The bacterial cell cycle is an ensemble of integrated pathways that coordinates cell growth and division. Although these pathways contain a suite of promising antimicrobial targets, their functional o...

Brogan and Rudner report the identification of a microbial autoproteolytic domain that is structurally homologous to the GAIN domain of eukaryotic adhesion GPCRs. Rather than participating in transmem...

A specific isoform of PBP1b functions independently of the activator protein, LpoB, to drive generation of a wedge-like peptidoglycan structure that strengthens the division site in Escherichia coli.

The cell wall peptidoglycan (PG) protects virtually all bacteria from osmotic lysis and specifies cell shape. Synthesis of this exoskeleton is carr...

Group B Streptococcus (Streptococcus agalactiae, GBS) is a leading cause of invasive infections in neonates and adults. The adult gastrointestinal (GI) tract represents an understudied site of asympto...

Nature Communications - Bacteriocins include antimicrobial peptides (AMPs) that often disrupt the cytoplasmic membrane. Here, the authors describe TMcin (transmembrane helix-containing...