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Chris Whelan

@chrisdwhelan.bsky.social
365 followers 236 following 31 posts

Very infrequent Bluesky poster. Interested in population proteomics, genetics, neuroscience & biomarker development. 🇮🇪🧠🧬

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Chris Whelan @chrisdwhelan.bsky.social · 16/09/2026
Today we announced the Atlas of Proteomic Technologies (APT), available at aptatlas.org. APT compares six proteomics technologies (Alamar, Biognosys, Nomic, Olink, Seer, Somalogic) across ten dimensions. We describe the resource in this pre-print: biorxiv.org/content/10.64898/2026.09.10.750723v1
biorxiv.org
Atlas of Proteomic Technologies: an evidence-based framework for selecting and combining commercial proteomics platforms
High-throughput proteomics now spans several technologies that differ in biological breadth, precision, specificity, sensitivity, cost, and method(s) of quantification; however, investigators currentl...
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Chris Whelan @chrisdwhelan.bsky.social · 10/01/2025
I'm delighted to announce that the Pharma Proteomics Project will commence full-scale proteomic profiling of the UK Biobank in 2025. We have selected the Olink Proteomics Explore HT platform and Ultima Genomics UG 100 sequencers for this unprecedented study. www.ukbiobank.ac.uk/learn-more-a...
ukbiobank.ac.uk
Launch of world’s most significant protein study set to usher in new understanding for medicine
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Reposted by Chris Whelan
Veera Rajagopal @doctorveera.bsky.social · 12/12/2024
Association of polygenic scores for neuropsychiatric traits with self-reported professions based on analysis of 420k individuals from UK Biobank and Million Veteran Program. Look at the 'arts & design' category. Artistic talent comes at a cost--a piece of your mind :)
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Reposted by Chris Whelan
Eric Topol @erictopol.bsky.social · 11/12/2024
Could be combined in the future with a continuous sensor (implant) for real-time detection of proteins driving inflammation in high-risk individuals www.science.org/doi/10.1126/... @science.org
science.org
Active-reset protein sensors enable continuous in vivo monitoring of inflammation
Continuous measurement of proteins in vivo is important for real-time disease management and prevention. Implantable sensors for monitoring small molecules such as glucose have been available for more...
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Reposted by Chris Whelan
Jochen Schwenk @jochwenk.bsky.social · 21/11/2024
Here we tried to provide some objective views to the reoccurring discussion: pubs.acs.org/doi/10.1021/... The key is to understand the biases and factors causing the differences in the data. Those can include and do go beyond the antibodies.
pubs.acs.org
The Circulating Proteome─Technological Developments, Current Challenges, and Future Trends
Recent improvements in proteomics technologies have fundamentally altered our capacities to characterize human biology. There is an ever-growing interest in using these novel methods for studying the ...
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Chris Whelan @chrisdwhelan.bsky.social · 20/11/2024
Loved participating in the ‘Advancing Multi-Omics to the Clinic’ meeting in beautiful Sydney this week. Fascinating talks from several KOLs (see photos for Ruedi Aebersold’s revised Central Dogma of Biology) & lots of encouraging interplay between mass spectrometry and affinity-based proteomics.
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