/biote...
cell.com
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Simona Della Valle @dellavallesimo.bsky.social · 17/03/2025
Our new #CRISPR toolkit for C. necator, built on SIBR-Cas technology, is now in press - an incredible collaboration with @eorsi.bsky.social, @copabio.bsky.social and many others🧪🧬⏳✂ Check out the thread below for details on genome editing + controlling gene expression by splitting a gene in two!
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