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Branko Rihtman

@cyanoney.bsky.social
697 followers 454 following 556 posts

Eukaryote growing prokaryotes so I can infect them with phages. 2024 BBSRC Fellow at the University of Warwick. Unapologetically leftist.

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Reposted by Branko Rihtman
Freya Harrison @friendlymicrobe.bsky.social · 25/09/2026
What‘s the biggest, most exciting or nagging unanswered question in biology? What do you really, really wish we knew the answer to? I’m crowdsourcing responses to these Qs for my welcome talk to new Biology undergrads next week. I’d love to know your thoughts - thank you in advance!
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Branko Rihtman @cyanoney.bsky.social · 25/09/2026
Jess is a great scientist and a wonderful mentor, highly recommended!
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Reposted by Branko Rihtman
Ellie Jameson @elliejameson.bsky.social · 22/09/2026
MScRes bursary of £2000 available at Bangor University to study Bacteriophages as natural biocontrols for plant pathogens. Deadline is 19th October. Please contact me for more details #PhageSky #MicroSky
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Branko Rihtman @cyanoney.bsky.social · 17/09/2026
What a great story and an excellent experimental model system. I'm sure there will be many exciting discoveries arising from this work! Congrats!!
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Branko Rihtman @cyanoney.bsky.social · 27/08/2026
Congrats Ryan and the team! Good job!
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Reposted by Branko Rihtman
Mark van Raaij @markvanraaij.eurosky.social · 26/08/2026
Please look at our structure of the Salmonella bacteriophage epsilon15 tailspike. We show activity for the “usual” LPS hydrolysis site and an esterase site by NMR and structures with LPS. It reveals multiple O-antigen binding sites and a protruding esterase domain www.biorxiv.org/content/10.6...
biorxiv.org
The structure of the Salmonella phage epsilon15 tailspike reveals multiple O-antigen binding sites and a protruding esterase domain
Many bacteriophages use tailspikes to degrade host bacterial polysaccharides, facilitating access to the outer membrane. The homotrimeric tailspikes of the Salmonella phage epsilon15 feature a slender...
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Branko Rihtman @cyanoney.bsky.social · 24/08/2026
This was first done more than 20 years ago, among others by Prof. Shimshon Belkin at HUJI. Reviewed here: doi.org/10.1016/S136...
doi.org
Redirecting
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Branko Rihtman @cyanoney.bsky.social · 19/08/2026
I don't think this research measures the mental reassurance component of having the Bunsen burner on as you work with open plates.
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Branko Rihtman @cyanoney.bsky.social · 31/07/2026
We should limit paper submission to 3 journals. If 3 separate journals (with different reviewers) reject the same paper, it shouldn't be published, until the authors show that they've addressed all the criticisms.
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Branko Rihtman @cyanoney.bsky.social · 16/07/2026
I read the name of the movie and now all the neighbourhood cats are in front of my house
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Reposted by Branko Rihtman
Osterman Ilya @ostermanilya.bsky.social · 13/07/2026
🚨 We're hiring! My new lab at EMBL Hamburg is looking for a Research Technician. I'm looking for someone excited by phages, metabolism, enzymes, structural biology and bacterial immunity—if you know the right person, please share this post!🧵⬇️ Apply here: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
embl.wd103.myworkdayjobs.com
Research Technician (Osterman Group – Metabolism-driven immunity)
EMBL Hamburg / CSSB The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organization, with more than 110 independent research groups across Heidelberg, Hamburg, Grenobl...
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Branko Rihtman @cyanoney.bsky.social · 10/07/2026
This is such a fantastic episode. Made even more fantastic by the singing.
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Branko Rihtman @cyanoney.bsky.social · 10/07/2026
I will never understand why people don't want to test for Covid anymore... It is so easy and readily available. In 15 minutes you know whether you have it or not. The COVID-Flu testing combo costs £4. Why wouldn't you want to know whether you should stay away from people for a few days or not?
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Reposted by Branko Rihtman
Sorek Lab @soreklab.bsky.social · 09/07/2026
Our paper out in Science today: The Metis defense system senses molecular byproducts released when a phage degrades the bacterial genome, and then prevents replication of the phage in the infected cell Congratulations @ostermanilya.bsky.social and co-authors!
science.org
Bacteria sense virus-induced genome degradation via methylated mononucleotides
Phages often degrade the genome of their bacterial host to individual nucleotides. Here we describe Metis, a bacterial defense system that directly senses phage-mediated host genome degradation. Metis...
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Branko Rihtman @cyanoney.bsky.social · 30/06/2026
I have yet to find a phage genome extraction kit that produces a yield comparable to the good old phenol chloroform extraction. Latest comparison: extraction from 20ml of lysate each, 340ng/μl with phenol, 81ng/μl with a commercial kit, in the same elution volume.
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Branko Rihtman @cyanoney.bsky.social · 30/05/2026
Oooooooh excellent. An attendable Evergreen!!
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Branko Rihtman @cyanoney.bsky.social · 14/05/2026
This is crazy
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Branko Rihtman @cyanoney.bsky.social · 11/05/2026
New version of Inphared!!! With improved capabilities, such as defence and anti defence annotation in phage genomes, predicted lifestyle annotation, constantly expanding curated phage genome database and other improvements! Check out the preprint with all the numbers.
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Branko Rihtman @cyanoney.bsky.social · 30/04/2026
It is comforting to know that in this world of social uncertainties, rising fascism, perpetual war, and global economic instability, Gibson cloning still works.
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Branko Rihtman @cyanoney.bsky.social · 28/04/2026
Very glad to see this out. A huge effort by a lot of people. Well done everyone!! www.microbiologyresearch.org/content/jour...
microbiologyresearch.org
Rolling out Plaque-2-seq: a single plaque sequencing approach enabling rapid, low-cost sequencing of phages directly from plaques
Rapid, accurate and scalable sequencing of bacteriophage genomes is critical to advance phage therapy, build phage biobanks and understand phage genomic diversity. Current methods are based on sequenc...
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Branko Rihtman @cyanoney.bsky.social · 20/04/2026
It makes me so angry that we have to justify this technology to people with primary-school level reading skills at best. And those people somehow got to have their thumb on the kill switch of the research that enables this life-saving treatment.
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Branko Rihtman @cyanoney.bsky.social · 17/04/2026
A scientific misconduct on so many levels. Not the least by the journal which 1) doesn't ensure that the study that they published collected the data in a way that can be shared, and 2) refuses to publish the guidelines for reviewers to prevent this from happening again. Retract.
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Branko Rihtman @cyanoney.bsky.social · 16/04/2026
Wow wonderful work, many congratulations @emmajbanks.bsky.social !!! Looking forward to hearing more about this and your other work when you visit us at @warwicklifesci.bsky.social next month!!!
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Reposted by Branko Rihtman
Freya Harrison @friendlymicrobe.bsky.social · 15/04/2026
Find out about how different host-mimicking environments alter P. aeruginosa biofilm from @kadeayomikun.bsky.social at poster 169 at #Microbio26
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Reposted by Branko Rihtman
Freya Harrison @friendlymicrobe.bsky.social · 14/04/2026
Cracking talk from @nreddy.bsky.social about her PhD work - designing polymers based on AMPs to kill troublesome biofilm bacteria, or to help antibiotics kill these bacteria #Microbio26
A woman talking in front of a projected slide. The slide shows a synergy plot - for a narrow range of polymyxin concentrations, any concentration of our polymer synergises with the polymyxin when used to co-treat Pseudomonas aeruginosa.
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Freya Harrison @friendlymicrobe.bsky.social · 14/04/2026
Come to #Microbio26 poster 192 to hear how @charisthompson.bsky.social is sensitising mycobacteria to beta-lactams by making them flip their wall-building strategy #MicroSky
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Branko Rihtman @cyanoney.bsky.social · 09/04/2026
What a wonderful read. Definitely keeping this for future reference.
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Branko Rihtman @cyanoney.bsky.social · 09/04/2026
Wonderful opportunity with a great PI!! Highly recommended.
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Branko Rihtman @cyanoney.bsky.social · 02/04/2026
This does my head in. There is ZERO evidence that phoH in bacteriophages in general, and cyanophages in particular, has anything to do with P metabolism. The evidence for phoH role in bacterial P metabolism is not very strong either. There is no harm in being careful in your interpretations.
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Branko Rihtman @cyanoney.bsky.social · 30/03/2026
Judging by what I've heard from my colleagues, this movie should come with a trigger warning for this reason. "may upset scientists"
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Branko Rihtman @cyanoney.bsky.social · 24/03/2026
Why are the worst possible people making the most important decisions?
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Branko Rihtman @cyanoney.bsky.social · 24/03/2026
with proliferation of transposon knockout libraries for different bacterial species (like Keio collection), I'm afraid that the art of generating knockouts via transformation is slowly going to die away.
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Reposted by Branko Rihtman
Freya Harrison @friendlymicrobe.bsky.social · 19/03/2026
#MicroSky people, have you ever grown a Staph aureus biofilm that forms a crispy or hard exterior crust (not in urine)? My MBio student Izabela has, and we are not finding much literature on this.
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Branko Rihtman @cyanoney.bsky.social · 27/02/2026
This is a fantastic achievement for Reform and I wish them to get the second largest number of votes in every election they ever stand in
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Reposted by Branko Rihtman
Freya Harrison @friendlymicrobe.bsky.social · 18/02/2026
During her PhD, Jenny found something unexpected: biofilm-deficient P. aeruginosa mutants were just as tolerant to antibiotics as the WT when grown in our cystic fibrosis lung model. But why? #MicroSky 1/n
Four graphs, showing the response of PA14 and an isogenic pel mutant, and PAO1 and an isogenic pel psl double mutant, to meropenem and colistin. There is no difference between the response of mutants and WTs.
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Branko Rihtman @cyanoney.bsky.social · 13/02/2026
"Why do you care about US politics?" No reason. No reason at all.
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Reposted by Branko Rihtman
Microbiology Society @microbiologysociety.org · 11/02/2026
On International Day of Women and Girls in Science 🔬👩‍🔬 We’re launching the Women Microbiologists Network: a member-led networking and discussions event for women in microbiology by Dr. Enas Newire. Read the news story and join: 🔗 microb.io/4ax5M5I
Audience attentively listening to speaker at the Women Microbiologist Network from Annual Conference 2025.
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Branko Rihtman @cyanoney.bsky.social · 03/02/2026
This is such a fascinating topic and brilliant work by @tosinorababa.bsky.social
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Branko Rihtman @cyanoney.bsky.social · 02/02/2026
Two questions which should be ask at the beginning of each project: 1. What's the question? 2. Which controls will you use?
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Freya Harrison @friendlymicrobe.bsky.social · 29/01/2026
Why should microbiologists be interested in historical infection remedies, and how can we best investigate them for antimicrobial discovery? Thoroughly enjoyed co-writing this Microbiology Primer with @tosinorababa.bsky.social www.microbiologyresearch.org/content/jour... #MicroSky #Ancientbiotics
microbiologyresearch.org
Microbial Primer: Ancientbiotics – making modern antimicrobials from historical infection remedies
The modern antibiotic era began in the early twentieth century, but humans have long used materials from the natural world to attempt to treat the symptoms of infection. In this primer, we will discus...
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Reposted by Branko Rihtman
Steven Robbins @stevenjrobbins.bsky.social · 28/01/2026
Curious, what's the best-practice tool at this point for taxonomically classifying long reads from metagenomes from less well-characterised environments? My impression is that Kraken will give lots of false positives and mis-classify taxa not in its database. Please share around for visibility.
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Branko Rihtman @cyanoney.bsky.social · 24/01/2026
This.
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Reposted by Branko Rihtman
Ian Lidbury @iandealidbury.bsky.social · 14/01/2026
In case you missed it. For any microbial ecologists, we recently published our long-standing study on identifying the major genes/molecular markers for glycine betaine degradation in environmental bacteria www.pnas.org/doi/full/10....
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Reposted by Branko Rihtman
Alexia Hapeshi @alexiahapeshi.bsky.social · 17/12/2025
Dear all, I am aware I have not been on the platform for a while but NanoSyrinx is hiring again so I thought I would share. If you are anyone you know is interested, take a look below: www.linkedin.com/jobs/view/43...
linkedin.com
NanoSyrinx hiring Bioinformatician - Structural Biology/Protein Design and Engineering in Coventry, England, United Kingdom | LinkedIn
Posted 10:01:39 AM. ABOUT THE COMPANY NanoSyrinx is an award-winning synthetic biology company focused on a novel…See this and similar jobs on LinkedIn.
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Branko Rihtman @cyanoney.bsky.social · 16/12/2025
Been using Prokka for years now, excellent annotating software. Looking forward to try Bakta
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Branko Rihtman @cyanoney.bsky.social · 12/12/2025
Interesting phys.org/news/2025-12...
phys.org
Fast-tracking a natural climate solution by compressing millennia of carbon capture into hours
What if it were possible to take a very slow geological process, one that takes thousands of years in nature, and speed it up so that it happens within hours, in order to slow the rate of global warmi...
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Branko Rihtman @cyanoney.bsky.social · 11/12/2025
Have I agreed to review a grant over Xmas? Of course I have 🤦
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Reposted by Branko Rihtman
Eleanor M. Townsend @emtownsend.bsky.social · 11/12/2025
Our pre-print on staff & students perspectives on EDI in Medicine is available now on Research Square www.researchsquare.com/article/rs-7... We looked at what students feel confident in learning, what the curriculum currently represents, and how to support staff to enhance EDI topics further.
researchsquare.com
Enhancing equality, diversity, and inclusion in the undergraduate medicine curriculum: staff and student perspectives
IntroductionIncorporating equality, diversity, and inclusion (EDI) themes into medical curricula is essential for preparing students to support a diverse patient population. This study evaluated the r...
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Reposted by Branko Rihtman
Séamus Holden 🔬🦠🧫 @seamusholden.bsky.social · 11/12/2025
@simonecoppola.bsky.social has made micromorph, the first native Python application and library for measuring bacterial morphology. It runs interactively in napari or can be easily integrated into automated Python scripts. It integrates deep learning cell segmentation and is easily extended 🔬🦠🧫
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Evelien Adriaenssens @evelienadri.bsky.social · 11/12/2025
I'm proud to share the latest methods work from my group. Led by @revathykri.bsky.social we wrote a book chapter on how we process and analyse viromes. Thanks to co-authors @rikhaagmans.bsky.social @ryancook94.bsky.social & Alise Ponsero link.springer.com/protocol/10....
link.springer.com
Virome Analysis
Viruses are omnipresent and the most abundant biological entities on the planet. They play a critical role in shaping the ecology and evolution of all life forms. This chapter provides methods to perf...
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