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Christina Yap

@christinayap.bsky.social
230 followers 51 following 6 posts

Professor of Clinical Trials Biostatistics, The Institute of Cancer Research, UK

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Reposted by Christina Yap
ICR-CTSU @icr-ctsu.bsky.social · 27/03/2026
The OPTIMISE‑AR paper was published in @thelancetoncol.bsky.social last week. This introduces a practical toolkit to support the analysis and visualisation of patient‑reported outcomes (PROs) in early‑phase dose‑finding oncology trials. 🧪
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Christina Yap @christinayap.bsky.social · 24/01/2026
Delighted to share OPTIMISE-ROR – recommendations to help embed patient-reported outcomes (PROs) more meaningfully in dose-finding oncology trials. It sets out core PRO objectives to support tolerability assessment, dose selection, and PRO strategy for subsequent studies. tinyurl.com/45thervu.
tinyurl.com
International Consensus-Driven Recommendations for Patient-Reported Outcome Research Objectives in Early Phase Dose-Finding Oncology Trials: OPTIMISE-ROR - PubMed
This foundational guidance outlines key PRO research objectives in DFOTs. By facilitating the systematic integration of PROs, this guidance supports the utilization of patient-centered evidence for the tolerability and efficacy assessment of therapies to inform dose escalation, optimization, and reg …
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Reposted by Christina Yap
Academy of Medical Sciences @acmedsci.bsky.social · 15/08/2025
Congratulations to Cross-Sector Experience Award recipient @christinayap.bsky.social 🎉 Through this award Prof Yap will work with AstraZeneca & Bayer to improve the design of early-phase trials, ensuring they are more effective & impactful for patients. 👉 bit.ly/45a0VWy #CrossSector @icr.ac.uk
Professor Christina Yap, Academy Cross-Sector Experience Awardee, next to a quote that reads: "I’m thrilled to collaborate with AstraZeneca and Bayer through placements, advancing statistical methods to improve early-phase trials and patient-centred outcomes."
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Christina Yap @christinayap.bsky.social · 19/05/2025
A real pleasure running this workshop with you and Devin Peipert - thank you so much! Had such an engaging and interactive group too!
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Christina Yap @christinayap.bsky.social · 13/05/2025
Thank you for the kind invitation to share insights on the value of PROs in phase I dose-finding trials. A fantastic conference in the beautiful city of Barcelona - I’ve learnt so much too! Such a privilege to be part of it!
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Christina Yap @christinayap.bsky.social · 18/01/2025
Passionate about cancer trials, patient-reported outcomes (PROs) & innovative methods? Join the Early Phase and Adaptive Trials Group at @icr-ctsu.bsky.social @icrlondon.bsky.social for an exciting undergraduate summer scholarship in early phase trials & PROs! Deadline: 26/01/25 shorturl.at/1h565
icr.ac.uk
Undergraduate Summer Scholarship Scheme - The Institute of Cancer Research, London
Our paid undergraduate summer scholarships offer undergraduate students a chance to gain hands-on cancer research experience.
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