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CryoCloud @cryocloudio.bsky.social · 21/08/2026

v2.40 is live 🚀 Bringing you: Class flow plots · AutoClass2D results page · dynamic masking in Refine3D · 1.5× faster classifications and refinements. Video + release notes 👇 academics can sign up for free here: app.cryocloud.io #cryoEM #structuralbiology #SPA

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CryoCloud @cryocloudio.bsky.social · 19/08/2026

3D ligand visualisation is now built directly into the CryoCloud project table, allowing you to quickly inspect ligands across 100s of datasets in seconds. Interested in our CrystalCloud add-on? Email hi@CryoCloud.io #cryoEM #structuralbiology #drugdiscovery #biotech #CryoCloud #MX #crystallography

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CryoCloud @cryocloudio.bsky.social · 06/07/2026

CryoCloud v2.34 is out! Highlights include Live Analysis for real-time cryo-EM image processing, an Interactive Masking tool, Ligand Visual Inspector, and MolProbity validation. Find the full release notes here: connect.cryocloud.io/release-note... #cryoEM #structuralbiology

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CryoCloud @cryocloudio.bsky.social · 25/03/2026

CryoCloud Map of the Month: TRPV3 in lipid nanodisc We reprocessed EMPIAR-10400 using CryoCloud and achieved: 🚀 3.1 Å resolution (vs. 3.3 Å published) ⚡ 7 compute hours total Curious what your data would look like reprocessed with CryoCloud? 📧 hi@cryocloud.io

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CryoCloud @cryocloudio.bsky.social · 18/03/2026

🌟 Employee Spotlight: Gydo van Zundert Gydo brings a rare blend of scientific depth and product vision to CryoCloud. He leads our R&D team of scientific software developers, driving the development of novel algorithms and next-generation methods for #cryoEM data analysis. #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 16/03/2026

CryoCloud will be at the @instruct-eric.bsky.social Best Practices in Cryo-EM Workshop in Milan this week. On March 18, we’ll present a flash talk on how #CryoCloud can help #cryoEM facilities manage users, data storage, and scalable compute. Come say hi! 🔗 instruct-eric.org/events/best-...

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CryoCloud @cryocloudio.bsky.social · 13/03/2026

🚀 CryoCloud v2.23 is live 🔎 More visualisation in results pages: FSC curves and angular distribution plots (see GIF 👇) ⚡ Faster map viewing: cropped & downsampled map variants now load much faster in the UI 📘 connect.cryocloud.io/release-note... #CryoCloud #CryoEM

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CryoCloud @cryocloudio.bsky.social · 12/03/2026

🚨 CryoCloud Newsletter Alert Over the past few months, we’ve released multiple platform updates, published new technical content, launched our new website, and connected with the structural biology community at SBDD San Diego. 🔗 Full issue: connect.cryocloud.io/newsletter-m... #CryoEM #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 10/03/2026

We’ve had many new followers recently, so for those who may be new to CryoCloud — here’s a quick overview of how you can try the platform: tinyurl.com/yrb6vwc4 There are two ways to get started: 🔹Free academic account, or 🔹30-day evaluation trial Links are in the comments 👇 #CryoEM #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 05/03/2026

🚀 CryoCloud Webinar Series Cryo-EM datasets are getting larger, but processing them shouldn’t be harder. Join our April webinars on cryo-EM data processing and automated workflows with CryoCloud. 📅 Apr 16 - Academia 📅 Apr 23 - Industry Live demo + Q&A #CryoEM #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 03/03/2026

What does single particle analysis on CryoCloud look like? From dataset creation to particle picking and 2D/3D classification, here’s a short walkthrough: cryocloud.io/solution/end... Request a free academic account or a 30-day trial here: app.cryocloud.io/sign-up #CryoEM #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 26/02/2026

February Map of the Month: Aca2–RNA We reprocessed EMPIAR-11918 and achieved 2.76 Å in 50.5 compute hours. Sub-3 Å at ~40 kDa is a strong example of what modern cryo-EM workflows (and RELION with Blush) can deliver for small targets. 📧 hi@cryocloud.io #CryoEM #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 24/02/2026

🌟 Employee Spotlight: Thijmen van Buuren Over the past two years, Thijmen has strengthened CryoCloud’s automation workflows, advancing our research infrastructure and scalable data pipelines. As he wraps up his time with us, we thank him for his dedication and impact. All the best, Thijmen! 🚀

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CryoCloud @cryocloudio.bsky.social · 20/02/2026

🚀 CryoCloud v2.22 is live! What's new: 🧬 cryoDRGN-AI Ab Initio now available (see the GIF👇) ⚡ GPU-accelerated MotionRefine CC (alpha): 2–3× faster polishing 📊 Redesigned project overview 📺 Embedded viewers in multiple jobs 🔗 connect.cryocloud.io/release-note... #CryoEM #cryoDRGN

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CryoCloud @cryocloudio.bsky.social · 17/02/2026

🚀 We’ve launched a new CryoCloud website! CryoCloud has grown significantly over the past few years – more users, more deployments & ongoing technical development across infrastructure and automation. It was time for a website that reflects that evolution. 🌐 Take a look: www.cryocloud.io #cryoEM

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CryoCloud @cryocloudio.bsky.social · 13/02/2026

🚨 New blog: Automated cryo-EM analysis of the gastric proton pump We reprocessed EMPIAR-11057 using a fully automated end-to-end workflow: ⚡ 2.6 Å in 43.5 hr (vs 2.8 Å published) ⚡ 2.4 Å after CTF refinement ⚡ Improved ligand density 🔗 Full article: docs.cryocloud.io/blog/ #cryoEM #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 27/01/2026

🚀 CryoCloud v2.21 is live! This release delivers a major update to the workflows experience in CryoCloud: 🔹 Convert an existing project into a reusable workflow 🔹 Apply workflows mid-project to extend or repeat processing steps 📘 connect.cryocloud.io/release-note... #CryoCloud #CryoEM

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CryoCloud @cryocloudio.bsky.social · 22/01/2026

January Map of the Month: Gastric Proton Pump – Revaprazan Complex 🤖 2.6 Å map in 43h, fully automated, no user input 💡 All automation features are available to all CryoCloud users Curious how your data would look reprocessed with #CryoCloud? 📧 hi@cryocloud.io #cryoEM #DrugDiscovery

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CryoCloud @cryocloudio.bsky.social · 19/01/2026

🚀 CryoCloud v2.20 is live! This release introduces advanced job-branch cloning (see ⬇️), contamination-based filtering, and several performance improvements across the platform. 📘 Full release notes → connect.cryocloud.io/release-note... #CryoCloud #CryoEM

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CryoCloud @cryocloudio.bsky.social · 15/01/2026

🌟 Welcome to the team, Paddy O'Brien! 🇮🇪 We’re thrilled to welcome Paddy as our new Structural Biology Applications AI Intern. Fun fact: Paddy adds another nationality to CryoCloud’s already diverse mix, bringing us to 8 nationalities and counting! 🍀 Welcome aboard, Paddy! 🙌 #CryoCloud #CryoEM

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CryoCloud @cryocloudio.bsky.social · 14/01/2026

🔎 Before diving into new 2026 data, we’re looking back at the highlights from the last six months. ⚡️From receptors to kinases and fibrils, each dataset was reprocessed in CryoCloud, often within <2 days, and all resolved to high-quality maps between 2.3 and 3.2 Å. #CryoEM

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CryoCloud @cryocloudio.bsky.social · 08/01/2026

New year, new projects — and often new tools to evaluate. If you’re curious about CryoCloud, there are two simple ways to get started: 🔷 Free academic account 🔷 30-day evaluation trial Links in the comments 👇 #cryoEM #structuralbiology

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CryoCloud @cryocloudio.bsky.social · 24/12/2025

As 2025 comes to an end, thank you to the CryoCloud community. Every conversation, dataset, and piece of feedback helps us build a better platform for structural biology. From all of us at CryoCloud, wishing you a warm, restful holiday season and a great start to 2026. ✨

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CryoCloud @cryocloudio.bsky.social · 23/12/2025

CryoCloud Map of the Month (Holiday Edition 🎄): Alpha‑Synuclein Fibril For December’s edition, we reprocessed EMPIAR‑12229 and generated a 2.3 Å map of the in vitro alpha-synuclein fibril using CryoCloud. 🔬 Dataset size: 5,193 movies 🧠 Compute time: 56.5 hours #CryoEM

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CryoCloud @cryocloudio.bsky.social · 18/12/2025

📢 CryoCloud Newsletter: End-of-Year Edition is out! A huge thank you to our users, collaborators, and the structural biology community for being part of the journey this year 💙 👉 Read it here: connect.cryocloud.io/newsletter-d... #CryoCloud #CryoEM #StructuralBiology #DrugDiscovery

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CryoCloud @cryocloudio.bsky.social · 16/12/2025

🌟 Employee Spotlight: Boy Persoon As Co-Founder and CPO of #CryoCloud, Boy has been the driving force behind turning our ambitious product vision into a functional, user-first platform. If you’ve ever used our platform and thought “this just works” – Boy probably had something to do with it 🍀

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CryoCloud @cryocloudio.bsky.social · 12/12/2025

🚀 CryoCloud v2.18 is live! This release includes two new beta features designed to further automate #cryoEM workflows, along with other improvements. What’s new: 🔹 AutoClass2D – automatically select 2D classes using a reference .mrc file 🔹 Workflow Export & Import lnkd.in/eb8ic_TK #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 09/12/2025

🚨 New blog: GPU-accelerated motion correction Motion correction remains one of the slowest and most costly steps in #cryoEM workflows. So we rebuilt it from scratch. Our new in-house GPU-accelerated CryoCloud Motion Correction is designed for speed, scale and high throughput. lnkd.in/eiJgsYgJ

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CryoCloud @cryocloudio.bsky.social · 05/12/2025

🔥 Three years ago, the CryoCloud platform went live 🎉 Today, scientists from 25+ countries rely on it every day for analysing their structural biology data – and we couldn’t be prouder of how far things have come. Thank you to all our users, collaborators, and early supporters 💙 #CryoEM

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CryoCloud @cryocloudio.bsky.social · 05/12/2025

🚀 CryoCloud v2.17 is live! This release introduces Targets – a new way to organise datasets & projects around your molecule of interest. Targets make it easier to browse results, store reference files in one place and launch automated workflows. connect.cryocloud.io/release-note... #CryoEM

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CryoCloud @cryocloudio.bsky.social · 26/11/2025

November Map of the Month: CDK-activating kinase (CAK), an oncology target bound to the covalent inhibitor THZ1 💊 We reprocessed EMPIAR‑11793 and produced a 2.5 Å map of the ~85 kDa CAK-THZ1 complex using CryoCloud. 🔬 Dataset size: 12,572 movies 🧠 Total compute time: 52 hours #CryoEM #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 21/11/2025

🚀 CryoCloud v2.16 is live! This release introduces filament support, including filament picking, visualisation, and a new Initial Model job type for helical workflows. Full release notes → connect.cryocloud.io/release-note... #CryoEM #StructuralBiology

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CryoCloud @cryocloudio.bsky.social · 19/11/2025

🌟 Employee Spotlight: Anna Boronina Anna brings a strong mix of ML and software engineering to #CryoCloud. She’s behind our ML-based particle picker, which has expanded since its initial release to include contamination segmentation, models for diverse targets & lightning-fast performance. #cryoEM

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CryoCloud @cryocloudio.bsky.social · 13/11/2025

Back from a #PSDI2025 in Basel. Lots of good discussions and clear interest in practical ways to handle growing cryo-EM and X-ray data volumes. We shared results from our large-scale automated analysis of 53 EMPIAR datasets (key takeaways in the comment below!) #CryoEM #StructuralBiology

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CryoCloud @cryocloudio.bsky.social · 05/11/2025

We’re heading to #PSDI2025! Meet the CryoCloud team and don’t miss our talks: ⚡ Sun 9 Nov: Towards Automating Cryo-EM Data Analysis 🚀 Tue 11 Nov: Accelerating Data Analysis with CryoCloud Drop by our booth or book a chat 👇 connect.cryocloud.io/meetings/cry... #CryoEM #XrayCrystallography

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CryoCloud @cryocloudio.bsky.social · 28/10/2025

October Map of the Month: GLP-1R With pharma racing to develop next-generation obesity and diabetes drugs, this #GPCR needs no introduction 💊 We reprocessed EMPIAR-10673, showing GLP-1R bound to its natural ligand GLP-1, and achieved a 2.7 Å map on CryoCloud using 40 h of compute. #CryoEM

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CryoCloud @cryocloudio.bsky.social · 24/10/2025

🌟 Employee Spotlight: Tadej Satler (@tadejsatler.bsky.social) Tadej brings deep scientific and computational expertise to CryoCloud. His recent work on GPU-accelerated motion correction (MotionCorr CC) is a key step toward faster, more accessible cryo-EM. Proud to have him on the team! 🚀 #CryoEM

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CryoCloud @cryocloudio.bsky.social · 23/10/2025

🚀 CryoCloud version 2.13 is here! Highlights: 🔹 Adjust map visualisation with new, easily-accessible iso-level slider ⬇️ 🔹 Create particle subsets using metadata values 🔹 Clearer dataset-import feedback 🔹 Custom browser tab names, and more Full notes: connect.cryocloud.io/release-note... #CryoEM

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CryoCloud @cryocloudio.bsky.social · 17/10/2025

🚀 CryoCloud v2.12 is here! This release brings major project grid usability updates, including filtering by processing branch, so you can highlight an entire job tree and focus on one processing path at a time (preview below!) Full release notes: connect.cryocloud.io/release-note... #CryoEM

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CryoCloud @cryocloudio.bsky.social · 15/10/2025

⏰ Tomorrow! Join us for the CryoCloud #XRayCrystallography webinar featuring a short introduction to the new pipeline and a panel discussion on today’s challenges and opportunities in high-throughput XRC data processing. events.teams.microsoft.com/event/6f09a4... #CryoCloud #StructuralBiology

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CryoCloud @cryocloudio.bsky.social · 14/10/2025

🚀 CryoCloud MotionCorr – our new GPU-accelerated motion correction is here! Released last week as part of CryoCloud v2.11, our new GPU-accelerated motion correction algorithm delivers up to 4× faster performance than the legacy CPU-based Relion implementation. v2.11 notes: t.co/zK4YKotSWI #CryoEM

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CryoCloud @cryocloudio.bsky.social · 10/10/2025

🚀 CryoCloud v2.11 is here! Version 2.11 brings up to 4x faster motion correction, contamination detection in CryoCloud Picker (see a preview below!), and major performance boosts across the platform. Full release notes: connect.cryocloud.io/release-note... #CryoEM #CryoCloud

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CryoCloud @cryocloudio.bsky.social · 10/10/2025

⏳ 1 Week to Go! After introducing CryoCloud’s integration of Global Phasing’s Pipedream workflow, we’ll be joined by four experts to discuss the challenges and opportunities in high-throughput #XrayCrystallography. Register here: events.teams.microsoft.com/event/6f09a4...

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CryoCloud @cryocloudio.bsky.social · 07/10/2025

CryoCloud is heading to Women in Electron Microscopy #WeM2025 this week! We’re proud to sponsor this inaugural event supporting women in electron microscopy. Our own @ievadr.bsky.social will speak on cloud-native automation to enable high-throughput #cryoEM for drug discovery. See you there!

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CryoCloud @cryocloudio.bsky.social · 06/10/2025

📢 CryoCloud Newsletter – Issue #2 is here! 💎 New X-ray Crystallography pipeline 🧬 Biologics case studies: antibodies & vaccines 🚀 Platform release notes 🎤 CryoCloud at WeM 2025 👋 Team update: Welcome, Josh! 📅 Upcoming events & more Read it here: connect.cryocloud.io/newsletter-o... #cryoEM #XRC

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CryoCloud @cryocloudio.bsky.social · 03/10/2025

🚀 CryoCloud Platform Release 2.10.1 is here! This is a big one – CryoCloud now supports X-ray Crystallography alongside #cryoEM 💎 📖 Read the full release notes, including other improvements and bug fixes: connect.cryocloud.io/release-note... #CryoCloud #XrayCrystallography #StructuralBiology

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CryoCloud @cryocloudio.bsky.social · 02/10/2025

🚀 New in CryoCloud: Automated X-ray Crystallography Data Processing! Join our launch webinar on Oct 16 (11 AM ET | 5 PM CET) featuring a CDK2 case study + industry panel on high-throughput XRC. 👉 Register: lnkd.in/ev4e7K_h #StructuralBiology #XRayCrystallography #XRC #CryoEM

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CryoCloud @cryocloudio.bsky.social · 26/09/2025

📣 Live from the Dutch Structural Biology Meeting in Delft! Robert (@riborob.bsky.social) is presenting our CryoCloud poster on accelerating #cryoEM workflows. We’re also sponsoring the Poster Prize 🧦🎉 Big thanks to Arjen Jakobi (@cryotud.bsky.social) for organising. Excited for today’s discussions!

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CryoCloud @cryocloudio.bsky.social · 24/09/2025

September Map of the Month: Small Data, Big Insights ⚡️ From just 233 movies, CryoCloud delivered a 3.2 Å SARS-CoV-2 spike map in 3.5 h. Fast and efficient #cryoEM, exactly what vaccine design teams need when screening dozens of antigen variants per day. 📬 DM or hi@cryocloud.io for more info!

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CryoCloud @cryocloudio.bsky.social · 19/09/2025

Thrilled to welcome Dr Joshua White as Senior Application Scientist at CryoCloud! With deep expertise in single-particle analysis & end-to-end #cryoEM workflows, Josh will lead data analysis, user training & support. Excited to have his experience & energy on board! 🚀 @jbrwhite.bsky.social

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