Objectives To reveal causal level osteoarthritis (OA) disease biology by targeting regulatory interactions at GDF5. Methods By investigating different GDF5 regulatory regions (R2, R3-5, R7-R9, R18...

Since the 1960s, the Democratic Party has transformed. From a party rooted since the New Deal era in both “developmental liberalism” and a version of social democratic class politics, it has grown int...

Since the 1970s, the Democratic Party has realigned—a shift that might have cost Kamala Harris the White House.

Our ability to pinpoint causal variants using GWAS is dependent on understanding the dynamic epigenomic and epistatic context of each associated locus. Being the best studied skeletal locus, GDF5 asso...

Since the 1970s, the Democratic Party has realigned—a shift that might have cost Kamala Harris the White House.

PhD Project - MRC DiMeN Doctoral Training Partnership: Investigating the role of COLGALT2 in osteoarthritis using a stem cell model of cartilage health and disease at Newcastle University, listed on F...