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DECISION Horizon2020

@decision4liver.bsky.social
252 followers 304 following 73 posts

DECISION is an international, EU-funded research project on decompensated cirrhosis to identify new combinatorial therapies based on systems approaches. 🌐 decision-for-liver.eu

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DECISION Horizon2020 @decision4liver.bsky.social · 05/08/2026
🆕publication in nature communications! Blood #multiomics revealed molecular networks linking lipid mediators, mitochondrial dysfunction and inflammation with progression to #ACLF and short-term mortality. 🔓 www.nature.com/articles/s41... #Hepatology #LiverSky
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DECISION Horizon2020 @decision4liver.bsky.social · 23/06/2026
🎉 DECISION video series complete! 💯 Explore short explainers on #cirrhosis, #ACLF, immune dysfunction, epigenetics, extracellular vesicles, single-cell technologies, and MASH research. 🎥 Full playlist: www.youtube.com/playlist?lis... #LiverDisease #SciComm
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DECISION Horizon2020 @decision4liver.bsky.social · 02/06/2026
What happens before cirrhosis patients suddenly deteriorate? 🪫 Single-cell analysis reveals that monocytes lose energy before organ failure, a signal linked to infections, disease progression, and survival. 🎥 Watch: youtu.be/D1aH-RC6DsM #LiverSky #cirrhosis #liverdisease
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DECISION Horizon2020 @decision4liver.bsky.social · 30/05/2026
Closing out at #EASLCongress! @rautoupe.bsky.social co-chairs a meet-the-expert session on #liquidbiopsy strategies for #liverdiseases Key questions • What works now and which variables matter? • Where's the near-term value? • What mistakes should we avoid? #EASL2026 @hopitalbeaujon.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 29/05/2026
Congrats to Juan Bañares (@vhir.bsky.social) for winning this year's EASL Daniel Alagille Award 🙌 🙌Two-year fellowship 🙌 25k funding Prof. Alagille (1925–2005), French paediatric hepatologist, named the Alagille Syndrome & contributed tremendously to the field. @easlnews.bsky.social #EASLCongress
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DECISION Horizon2020 @decision4liver.bsky.social · 28/05/2026
DECISION member Carlo Alessandria (Università degli Studi di Torino) was part of today's General Session I and contributed a talk on Transjugular intrahepatic portosystemic shunt for refractory hepatic hydrothorax in #cirrhosis: a multicenter European study #EASLCongress #EASL2026 #Hepatology
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DECISION Horizon2020 @decision4liver.bsky.social · 28/05/2026
We are thrilled to congratulate Prof. Paolo Angeli on winning the 2026 EASL Recognition Award. His scientific contributions, leadership, and clinical excellence set a remarkable standard for the field. Congratulations, Prof. Angeli! @unipd.bsky.social @easlnews.bsky.social #EASL2026
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Reposted by DECISION Horizon2020
concentris research management gmbh @concentris.bsky.social · 28/05/2026
📢 Full house at the EF CLIF Networking Session today at #EASLCongress here in their local Barcelona 😎 An exciting new initiative is a new #MasterProgramme, starting in Fall 2026🎓 #cirrhosis #ACLF #LiverFailure #EASL2026 @decision4liver.bsky.social @microb-predict.bsky.social @a-tango.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 27/05/2026
Final session of the day, but an important one nonetheless: Raj Mookerjee (@ucl.ac.uk) presents 'Connected patients (Wearables, implantable sensors, remote follow-up)', during the Postgrad Course: Diagnostics in liver diseases - Shaping the Future #EASL2026 #wearabletech #liverdisease #hepatology
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DECISION Horizon2020 @decision4liver.bsky.social · 27/05/2026
📱 Remote patient monitoring reduced 90-day liver-related hospitalizations in patients with acutely decompensated cirrhosis. #POSTER TOP-469-YI by Alberto Calleri et al. #EASL2026 #DigitalHealth #Cirrhosis
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DECISION Horizon2020 @decision4liver.bsky.social · 27/05/2026
In the co-session 'Patient/provider communication', @korenjak.bsky.social (president of @europeliver.bsky.social) stresses three vital in this communication relationship: ⏳ Time 📍Point-of-view 💬Miscommunication @microb-predict.bsky.social @a-tango.bsky.social #EASL2026 #EASLCongress
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DECISION Horizon2020 @decision4liver.bsky.social · 27/05/2026
🧪 Baseline serum albumin may help identify which patients with cirrhosis benefit most from long-term albumin therapy. #POSTER TOP-455-YI by Enrico Pompili et al. #EASL2026 #Cirrhosis #Hepatology
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DECISION Horizon2020 @decision4liver.bsky.social · 27/05/2026
Full house at the Postgraduate Course: Diagnostics in liver diseases - Advanced chronic liver disease! Joan Genesca (@vhir.bsky.social) co-presents 'From cirrhosis to #cACLD through modern diagnostics' with Prodromos Hytiroglou. cACLD = compensated Advanced Chronic Liver Disease #EASL2026
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DECISION Horizon2020 @decision4liver.bsky.social · 27/05/2026
Continuing our networking programme with Estefania Huergo from @navarrabiomed.bsky.social, who presents about epigenomics on patients with acute decompensated cirrhosis #EASL2026 #epigenomics @easlnews.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 27/05/2026
Next up: @frankuschner.bsky.social ner.bsky.social from @medblab.bsky.social is presenting new DECISION research on #ACLF #decompensation #EASL2026
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DECISION Horizon2020 @decision4liver.bsky.social · 27/05/2026
We're ready to welcome y'all at the DECISION networking session at the cirrhosis & complications track hub at #EASL2026! 🙌 First things first: To set the scene, project coordinator @rautoupe.bsky.social delivers a very brief intro to the DECISION project. #decompensatedcirrhosis #EASL2026
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DECISION Horizon2020 @decision4liver.bsky.social · 27/05/2026
Greetings from the DECISION Investigator Meeting at #EASL2026: Study updates and collaborative discussions with Paolo Caraceni & @rautoupe.bsky.social #ClinicalTrials #cirrhosis
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DECISION Horizon2020 @decision4liver.bsky.social · 21/05/2026
#EASL2026 is right around the corner!✨ Also, join our Networking Session and meet Pierre-Emmanuel Rautou, Estefanía Huergo, and Frank Uschner, who will present some exciting new DECISION research. 📍 Cirrhosis & Complications Track Hub 📆 Wednesday, 27 May 🕜 13:45 - 14:15h See you in Barcelona 🪭!
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DECISION Horizon2020 @decision4liver.bsky.social · 23/04/2026
Why do some cirrhosis patients suddenly deteriorate? #DNAmethylation changes are linked to worse outcomes in acute decompensation, pointing to a key role of #epigenetic regulation in disease progression. 🎥 Watch the explainer: youtu.be/yzTTzx68Sq8 @europeliver.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 12/03/2026
Therapeutic options for MASLD & MASH remain limited. A new standardized rapid animal model reproduces key features of metabolic liver disease within ~8 weeks, supporting faster #preclinical development. 🎥 Watch the video: youtu.be/n-YC_Dpko2A @frankuschner.bsky.social #LiverSky #Hepatology
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DECISION Horizon2020 @decision4liver.bsky.social · 03/03/2026
Acute decompensation of cirrhosis carries high 90-day mortality, but prediction remains challenging. Adding signatures of large #extracellularvesicles may improve scores and prediction. 🎥 youtu.be/24-STOSjLeY #EFCLIF @rautoupe.bsky.social @easlnews.bsky.social @europeliver.bsky.social #LiverSky
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DECISION Horizon2020 @decision4liver.bsky.social · 24/02/2026
In this video, we explore how emergency granulopoiesis, the rapid production of immune cells during crisis, becomes dysregulated in liver failure. 🎥 Watch here: youtu.be/ebN14TCLE24 #LiverSky #LiverFailure #LiverDisease #TranslationalResearch
youtu.be
Emergency Granulopoiesis in Liver Failure: When the Immune System Goes into Chaos
YouTube video by concentris research management
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DECISION Horizon2020 @decision4liver.bsky.social · 15/01/2026
📺New masterclass! ‘Data repositories & their access and publication rights’ covers the history of databases, an overview of repositories used in DECISION & provides a hands-on recipe on how to make the best out of different types of data ⏯️ youtu.be/aoA0WC1yaqs #bioinformatics
youtu.be
Data repositories and their access and publication rights | Masterclass in bioinformatics
YouTube video by concentris research management
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DECISION Horizon2020 @decision4liver.bsky.social · 16/12/2025
DECISION's Year-in-Review2️⃣0️⃣2️⃣5️⃣ 💙Networking session at EASL2025 🩵New publication on maladaptive emergency granulopoiesis 💙Met at Final General Assembly in Bologna 🩵Released 3 high-level lectures We look forward to continuing our collaboration in 2026, finishing strong, and maximizing our impact 💪
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DECISION Horizon2020 @decision4liver.bsky.social · 09/12/2025
New keynote out now! 🌟 Prof. Rubén Francés explains how LSECtin shapes immune tolerance and inflammation in advanced chronic liver disease. Watch here: www.youtube.com/watch?v=pY9H... #LiverSky #cirrhosis #inflammation
youtube.com
The Role of LSECtin in Regulating Inflammation in Advanced Chronic Liver Disease | DECISION Keynote
YouTube video by concentris research management
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DECISION Horizon2020 @decision4liver.bsky.social · 27/11/2025
New DECISION study in @jhepatology.bsky.social: maladaptive emergency granulopoiesis predicts poor outcomes in acutely #decompensatedcirrhosis. This could guide early identification and novel therapies. www.sciencedirect.com/science/arti... #ACLF #LiverSky #Hepatology @easlnews.bsky.social
sciencedirect.com
Maladaptive emergency granulopoiesis predicts poor outcomes in patients hospitalized with decompensated cirrhosis
Whether analysis of whole blood transcriptome assessed on admission of patients with acutely decompensated cirrhosis (ADC) without acute-on-chronic li…
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DECISION Horizon2020 @decision4liver.bsky.social · 10/10/2025
That’s a wrap on our final DECISION GA! From COMBAT & PROSPECT updates to forward-looking discussions and feedback, we’re proud of our shared achievements and motivated to keep advancing ACLF & decompensated cirrhosis research together. #LiverSky
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DECISION Horizon2020 @decision4liver.bsky.social · 09/10/2025
Our final GA is a look back and forward - from major scientific milestones to future discoveries! After a keynote by Prof. Rubén Francés, partners shared results on omics integration, biomarkers & systems medicine - and closed today with a masterclass on data repositories. #cirrhosis
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DECISION Horizon2020 @decision4liver.bsky.social · 01/10/2025
Next week: the final DECISION General Assembly in Madrid! 🎉 Celebrating 5+ years of science, collaboration, & results @rautoupe.bsky.social  @concentris.bsky.social  @navarrabiomed.bsky.social  @bioeticayderecho.bsky.social  @medblab.bsky.social  @europeliver.bsky.social  @easlnews.bsky.social et al
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DECISION Horizon2020 @decision4liver.bsky.social · 24/09/2025
The latest DECISION Masterclass is live! 💡 Clinical Bioinformatics – It’s More Than Pressing a Button with Núria Planell, Cristina Sanchez & David Gomez-Cabrero. Watch here: youtu.be/UBm1_JGhw6M #Bioinformatics #ClinicalResearch #ACLF
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DECISION Horizon2020 @decision4liver.bsky.social · 28/07/2025
Today is #WorldHepatitisDay! We spotlight two DECISION partners deeply committed to #liverhealth: 🔬 @easlnews.bsky.social – advancing #hepatology research 🧡 @europeliver.bsky.social – amplifying the voice of liver patients Together, we work toward a healthier future beyond ACLF. #Cirrhosis
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DECISION Horizon2020 @decision4liver.bsky.social · 30/06/2025
🔥 We’ve hit 50% recruitment in the #COMBATtrial! Huge thanks to all involved!💙 @rautoupe.bsky.social @hopitalbeaujon.bsky.social @hospitalclinic.bsky.social @rwth.bsky.social @uni-muenster.de @brunslab.bsky.social @medblab.bsky.social @frankuschner.bsky.social #LiverSky #ClinicalTrial
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DECISION Horizon2020 @decision4liver.bsky.social · 26/06/2025
🎥 New keynote online! Prof. Richard Moreau, Director of #EFCLIF, explores immune dysfunction in AD & #ACLF and suggests a common mechanism behind inflammation & immune deficiency. Watch now 👉 youtu.be/KWoUbTsNjQM  #LiverSky #Hepatology
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DECISION Horizon2020 @decision4liver.bsky.social · 17/06/2025
🎉 Exciting news: We’ve surpassed 500 followers on @linkedin.com! Follow us there for updates on trials, science, and more 👉 www.linkedin.com/company/deci... #ClinicalResearch #DECISIONproject
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DECISION Horizon2020 @decision4liver.bsky.social · 02/06/2025
Consider joining this event by @a-tango.bsky.social and @crowdhelix.com! "Industrial Perspective on Drug Development Challenges for Clinical Trials" 📅 4th June 2025 🕚 11:00 am CEST / 🕙 10:00 am BST Register via this link: inevent.uk/en/Crowdheli...
inevent.uk
Industrial Perspective on Drug Development Challenges for Clinical Trials - Website
More than ten million people worldwide suffer from decompensated cirrhosis, often as a result of severe alcoholic hepatitis (sAH) or other chronic liver diseases. In its final stages, decompensated ci...
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DECISION Horizon2020 @decision4liver.bsky.social · 20/05/2025
It’s #ClinicalTrialsDay! At DECISION, we’re proud of our COMBAT & PROSPECT trials advancing care in decompensated cirrhosis. 💡COMBAT Q&A videos in multiple languages help engage patients ➡️ www.youtube.com/playlist?lis... Thanks to all who make our trials possible! #LiverResearch
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Reposted by DECISION Horizon2020
concentris research management gmbh @concentris.bsky.social · 10/05/2025
✨ #PosterTour today at #EASLCongress 2025: All our 3 Horizon2020 #LiverResearch projects in 1 session! Topic: #Cirrhosis & #PortalHypertension Chair: Maria Papp 💡 Big moments: #AMMON-OHE model for post-#TIPS #encephalopathy (Rajiv Jalan) #Terlipressin response in AKI-HRS w/ CKD (Frank Uschner)
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DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
Clinical trajectories of patients with cirrhosis and ascites receiving long-term albumin #POSTER SAT-145-YI by Enrico Pompili (UNIBO) proposes a personalized management approach for patients with cirrhosis and ascites, based on real-world data from long-term albumin therapy. #EASL2025
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DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
🩺 Impact of diabetes mellitus on clinical outcomes in patients with acutely decompensated cirrhosis #E_POSTER SAT-184-YI by Mimma Bonomo (UNITO) explores how coexisting diabetes mellitus affects prognosis in patients hospitalized with acute decompensation of cirrhosis. #EASL2025
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DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
🦠The recovery failure of fecal microbiota diversity in patients after liver transplant is associated with a complicated postoperative course #POSTER SAT-518 by @beccsipollsi.bsky.social from @rwth.bsky.social at #EASL2025 @brunslab.bsky.social @easlnews.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
🧪 Acute kidney disease in acutely decompensated cirrhosis: impact on clinical outcomes #POSTER SAT-122-YI by Alberto Calleri (UNITO) examines how acute kidney disease affects outcomes in patients with acutely decompensated cirrhosis. 📅 Presented at #EASLCongress | #EASL2025 @easlnews.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
❤️ Cardiac performance is impaired in patients with proven alcohol-related hepatitis and predicts 3-month mortality in this patient population #POSTER SAT-503-YI by Pierre-Emmanuel Rautou (@inserm.fr, APHP, EF CLIF) 📅 Presented at the #EASLCongress | #EASL2025 @easlnews.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
Back in the Abstract Session: Theresa Wirtz presents her scRNA-seq work on monocyte subsets and ACLF risk. @rwth.bsky.social @brunslab.bsky.social @easlnews.bsky.social #Cirrhosis #ACLF #EASL2025"
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DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
Estefania Huergo presents methylation data in AD patients, selected as best Young Investigator abstract in Basic Science at #EASL2025 - Congrats! 🎉 @navarrabiomed.bsky.social @easlnews.bsky.social #Epigenetics #LiverResearch
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DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
Javier Fernandez (FCRB) is giving the hepatologist perspective on management of MDR infections in cirrhosis as part of the EASL/ESCMID Symposium: MDR infections - a challenge in decompensated cirrhosis at #EASL2025 #LiverDisease #Cirrhosis #Hepatology @easlnews.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
Is the etiological work-up of #PSVD a one-size-fits-all? DECISION consortium member Lucile Moga from APHP takes part in EASL/ VALDIG's session on "Do's and Don'ts in the management of Porto-Sinusoidal Vascular Disease". #EASLCongress #EASL2025 #LiverResearch @easlnews.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 09/05/2025
How do you build&lead a successful research team? The next generation of PIs learned straight from the best in today's workshop “How to Start a Research Group: From Postdoc to PI" as @rautoupe.bsky.social shared practical insights on building&maintaining a high-performing team. @inserm.fr #EASL2025
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DECISION Horizon2020 @decision4liver.bsky.social · 09/05/2025
DECISION consortium member Sophie Lotersztajn from the French research institute @inserm.fr at a late-afternoon abstract session today at #EASLCongress in Amsterdam, the Netherlands, about #fibrosis, #hepatocyte and #liver #regeneration. 🩺 #EASL2025 @easlnews.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 09/05/2025
🔬 #POSTER FRI-222 by Thierry Gustot (EF CLIF) proposes one-week criteria to assess the appropriateness of continuing intensive care in ACLF patients who are not candidates for liver transplantation. #EASL2025 @easlnews.bsky.social
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DECISION Horizon2020 @decision4liver.bsky.social · 09/05/2025
📊 Fibroblast growth factor 19 (FGF-19) predicts transplant free-survival in critically ill patients with acute-onchronic liver failure #POSTER FRI-199 by @beccsipollsi.bsky.social 📅 #EASLCongress | #EASL2025 @easlnews.bsky.social
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