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Chris Weston

@chris-west0n.bsky.social
537 followers 799 following 4 posts

Biochemist, liver poker, immune cell tinkerer, fibroblast fiddler, macrophage meddler. University of Birmingham.

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Reposted by Chris Weston
Prof Sheena Cruickshank @sheencr.bsky.social · 10/10/2026
This is shameful. The controversial Guinea-Bissau truck RFKJr wants to fund has been given ahead. Now a life saving vaccine will be deliberately withheld from newborns in a country where hep B is endemic
theguardian.com
Controversial vaccine trial touted by RFK Jr gets go-ahead in Guinea-Bissau
Recommended dose of hepatitis B vaccine will be withheld from thousands of newborns by Danish researchers
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Prof Sheena Cruickshank @sheencr.bsky.social · 20/05/2026
“If your neighbour’s house is on fire, you don’t wait and watch. You help to put it out before the fire spreads to yours. That’s the interconnected world we live in, and an important lesson for all politicians watching the crisis unfold.” Excellent from @profdevisridhar.bsky.social
theguardian.com
Ebola in the DRC needs the world’s attention now – if your neighbour’s house is on fire, you don’t wait and watch | Devi Sridhar
In the interconnected world we live in the west can’t afford to turn away, says Devi Sridhar, chair of global public health at the University of Edinburgh
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Alexander Dent @follicular.bsky.social · 12/05/2026
🧪 Very cool. I never knew before that KRAS was such a tough target for drugs-- a greasy ball as they say in the piece. www.nytimes.com/2026/05/12/h...
nytimes.com
How an ‘Impossible’ Idea Led to a Pancreatic Cancer Breakthrough
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Reposted by Chris Weston
Prof Sheena Cruickshank @sheencr.bsky.social · 16/11/2025
This is fucking terrifying. In one meeting acip could shatter access to multiple vaccines by attacking adjuvants, childhood vaccines schedule and hepatitis B
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Dr. Sabine Hurka @hurkasabine.bsky.social · 21/09/2025
Today, I say goodbye to an old friend—the #Biochemical #Pathways poster. It has hung in countless labs and offices, including on my own wall while I was studying #bioinformatics, inspiring my fascination with life’s chemistry. #science #legacy #Roche 💔💔💔
roche.com
Roche | Biochemical Pathways
Biochemical Pathways provide an overview of the chemical reactions of cells in various species and organs.
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Reposted by Chris Weston
Jacky Goetz @goetzjacky.bsky.social · 23/01/2025
This is wild 🤩 www.nature.com/articles/s41...
nature.com
Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature
Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.
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Reposted by Chris Weston
Chise @sailorrooscout.bsky.social · 02/01/2025
THIS IS HUGE! Researchers at Stanford Medicine have devised an influenza vaccine that prompts immunity to ALL four major flu subtypes AND shows potential against bird flu, indicating a significant advancement in flu prevention and a potential increase in vaccine efficacy. Let’s talk about that! 🧪🧵⬇️
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Thiago Carvalho @cyrilpedia.bsky.social · 26/12/2024
'Here, we show that this reagent appears to be unreliable due to providing false-positive signals at the expected molecular weight of Bax in immunoblotting experiments and likewise provides false-positive signals in immunofluorescence-based detection of Bax expression' www.nature.com/articles/s41...
nature.com
Why Bax detection in >1400 publications might be flawed - Cell Death & Disease
Cell Death & Disease - Why Bax detection in >1400 publications might be flawed
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Reposted by Chris Weston
Prof Sheena Cruickshank @sheencr.bsky.social · 20/12/2024
This is really disappointing- only 41.8% of eligible people have taken up the offer of an RSV vaccine! London has the lowest take up- 34.2%. Takeup in some ethnic groups such as S Asian as low as 14.3%- this clearly stores MUCH more work needed to communicate about this vaccine & its benefits 🧪
gov.uk
RSV vaccine coverage report in older adults for catch-up cohorts in England: November 2024
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Reposted by Chris Weston
Fionna O’Leary @fascinatorfun.bsky.social · 18/12/2024
Goldman Sachs analysts : The money men saying the quiet part out loud Curing patients may not be a sufficiently profitable enterprise for biotech companies. Chronic disease is a far more beneficial business model www.cnbc.com/2018/04/11/g...
cnbc.com
Goldman Sachs asks in biotech research report: 'Is curing patients a sustainable business model?'
Goldman Sachs warns sales from the most successful disease treatments are difficult to maintain.
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Oded Rechavi @odedrechavi.bsky.social · 19/12/2024
Sure, we can send you our dat
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Reposted by Chris Weston
CholestasisDoc @cholestasisdoc.bsky.social · 14/12/2024
New work from us: Oral vancomycin is associated with attenuation in IBD activity in people with PSC. We also studied changes in gut microbiome profile, and key transcriptomic and metabolomic features. academic.oup.com/ecco-jcc/adv...
academic.oup.com
Open label vancomycin in primary sclerosing cholangitis-inflammatory bowel disease: improved colonic disease activity and associations with changes in host-microbiome-metabolomic signatures
AbstractBackground. We conducted a single-arm interventional study, to explore mucosal changes associated with clinical remission under oral vancomycin (OV
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Ahmed Elsharkawy @ahmedelsharkawy.bsky.social · 25/11/2024
www.bbc.com/news/article... Nice to see Debbie Shawcross (not on here yet!), @drgautammehta.bsky.social and others really highlighting this issue on various BBC platforms today! #LiverSky @adhanda.bsky.social @aleksanderkrag.bsky.social
bbc.com
‘At 31, I was told if I didn’t stop drinking, I could die’
BBC journalist Hazel Martin was told she had liver fibrosis and must go teetotal or she could die.
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Elisa Granato @prokaryota.bsky.social · 19/11/2024
me (weighing chemicals): it says here the compound can be "a bit static-y" lol i'm sure it's fine my spatula:
cute seal covered in snow/ice looking up at the camera with a look of desperation
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Sophie Acton @actonlab.bsky.social · 19/11/2024
Beautiful paper from Burkhard Ludewig’s group showing the importance of immunoregulatory stroma to support anti-tumour immunity. www.cell.com/action/showP...
cell.com
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Reposted by Chris Weston
Angie Rasmussen @angierasmussen.bsky.social · 19/11/2024
I spoke to @mscribe.bsky.social @theguardian.com about the H5N1 case in BC. More and more human cases are occurring, along with mutations that indicate further human adaptation. We need to treat these cases like a warning, because that is what they are. www.theguardian.com/world/2024/n...
theguardian.com
Bird flu in Canada may have mutated to become more transmissible to humans
Scientists are racing to understand what a hospitalized teen’s case of bird flu may mean for future outbreaks
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