iiinova — where your digital self keeps evolving

Reposted by Junhong Choi

MSKEducation @mskeducation.bsky.social · 25/09/2026

Want to learn more about Brendan's research? Check out Brendan's award-winning 2025 MSK Postdoc Slam presentation, which earned him both 1st Place and the People's Choice Award! 🏆🥇 youtu.be/q56F_Sru_PM?...

youtu.be

MSK Postdoc Slam 2025

YouTube video by Memorial Sloan Kettering Cancer Center

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Reposted by Junhong Choi

MSKEducation @mskeducation.bsky.social · 25/09/2026

Meet #MSKPostdoc Brendan Camellato from the @choijunhong.bsky.social Lab. Brendan is developing tools for “molecular recording”, giving cells the ability to capture the key events that shape both healthy development and the progression of diseases like cancer. #NPAW2026 🇨🇦

#BestPartOfScience: Constantly learning how the
world works and contributing, even in small ways,
to our shared understanding. Basic science may
not directly cure disease, but it lays the
foundation for every biomedical breakthrough.

#BecomingAScientist: I was fascinated by both how much we know about life at the cellular and molecular level and how much remains to be discovered. That curiosity led me to a career in science.

#CareerAdvice: Science is a creative pursuit.
Make time to step away from the bench and let
your mind wander. Some of the best ideas emerge
when you're not actively searching for them.

#FunFact: Playing drums helps me to think
creatively, and to think in the moment,
improvising when needed while always looking
a little bit ahead at what’s coming next.

Brendan Camellato, PhD
Choi Lab

National Postdoc Appreciation Week
September 2026

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Vijay Ramani @vram142.bsky.social · 14/09/2026

Everything you wanted to know about single-molecule epigenomics but were too afraid to ask! Wonderful to co-write (h/t ENORMOUS lift by @arnaudkr.bsky.social) this primer on our nascent field. Also, a 💯 example of wonderful colleagues building something *together*, not in competition =)

nature.com

A practical guide to studying genome function using single-molecule genomics

Nature Reviews Molecular Cell Biology - Single-molecule genomics methods are used to study the activity of regulatory factors on individual DNA molecules genome-wide, thereby enabling...

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Reposted by Junhong Choi

Erik van Nimwegen @erikvannimwegen.bsky.social · 27/08/2026

Want to explore and understand the structure of your single-cell omics or other high-dimensional data? Try Bonsai! www.nature.com/articles/s41... Check out our tutorial videos with 1. Highlights of the Bonsai-scout exploratory analysis tool: www.youtube.com/watch?v=TE7T...

youtube.com

Bonsai-scout: Highlights

YouTube video by ISMARA: inferring gene regulatory interactions

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Nozomu Yachie @nzmyachie.bsky.social · 04/09/2026

Maybe it’s time to say goodbye to UMAP and other low-dimensional embeddings (at least in many single-cell analyses). We developed MILK to encode single-cell populations into tree representations at unprecedented scales. www.biorxiv.org/content/10.6... Here’s what MILK is: 🧵

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cxqiu.bsky.social @cxqiu.bsky.social · 09/04/2026

New preprint @cxqiu.bsky.social @jshendure.bsky.social ! Can we learn regulatory grammars of human cell types — by training on mouse development and transferring across 241 mammalian genomes? Introducing STEAM & a whole-organism scATAC-seq atlas from E10 to birth. www.biorxiv.org/content/10.6...

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cxqiu.bsky.social @cxqiu.bsky.social · 04/11/2025

Thrilled to share I’ve started my lab at Dartmouth’s Geisel School of Medicine! We focus on mapping cellular trajectories & TF networks in development and Mendelian disorders, exploring new therapies. Join us—postdocs, grads, and scientists welcome! sites.dartmouth.edu/qiulab/

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Jay Shendure @jshendure.bsky.social · 14/10/2025

Super excited about first Shendure/Baker Lab collaboration & preprint on a multiplex sequencing-based strategy for screening de novo proteome editors in mammalian cells. Kudos to the brilliant Chase Suiter (not here) & @greenahn.bsky.social on the work! Preprint here: www.biorxiv.org/content/10.1...

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Memorial Sloan Kettering Cancer Center @mskcancercenter.bsky.social · 24/06/2025

🎉 Congrats to MSK postdoc research scholar Dr. Brendan Camellato for being named a 2025 @jcchildsfund.bsky.social ‬ Research Fellow! His work will focus on how cell signaling drives #stemcell differentiation with single-cell resolution. #JCCFellow

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Junhong Choi @choijunhong.bsky.social · 24/06/2025

Congrats Brendan Camellato for his Jane Coffin Childs Fellowship!! 🎉🎉

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Reposted by Junhong Choi

Sternberg Lab @sternberglab.bsky.social · 28/05/2025

We're thrilled to share the published version of our DRT9 story, online today @nature.com! Congratulations to all authors! www.nature.com/articles/s41...

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Junhong Choi @choijunhong.bsky.social · 06/05/2025

Very grateful to receive the Searle Scholars Award, especially during this challenging time! This support will help our lab realize our vision of genomic recording for reconstructing the mammalian cell fate decision. searlescholars.org/2025/04/14/s...

searlescholars.org

SEARLE SCHOLARS PROGRAM NAMES 15 SCIENTISTS AS SEARLE SCHOLARS FOR 2025

Members of the new class of Searle Scholars pursue ground-breaking research in chemistry and the biomedical sciences. Each receives an award of $300,000 in flexible funding to support his, her, or …

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Junhong Choi @choijunhong.bsky.social · 06/05/2025

Happy to share our new review on molecular circuits for genomic recording with @chenomics.bsky.social! Here, we present our views on the remaining challenges in the field of genomic recording for reconstructing cell-fate decisions. (1/2)

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Caleb Lareau @caleblareau.bsky.social · 14/03/2025

Trying a slightly new model (for us at least) of #openscience. With @ronanchaligne.bsky.social and @karolisk.bsky.social, we pitted 10x Genomics Chromium GEM-X against Illumina PIPseq V head-to-head to understand these two platforms for single-cell genomics. Some thoughts off the bleeding edge: /1

media.tenor.com

a baby is eating a piece of food while sitting on the ground .

ALT: a baby is eating a piece of food while sitting on the ground .

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Naama Aviram @naamaaviram.bsky.social · 02/01/2025

New year, new beginnings! 🎉 The Aviram Lab will officially open its doors on March 1st @mskcancercenter.bsky.social! We’ll study microbial immune systems and their connection to fundamental cellular processes like #RNA transcription and #DNA integrity. #NewPI #AcademicSky #WomenInSTEM (1/2)

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AndreaVentura @andreaventura.bsky.social · 18/12/2024

🧪1/ 🚨New paper on ecDNAs from our lab! We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! Let’s dive in! 🧵👇 www.nature.com/articles/s41...

nature.com

Engineered extrachromosomal oncogene amplifications promote tumorigenesis - Nature

Large extrachromosomal DNAs are engineered using a CRISPR- and Cre–loxP-based approach and shown to drive cancer in mouse models, with potential applications in determining the role of oncogene a...

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Carl Zimmer @carlzimmer.com · 25/11/2024

Imagine a mouse in which all 10 billion cells keep a diary from fertilization. Imagine sentinel cells recording your experiences and sending out dispatches in the form of DNA. Here's a story I wrote about cell recorders 🧪 Gift link: nyti.ms/3Z3Mqza

nyti.ms

‘DNA Typewriters’ Can Record a Cell’s History

Labs around the world are trying to turn cells into autobiographers, tracking their own development from embryos to adults.

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The Elowitz Lab at Caltech @elowitzlab.bsky.social · 25/11/2024

"The lives of cells, recorded"--our new review on genomic recording systems and how they can reveal the dynamics of multicellular development. A pleasure to work on this with amazing colleagues from the Allen Discovery Center for Cell Lineage Tracing. www.nature.com/articles/s41...

nature.com

The lives of cells, recorded - Nature Reviews Genetics

Recent advances in genome engineering are enabling the recording of cellular histories into genomes, with single-cell and spatial omics technologies enabling their reconstruction into cellular lineage...

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Vijay Ramani @vram142.bsky.social · 15/11/2024

The latest from our group, led by Megan Ostrowski and @martyyang.bsky.social, is now published in final form (www.cell.com/cell/fulltex...! Many thanks to our excellent peer reviewers for suggesting several experiments (including CAF-1 perturbation) to really improve the study =) #epigenetics

cell.com

The single-molecule accessibility landscape of newly replicated mammalian chromatin

By developing a long-read sequencing method to simultaneously map replication status and protein-DNA contacts in cells, Ostrowski, Yang, et al. show that newly replicated chromatin is enriched for unw...

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Junhong Choi @choijunhong.bsky.social · 14/11/2024

New synthetic biology / genomic recording lab opening in the New York city! Please reach out via choij10 _at_ mskcc.org if you are interested in joining / collaborating! Mskcc.org/research/ski/labs/junhong-choi

mskcc.org

The Junhong Choi Lab

The Choi Lab develops new synthetic biology tools to study cell-fate decisions in development.

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