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Jake Smith

@cryingem.bsky.social
621 followers 425 following 20 posts

EMBL 🇫🇷 Previously Oxford/RFI 🇬🇧

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Jake Smith @cryingem.bsky.social · 07/09/2026
huge congrats to Florian! 🍾🙌 very excited to image some cool looking bugs over the next few years 🔬🪼🦠
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Helena Watson @helenawatson.bsky.social · 25/04/2026
Preprint 🧵! I’m really excited to introduce BIGSMALL, an interleaved multi-magnification cryo-ET scheme bridging molecular and cellular scales in a single acquisition! BIGSMALL = 𝐁road 𝐈nformation 𝐆athering 𝐒trategy by 𝐌ultiscale 𝐀cquisition of lame𝐋𝐋a www.biorxiv.org/content/10.6... (1/6)
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Alice Auersperg @auersperga.bsky.social · 19/01/2026
Our new paper (with @biotay.bsky.social) is out and on the cover story of @currentbiology.bsky.social !!!! Veronika, a Carinthian mountain cow flexibly uses a “multi-purpose tool” to scratch herself. A video and more information will follow in the comments. www.cell.com/current-biol...
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Ariane Briegel @arianebriegel.bsky.social · 01/12/2025
CryoET of microbes inside an animal organ? Yes it’s possible! Check out our new preprint showing how we did it! What an amazing collaboration with amazing scientists who made this possible!
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Jake Smith @cryingem.bsky.social · 30/09/2025
if you have to do MFA twice in the same "day": go to bed
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Quanta Magazine @quantamagazine.org · 10/09/2025
Lokiarchaea are tricky to work with in the lab: they grow very slowly, exclusively in an oxygen free environment with the presence of symbiotic bacteria. But with careful nurturing, scientists hope to witness their cell division at work.
quantamagazine.org
Tiny Tubes Reveal Clues to the Evolution of Complex Life | Quanta Magazine
Scientists have identified tubulin structures in primitive Asgard archea that may have been the precursor of our own cellular skeletons.
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Jake Smith @cryingem.bsky.social · 31/08/2025
repurposing library monitors #upthearsenal
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Jake Smith @cryingem.bsky.social · 21/07/2025
hot (well, cold) off the press! ❄️ well done @glynnca.bsky.social & @michaelgrange.bsky.social & fabulous co-authors 👏🏼 #teamtomo #cryoET
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Jake Smith @cryingem.bsky.social · 19/06/2025
Delighted to see our work in press! 🙌🔬🧠 Thanks to @glynnca.bsky.social, @michaelgrange.bsky.social and the rest of the fabulous co-authors for all your contributions. Excited to see where in tissue structural cell biology goes next 👀! #liftlaughlove #teamtomo #whopper
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Jake Smith @cryingem.bsky.social · 25/04/2025
inspiring and relatable talk from @alisterburt.bsky.social #ccpem
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Jake Smith @cryingem.bsky.social · 22/04/2025
note to self: don't turn out of office replies on
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bioRxivpreprint @biorxivpreprint.bsky.social · 06/04/2025
Exploring shaped focused ion beams for lamella preparation www.biorxiv.org/content/10.1101/202…
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Michael Grange @michaelgrange.bsky.social · 07/03/2025
Check out our paper on Xenon milling of HPF samples, now online @naturecomms.bsky.social rdcu.be/eczIb
rdcu.be
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Jake Smith @cryingem.bsky.social · 05/03/2025
Barista: How caffeinated would you like to be? Me: Yes
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Hiro Imachi @hiro-imachi.bsky.social · 27/02/2025
Isolated in just 3 years! (previously, 12 years). We obtained two strains from 'Hodarchaeales', proposed to be closest to our archaeal ancestor. Our analysis suggests the ancestor was an anaerobic, syntrophic, peptidotrophic, archaeon with a simple intracellular structure and possible aerotolerance.
biorxiv.org
Eukaryotes' closest relatives are internally simple syntrophic archaea
Eukaryotes are theorized to have originated from an archaeal phylum Promethearchaeota (formerly 'Asgard' archaea)1,2. The first cultured representatives revealed valuable insight3,4 but are distantly ...
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Jake Smith @cryingem.bsky.social · 22/02/2025
A great opportunity! (especially to hear @glynnca.bsky.social spread the plasma gospel🙌🏻)
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Jake Smith @cryingem.bsky.social · 22/01/2025
Congrats Charlie & co.! The use of optogenetics for in tissue CLEM here is really elegant.
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Jim Woodgett @jwoodgett.bsky.social · 08/12/2024
A long read from 2017 but well worth the time for any scientist who both loves their job and and often finds themselves questioning their life decisions. www.danielnettle.org.uk/wp-content/u...
danielnettle.org.uk
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Jamie Blaza @jnb-lab.bsky.social · 29/11/2024
We have quite a range of PhD projects this year, covering cryo-EM methods, bacteriology/bioenergetics, and infection/antibiotics/vaccines. Would really appreciate if people can RT and share with their teams!
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Richard Held @rgsheld.bsky.social · 26/11/2024
Is there such thing as TEMTuesday? Maybe CryoETuesday? Myelinated axon cross section with microtubules and intermediate filaments:
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Jake Smith @cryingem.bsky.social · 15/11/2024
it is nicer over here
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