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Reposted by Connor Tsuchida

Innovative Genomics Institute @innovativegenomics.bsky.social · 04/11/2025

Congratulations to IGI alums @jro-hamilton.bsky.social @connortsuchida.bsky.social & team on the launch of Azalea Therapeutics!

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Reposted by Connor Tsuchida

Ryan Cross @scienceboss.bsky.social · 04/11/2025

Jennifer Doudna's latest startup, Azalea Therapeutics, launched with $82M. It's based on virus like particles developed by CEO Jenny Hamilton and a new CAR-T trick developed by UCSF's Justin Eyquem. Their goal? The ultimate CRISPR-based in vivo CAR-T. @endpts.com - endpoints.news/jennifer-dou...

endpoints.news

Jennifer Doudna startup launches with $82M to apply new CRISPR delivery technology to in vivo CAR-T

Nobel laureate Jennifer Doudna's Azalea Therapeutics raises $82M to develop new CRISPR delivery system for in vivo CAR-T cell therapies targeting blood cancers.

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Connor Tsuchida @connortsuchida.bsky.social · 23/12/2024

Great to see others corroborate the finding that CRISPR-Cas9 mediated DSBs can lead to chromosomal aberrations (tinyurl.com/yp2b9s7m). I always thought these findings weren’t meant to cause panic, but rather spur innovative solutions. Interesting to see pifithrin-a treatment do just that!

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Reposted by Connor Tsuchida

Amanda Alker @atp-alker.bsky.social · 30/11/2024

🚨 The Alker Lab is starting at the University of Rhode Island in early 2025 and we will be hiring! 🚨 If you are interested in marine microbiology, bacterial genetics and/or symbiosis, please consider reaching out! Repost to help spread the word 🪸🧪🧬🌊

The Alker lab at the University of Rhode Island is hiring (students, postdocs and lab staff)! We use cutting edge tools in microbiology to investigate marine animal symbioses. Email or DM for further inquiries

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Reposted by Connor Tsuchida

Joao Ascensao @joaoascensao.bsky.social · 22/11/2024

We usually think of genetic drift as the predominant stochastic force in evolving populations. But working with some model microbial populations, we found a distinct source of demographic stochasticity that scales (and behaves) differently than drift Learn more in our new paper 👉 rdcu.be/d07Np

rdcu.be

Asynchronous abundance fluctuations can drive giant genotype frequency fluctuations

Nature Ecology & Evolution - Based on a combination of experiments and modelling, this study shows large stochastic fluctuations in genotype frequencies caused by intrinsic and extrinsic...

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