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Tony Bruns (Bruns Lab Aachen)

@brunslab.bsky.social
576 followers 503 following 1 posts

Liver Disease Research. Our primary objective is to improve patient care focussing on the gut-liver axis in cirrhosis, peritoneal immunity & spontaneous bacterial peritonitis, acute-on-chronic liver failure, and cirrhosis-related immune dysfunction.

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Reposted by Tony Bruns (Bruns Lab Aachen)
Achille Broggi🧪👨🏼‍🔬🔬 @achillebro.bsky.social · 21/07/2025
At the beautiful European mucosal immunology group conference #emig in Aachen ready for two days of great #mucosalimmunology sciences #interferosky #gastrosky 🧪
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Reposted by Tony Bruns (Bruns Lab Aachen)
DECISION Horizon2020 @decision4liver.bsky.social · 30/06/2025
🔥 We’ve hit 50% recruitment in the #COMBATtrial! Huge thanks to all involved!💙 @rautoupe.bsky.social @hopitalbeaujon.bsky.social @hospitalclinic.bsky.social @rwth.bsky.social @uni-muenster.de @brunslab.bsky.social @medblab.bsky.social @frankuschner.bsky.social #LiverSky #ClinicalTrial
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Reposted by Tony Bruns (Bruns Lab Aachen)
United European Gastroenterology @myueg.bsky.social · 12/05/2025
Check out this electric insight from our Rising Star 2025, Carolin Schneider! ⭐ UEG Rising Star Awards are annually given to 10 of the most promising, emerging scientists. 🏆 🏆 Access Carolin's publication: bit.ly/3DDKzdX #myUEGcommunity
a woman wearing glasses and a red jacket
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Reposted by Tony Bruns (Bruns Lab Aachen)
The Baveno Cooperation: an EASL Consortium @bavenocoop.bsky.social · 09/05/2025
💉 Albumin duration & AKI response in cirrhosis Eva M. Schleicher (Mainz) – #EASL2025 🕒 24h albumin new rule questioned 🏆 EASL AKI response definition wins 📈 20% of 24h NR improved at 48h ⚖️ Early vs late responders: Same mortality 🚨 Cr ↑ >16% @24h → terlipressin! 👇
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Reposted by Tony Bruns (Bruns Lab Aachen)
DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
Back in the Abstract Session: Theresa Wirtz presents her scRNA-seq work on monocyte subsets and ACLF risk. @rwth.bsky.social @brunslab.bsky.social @easlnews.bsky.social #Cirrhosis #ACLF #EASL2025"
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Reposted by Tony Bruns (Bruns Lab Aachen)
DECISION Horizon2020 @decision4liver.bsky.social · 10/05/2025
🦠The recovery failure of fecal microbiota diversity in patients after liver transplant is associated with a complicated postoperative course #POSTER SAT-518 by @beccsipollsi.bsky.social from @rwth.bsky.social at #EASL2025 @brunslab.bsky.social @easlnews.bsky.social
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Reposted by Tony Bruns (Bruns Lab Aachen)
DECISION Horizon2020 @decision4liver.bsky.social · 09/05/2025
Congrats on presenting your poster in the Track Hub 4 this afternoon, @beccsipollsi.bsky.social ! 🙌
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Reposted by Tony Bruns (Bruns Lab Aachen)
DECISION Horizon2020 @decision4liver.bsky.social · 09/05/2025
Next at the DECISION Networking Session at #EASL2025, Theresa Wirtz (UKA) presents scRNA-seq data showing a monocyte subset linked to ACLF risk. Fascinating translational science in action! @brunslab.bsky.social ky.social @easlnews.bsky.social ky.social #scRNAseq #ACLF
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Reposted by Tony Bruns (Bruns Lab Aachen)
Salvatore Piano @salvatore-piano.bsky.social · 11/03/2025
📣 ICA GLOBAL AKI study published in @lancetgastrohep.bsky.social 🗺️3,821 patients with cirrhosis ✅38% had AKI ⚠️discrepancies in AKI management and outcomes ⚠️ AKI ➡️22.9% 28-day mortality 🎯Need for equitable & standardized care www.thelancet.com/journals/lan...
thelancet.com
Global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis: the International Club of Ascites GLOBAL AKI prospective, multicentre, cohort study
This study found important regional differences in AKI severity, phenotype, management, and outcomes in patients with decompensated cirrhosis. Health-care coverage remains an important driver of survi...
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Tony Bruns (Bruns Lab Aachen) @brunslab.bsky.social · 24/12/2023
Immunology research on bacterial infections in patients with cirrhosis: The human inflammatory caspases 4 and 5 are differentially regulated in patients with immune dysfunction due to sepsis and In acute-on-chronic liver failure. www.frontiersin.org/articles/10....
frontiersin.org
The non-canonical inflammasome activators Caspase-4 and Caspase-5 are differentially regulated durin...
The non-canonical inflammasome, which includes caspase-11 in mice and caspase-4 and caspase-5 in humans, is upregulated during inflammatory processes and activated in response to bacterial infections ...
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