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Chiara Stringari

@chiarastringari.bsky.social
764 followers 1.9K following 32 posts

Scientist at @cnrs.bsky.social @laboptbio.bsky.social lob.ip-paris.fr/en/chiara-stringari Label-free optical microscopy and metabolic imaging. 'Science doesn't care about what you believe'

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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 08/09/2026
Next LOB seminar is by Anna Letizia Allegra Mascaro from LENS - European Laboratory for Non-linear Spectroscopy When: Thursday September 10th 11h00 Where: LOB Meeting room Bldg 84 Title : In vivo imaging of cortical dynamics in autism lob.ip-paris.fr/agenda/semin...
lob.ip-paris.fr
Seminar of Anna Letizia Allegra Mascaro - European Laboratory for Non-Linear Spectroscopy
11:00am, Ecole Polytechnique, LOB Meeting room Bldg 84
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Chiara Stringari @chiarastringari.bsky.social · 03/09/2026
The program is now available! Register before October 1st to the International School “Multiphoton and multiharmonic microscopy for the life sciences: principles and applications” Venice, Italy - January 18 to 22, 2027. Program and registration here: www.unige.ch/multiphotonv...
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Reposted by Chiara Stringari
Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 25/08/2026
Resonant third harmonic generation in biological pigments Dees et al, APL Photonics 2026 doi.org/10.1063/5.03... A new article from @laboptbio.bsky.social microscopy unit @cnrs.fr @inserm.fr @xpolytechnique.bsky.social @ipparis.bsky.social (1/5)
doi.org
Resonant third harmonic generation in biological pigments
Third harmonic generation (THG) microscopy provides label-free structural contrast of biological tissues. While the THG process can be enhanced by electronic tr
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Chiara Stringari @chiarastringari.bsky.social · 15/07/2026
Do you still have trouble exporting raw FLIM data from @leicamicrosystems.bsky.social and analyzing them with #OpenSource software? Good news! A very clear, step-by-step protocol has just been published by Jason E. Lee's lab. bio-protocol.org/en/bpdetail?...
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 25/06/2026
Last week, on June 18, the Laboratoire d'Optique et Biosciences (LOB) at École Polytechnique celebrated its 25th anniversary! Many thanks to all our institutional partners— @xpolytechnique.bsky.social at @ipparis.bsky.social, @cnrs.fr and @inserm.fr —for attending this event.
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Chiara Stringari @chiarastringari.bsky.social · 18/06/2026
The slides of the Rencontres du GDR Imabio 2026, Workshop A3 : « Two-photon excited fluorescence lifetime metabolic imaging », held at the Laboratory for Optics and Biosciences with #XiaotongYuan and #IlseChauvet are in this repository: zenodo.org/records/2074... @gdrimabio.bsky.social
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 12/06/2026
As part of the workshops offered during the event "Journées du @gdrimabio.bsky.social GDR Imabio", discover advanced microscopy techniques with researchers from the Laboratory of Optics and Biosciences
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 10/06/2026
A new paper from the LOB microscopy unit on high-speed multiphoton light-sheet imaging has been published in Optica. We achieved kilohertz frame rates by enhancing the signal-to-photodamage ratio during live imaging. doi.org/10.1364/OPTI...
doi.org
Radware Captcha Page
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Chiara Stringari @chiarastringari.bsky.social · 30/05/2026
Edgar Morin ou l’éloge de la complexité www.lemonde.fr/disparitions...
lemonde.fr
Edgar Morin ou l’éloge de la complexité
Révolté contre la pensée réductrice, Edgar Morin, mort vendredi 29 mai, s’est attaché à enseigner la « complexité » de tout phénomène, prenant en compte son processus d’engrenage ou ses réactions cont...
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Chiara Stringari @chiarastringari.bsky.social · 30/05/2026
The next level of artificial intelligence: "A multi-agent system for automating scientific discovery" www.nature.com/articles/s41...
nature.com
A multi-agent system for automating scientific discovery - Nature
Nature - A multi-agent system for automating scientific discovery
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Chiara Stringari @chiarastringari.bsky.social · 05/05/2026
We are pleased to announce that the School on Multiphoton and Multiharmonic Microscopy for the Life Sciences: Principles and Applications will take place in Venice, Italy from January 18 to 22, 2027, www.unige.ch/multiphotonv...
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 07/04/2026
Caroline Boudoux, Professor at @polymtl.bsky.social and entrepreneur will give the next LOB seminar: "It Goes without Saying: Taking the Guesswork of Your PhD in Engineering" See you on April 17th at 11AM in Amphi Becquerel. lob.ip-paris.fr/en/events/se...
lob.ip-paris.fr
Seminar of Caroline Boudoux - Professor at Polytechnique Montréa et an entrepreneure (Castor Optics)
11:00am, Ecole Polytechnique, Amphi Becquerel
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 18/03/2026
Félicitations à Gaël Latour pour la brillante soutenance de son Habilitation à Diriger des Recherches (HDR) intitulée : « Cornée, parchemin, vernis : la microscopie avancée comme outil d'investigation » !
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 23/02/2026
For the next LOB seminar @joergenderlein.bsky.social from Georg August University in Göttingen will present : “Fluorescence-Lifetime Super-Resolution Microscopy”. See you on February 26th at 11:00am in Amphi Becquerel. lob.ip-paris.fr/en/events/se...
lob.ip-paris.fr
Seminar of Jörg ENDERLEIN, Institute of Physics – Biophysics, Georg August University
11:00am, Ecole Polytechnique, Amphi Becquerel
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 23/02/2026
Exciting science and discussion during the "Young Lobsters Day" (19/02) - Des discussions scientifiques passionnantes pendant le "Young Lobsters Day" (19/02)
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 05/02/2026
Next LOB seminar: 12 Feb. 2026, 11:00AM, @xpolytechnique.bsky.social, Amphi Becquerel Seminar of @lorenaguilarlab.bsky.social from UNAM Title: Metabolic State as a Regulator of Transcriptional Dynamics in Human Embryonic Stem Cell Differentiation lob.ip-paris.fr/en/events/se...
lob.ip-paris.fr
Seminar of Lorena Aguilar-Arnal, CInstituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México-UNAM Mexico
11:00am, Ecole Polytechnique, Amphi Becquerel
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 23/01/2026
📢 LOB Seminars are back! 🗓 29 Jan 2026 | 11:00am 📍 Amphi Poisson 🎤 Baptiste Blochet (Saint-Pérès Paris Institute for the Neurosciences – SPPIN) “Multiplexed Phase Imaging: From Laser Metrology to Super-Resolution Microscopy” Looking forward to seeing you there! lob.ip-paris.fr/en/events/se...
lob.ip-paris.fr
Seminar of Baptiste Blochet - Saint-Peres Paris Institute for the Neurosciences (SPPIN)
11:00am, Ecole Polytechnique, Amphi POISSON
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Chiara Stringari @chiarastringari.bsky.social · 07/01/2026
Our paper “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue” is published in @commsbio.nature.com, thanks to an exciting collaboration between @laboptbio.bsky.social and @institutducerveau.bsky.social www.nature.com/articles/s42...
nature.com
Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue - Communications Biology
Multimodal label-free nonlinear microscopy and advanced image analysis map single-cell metabolism and myelin dynamics in live cerebellar tissue during demyelination, supporting research in neuroinflam...
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Reposted by Chiara Stringari
SPIE @spie.org · 10/12/2025
💡 New guidelines aim to standardize label-free optical metabolic imaging, a technique that uses light to study cell metabolism without dyes. Consistency could lead to more accurate, reproducible results in cancer & drug development research. Read the #SPIE_JBO article: bit.ly/4isPMFc
Optical redox ratio coded images from a cervical epithelial tissue.
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 09/12/2025
L'équipe de microscopie avancée du @laboptbio.bsky.social adossée à la platforme Morphoscope du noeud Ile-de France-Sud de @france-bioimaging.bsky.social, est à la recherche d'un IR en bioimage informatique. emploi.cnrs.fr/Offres/MOBIN...
emploi.cnrs.fr
Portail Emploi CNRS - Offre d'emploi - Ingénieur-e en bio-imagerie computationnelle H/F
Prendre en charge la gestion de données de bio-imagerie obtenues lors d'expériences de microscopie multimodale : stockage, gestion, analyse automatisée et visualisation ainsi que ingénierie logicielle des outils développés.
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 28/11/2025
Congratulations to Poncia Nyembo Kasongo on the brilliant defense of his PhD thesis "Second Harmonic Generation Imaging of the Structure of Healthy and Pathological Corneas" !
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Reposted by Chiara Stringari
Elisabeth Bik @elisabethbik.bsky.social · 09/11/2025
This is the result of a meeting held this summer in Stockholm, organized by the Royal Swedish Academy of Sciences, where I was one of the attendees. Proposed actions against fake science presented after meeting www.kva.se/en/news/prop...
Screenshot of the article linked to in the post. It shows the headline and some introductionary text: 
"Proposed actions against fake science presented after meeting
Today, Dan Larhammar, Uppsala University and former president of the Academy, and Bernhard Sabel from Otto von Guericke University in Magdeburg, Germany, have published the Stockholm Declaration, which outlines a number of proposed countermeasures against fake science, often produced by AI. This growing problem was discussed early this summer at a workshop held at the Royal Swedish Academy of Sciences."

Below that a group photo of the attendees on the steps of the main building of the Royal Swedish Academy.
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Reposted by Chiara Stringari
Elisabeth Bik @elisabethbik.bsky.social · 09/11/2025
More press @FinancialTimes [Gift link]: A tide of fabricated research risks scientific integrity Manipulation, disinformation and fakery could lead to a knowledge collapse www.ft.com/content/a1c6...
ft.com
A tide of fabricated research risks scientific integrity
[FREE TO READ] Manipulation, disinformation and fakery could lead to a knowledge collapse
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Reposted by Chiara Stringari
Elisabeth Bik @elisabethbik.bsky.social · 09/11/2025
Reformation of science publishing: the Stockholm Declaration A call to action for universities, academies, science organizations and funders to unite and join this effort. Bernhard Sabel and Dan Larhammar royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org
Reformation of science publishing: the Stockholm Declaration | Royal Society Open Science
Science relies on integrity and trustworthiness. But scientists under career pressure are lured to purchase fake publications from ‘paper mills’ that use AI-generated data, text and image fabrication....
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Chiara Stringari @chiarastringari.bsky.social · 17/11/2025
Excited to share that our international consensus guidelines for cellular, label-free optical metabolic imaging have been published in the Journal of Biomedical Optics. www.spiedigitallibrary.org/journals/jou... #metabolicimaging #labelfree
spiedigitallibrary.org
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Chiara Stringari @chiarastringari.bsky.social · 31/10/2025
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics www.nature.com/articles/s41...
nature.com
A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics - Nature Communications
l-lactate is a key metabolite supporting neuronal activity, but methods to monitor l-lactate dynamics alongside neuronal activity in vivo have been limited. Here, authors report R-eLACCO2.1, a red flu...
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Reposted by Chiara Stringari
Ignacio Izeddin @izeddinresearch.bsky.social · 22/10/2025
Wrapping up #Mifobio2025! What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years! Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr
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Chiara Stringari @chiarastringari.bsky.social · 16/10/2025
Here you can find the slides of the MIFOBIO 2025 Workshop "A-07 Analyzing FLIM data for metabolic imaging applications with Phasor Analysis" using FLUTE software, with Xiaotong Yuan. zenodo.org/records/1736... #mifobio2025
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Chiara Stringari @chiarastringari.bsky.social · 15/10/2025
Amazing talk on “Mechanobiology of the Mitotic Spindle” by @ivatolic.bsky.social at #mifobio2025 @gdrimabio.bsky.social
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Laboratory for Optics and Biosciences @laboptbio.bsky.social · 09/10/2025
(2025/10/08) Congratulations to @chiarastringari.bsky.social on the defense of her Habilitation à Diriger les Recherches (HDR) "Label-free multimodal non-linear optical microscopy for functional imaging of living tissues" !
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Chiara Stringari @chiarastringari.bsky.social · 03/09/2025
Over a decade at @laboptbio.bsky.social at @polytechniqueparis.bsky.social !
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Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025
Happy to finally publish this work… Congrats authors and thanks funders @agencerecherche.bsky.social #FondationBettencourtSchueller‬‬‬
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Reposted by Chiara Stringari
Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025
These findings help to establish THG microscopy as a quantitative, multiscale imaging technique, paving the way for new applications. 📖 #Neuroscience #Myelin #THG #Microscopy #Research
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Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025
Fun fact for multiphoton microscopy geeks: aberrations caused by vertical micro-interfaces appear to be a significant contrast mechanism in polarized THG imaging. 😎
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Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025
Finally, we illustrate the relevance of pTHG microscopy for characterizing myelin distribution at different scales in fixed mouse and human brain tissue.
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Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025
Our study presents a systematic characterization of polarized THG (pTHG) signals from individual axons, enabling the derivation of myelin scores in various systems. 🐭🐟 We confirm the sensitivity of THG for myelin in mouse tissue and detect early axon development in zebrafish.
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Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025
We show that axons exhibit complex pTHG profiles that depend on axon morphology and can't be explained by classical models. We establish a numerical strategy to relate pTHG profiles to axon diameter and myelin thickness, taking into account myelin-induced optical aberrations.
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Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025
Multiscale characterization of myelin distribution with polarized THG microscopy Morizet et al, Optica 2025 doi.org/10.1364/OPTI... @laboptbio.bsky.social @institutducerveau.bsky.social @cnrs.fr ‪‪ @ip-paris.bsky.social @inserm.fr (1/8)
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Emmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025
By #J_Morizet #N_Olivier #MS_Aigrot #P_Mahou #E_Martin #A_Desmazieres #B_Stankoff @chiarastringari.bsky.social 🔬🌟 Find out how Third Harmonic Generation (THG) microscopy could help advance myelin biomedical research! 🧠
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Laboratory for Optics and Biosciences @laboptbio.bsky.social · 11/07/2025
Congratulations to Amelie Elouin on her brilliant defence of her PhD thesis, entitled 'Investigating the role of Myosin II in collective cell migration during gastrulation in the zebrafish Danio rerio' !
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Chiara Stringari @chiarastringari.bsky.social · 01/07/2025
Congratulations @caporalclement.bsky.social And it was an honor to have you at LOB!
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Falk Schneider @faldalf.bsky.social · 15/06/2025
Excited to be in Genoa for the #WeberSymposium2025 A few days of all fun things fluorescence ahead 🔬🎆🌈 Starting out with an account of the seminal contributions by Gregorio Weber presented by the amazing Dave Jameson
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Chiara Stringari @chiarastringari.bsky.social · 15/06/2025
The talk "Fluorescence Lifetime Microscopy (FLIM) for label-free metabolic imaging of living tissues" given at the #VirtualPub of @eurobioimaging.bsky.social is now online! #FLIM www.youtube.com/watch?v=WC1V...
youtube.com
Fluorescence Lifetime Microscopy (FLIM) for label-free metabolic imaging of living tissues
YouTube video by Euro-BioImaging Communication
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Reposted by Chiara Stringari
Chris B. Schaffer @chris-schaffer.bsky.social · 23/04/2025
Scientist colleagues, write to your hometown paper and tell folks about your work, what motivates it, and what impact it could have. Aim for publication June 16.
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Laboratory for Optics and Biosciences @laboptbio.bsky.social · 09/04/2025
Congratulations to Stella Dees for defending her thesis on "Multicontrast 3P-microscopy for biological tissue imaging"
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Reposted by Chiara Stringari
Laboratory for Optics and Biosciences @laboptbio.bsky.social · 07/04/2025
Congratulation to Giulia Galante for her thesis defense about the "Characterization and physico-chemical monitoring of collagen degradation in parchments by polarization-resolved multiphoton microscopy!
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Institute of Neurodegenerative Diseases @imn-bordeaux.bsky.social · 26/03/2025
📰 New article published in @nature.com entitled "A human brain map of mitochondrial respiratory capacity and diversity" 🧠 An international research team has created a map revealing the diversity of #mitochondrial phenotypes in the human #brain ✒️ By @micheltds.bsky.social and all 📌 For more ⬇️
nature.com
A human brain map of mitochondrial respiratory capacity and diversity - Nature
The ability to physically partition the human brain at a spatial resolution comparable to neuroimaging methods enabled the development of a brain-wide atlas of mitochondrial content, specialization an...
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