Chiara Stringari @chiarastringari.bsky.social · 08/10/2026Physics is everywhere #Berlin 31st @picoquant.bsky.social International Workshop 020
Chiara Stringari @chiarastringari.bsky.social · 06/10/2026LAST PLACES AVAILABLE for the International School: Multiphoton and multiharmonic microscopy for the life sciences: principles and applications 122
Reposted by Chiara StringariNobel Prize @nobelprize.org · 05/10/2026BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.” 241077515
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 08/09/2026Next LOB seminar is by Anna Letizia Allegra Mascaro from LENS - European Laboratory for Non-linear Spectroscopy When: Thursday September 10th 11h00 Where: LOB Meeting room Bldg 84 Title : In vivo imaging of cortical dynamics in autism lob.ip-paris.fr/agenda/semin...lob.ip-paris.frSeminar of Anna Letizia Allegra Mascaro - European Laboratory for Non-Linear Spectroscopy11:00am, Ecole Polytechnique, LOB Meeting room Bldg 84 021
Chiara Stringari @chiarastringari.bsky.social · 03/09/2026The invited speaker lineup includes: Emmanuel Beaurepaire, Paolo Bianchini, Giulio Cerullo, Liangyi Chen, Alberto Diaspro, Peter Friedl, François Légaré, Francesco Pavone, Robert Prevedel, Cristina Rodríguez, Pieter Vanden Berghe, Chris Xu, Sixian You 000
Chiara Stringari @chiarastringari.bsky.social · 03/09/2026Covered topics are Multi-photon microscopy, Second and Third-Harmonic generation, Three-photon microscopy, Laser sources, Adaptive optics, Temporal focusing, Super-resolution microscopy, Neuroscience and Cancer applications. #Multiphoton #Microscopy #Multiharmonics #LifeSciences 110
Chiara Stringari @chiarastringari.bsky.social · 03/09/2026Italian Society for Pure and Applied Biophysics (SIBPA) and Istituto Veneto di Scienze Lettere ed Arti The School brings together an exciting mix of lectures, short talks, posters, and networking opportunities. 100
Chiara Stringari @chiarastringari.bsky.social · 03/09/2026The program is now available! Register before October 1st to the International School “Multiphoton and multiharmonic microscopy for the life sciences: principles and applications” Venice, Italy - January 18 to 22, 2027. Program and registration here: www.unige.ch/multiphotonv... 162
Reposted by Chiara StringariEmmanuel Beaurepaire @ebeaurepaire.bsky.social · 25/08/2026Resonant third harmonic generation in biological pigments Dees et al, APL Photonics 2026 doi.org/10.1063/5.03... A new article from @laboptbio.bsky.social microscopy unit @cnrs.fr @inserm.fr @xpolytechnique.bsky.social @ipparis.bsky.social (1/5)doi.orgResonant third harmonic generation in biological pigmentsThird harmonic generation (THG) microscopy provides label-free structural contrast of biological tissues. While the THG process can be enhanced by electronic tr 1135
Chiara Stringari @chiarastringari.bsky.social · 15/07/2026This workflow will make it much easier for Leica FLIM users to adopt a reproducible, transparent, and free analysis pipeline. Thanks to Jason E. Lee and colleagues for making advanced FLIM data analysis more accessible to the microscopy community! #FLIM #Phasor #OpenSource 030
Chiara Stringari @chiarastringari.bsky.social · 15/07/2026The protocol describes every step required to: -export raw FLIM data from Leica Microsystems, -perform phasor analysis using FLUTE, a free and open-source software for fluorescence lifetime imaging analysis. 💻 FLUTE (GitHub): github.com/LaboratoryOp...github.comGitHub - LaboratoryOpticsBiosciences/FLUTE: Fluorescence Lifetime Ultimate Explorer (FLUTE) is a GUI for exploring and analyzing Fluorescence Lifetime Microscopy (FLIM) dataFluorescence Lifetime Ultimate Explorer (FLUTE) is a GUI for exploring and analyzing Fluorescence Lifetime Microscopy (FLIM) data - LaboratoryOpticsBiosciences/FLUTE 000
Chiara Stringari @chiarastringari.bsky.social · 15/07/2026Do you still have trouble exporting raw FLIM data from @leicamicrosystems.bsky.social and analyzing them with #OpenSource software? Good news! A very clear, step-by-step protocol has just been published by Jason E. Lee's lab. bio-protocol.org/en/bpdetail?... 273
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 25/06/2026Last week, on June 18, the Laboratoire d'Optique et Biosciences (LOB) at École Polytechnique celebrated its 25th anniversary! Many thanks to all our institutional partners— @xpolytechnique.bsky.social at @ipparis.bsky.social, @cnrs.fr and @inserm.fr —for attending this event. 1112
Chiara Stringari @chiarastringari.bsky.social · 18/06/2026The slides of the Rencontres du GDR Imabio 2026, Workshop A3 : « Two-photon excited fluorescence lifetime metabolic imaging », held at the Laboratory for Optics and Biosciences with #XiaotongYuan and #IlseChauvet are in this repository: zenodo.org/records/2074... @gdrimabio.bsky.social 031
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 12/06/2026As part of the workshops offered during the event "Journées du @gdrimabio.bsky.social GDR Imabio", discover advanced microscopy techniques with researchers from the Laboratory of Optics and Biosciences 192
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 10/06/2026A new paper from the LOB microscopy unit on high-speed multiphoton light-sheet imaging has been published in Optica. We achieved kilohertz frame rates by enhancing the signal-to-photodamage ratio during live imaging. doi.org/10.1364/OPTI...doi.orgRadware Captcha Page 1116
Chiara Stringari @chiarastringari.bsky.social · 30/05/2026Edgar Morin ou l’éloge de la complexité www.lemonde.fr/disparitions...lemonde.frEdgar Morin ou l’éloge de la complexitéRévolté contre la pensée réductrice, Edgar Morin, mort vendredi 29 mai, s’est attaché à enseigner la « complexité » de tout phénomène, prenant en compte son processus d’engrenage ou ses réactions cont... 010
Chiara Stringari @chiarastringari.bsky.social · 30/05/2026The next level of artificial intelligence: "A multi-agent system for automating scientific discovery" www.nature.com/articles/s41...nature.comA multi-agent system for automating scientific discovery - NatureNature - A multi-agent system for automating scientific discovery 011
Chiara Stringari @chiarastringari.bsky.social · 05/05/2026With Luigi Bonacina (Université de Genève) and Margaux Bouzin (Università degli Studi di Milano-Bicocca) we curated a lineup of international speakers, who are among the leading experts in the field. www.unige.ch/multiphotonv...unige.chSpeakers - multiphotonvenice2027 - UNIGE 010
Chiara Stringari @chiarastringari.bsky.social · 05/05/2026The school will host 50–70 PhD students and early-career researchers, offering a focused and interactive learning environment. Pre-registration is now open! Please note that participation is limited, and the registration deadline is October 1, 2026. We hope to see you in Venice! 010
Chiara Stringari @chiarastringari.bsky.social · 05/05/2026We are pleased to announce that the School on Multiphoton and Multiharmonic Microscopy for the Life Sciences: Principles and Applications will take place in Venice, Italy from January 18 to 22, 2027, www.unige.ch/multiphotonv... 384
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 07/04/2026Caroline Boudoux, Professor at @polymtl.bsky.social and entrepreneur will give the next LOB seminar: "It Goes without Saying: Taking the Guesswork of Your PhD in Engineering" See you on April 17th at 11AM in Amphi Becquerel. lob.ip-paris.fr/en/events/se...lob.ip-paris.frSeminar of Caroline Boudoux - Professor at Polytechnique Montréa et an entrepreneure (Castor Optics)11:00am, Ecole Polytechnique, Amphi Becquerel 032
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 18/03/2026Félicitations à Gaël Latour pour la brillante soutenance de son Habilitation à Diriger des Recherches (HDR) intitulée : « Cornée, parchemin, vernis : la microscopie avancée comme outil d'investigation » ! 051
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 23/02/2026For the next LOB seminar @joergenderlein.bsky.social from Georg August University in Göttingen will present : “Fluorescence-Lifetime Super-Resolution Microscopy”. See you on February 26th at 11:00am in Amphi Becquerel. lob.ip-paris.fr/en/events/se...lob.ip-paris.frSeminar of Jörg ENDERLEIN, Institute of Physics – Biophysics, Georg August University11:00am, Ecole Polytechnique, Amphi Becquerel 083
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 23/02/2026Exciting science and discussion during the "Young Lobsters Day" (19/02) - Des discussions scientifiques passionnantes pendant le "Young Lobsters Day" (19/02) 0111
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 05/02/2026Next LOB seminar: 12 Feb. 2026, 11:00AM, @xpolytechnique.bsky.social, Amphi Becquerel Seminar of @lorenaguilarlab.bsky.social from UNAM Title: Metabolic State as a Regulator of Transcriptional Dynamics in Human Embryonic Stem Cell Differentiation lob.ip-paris.fr/en/events/se...lob.ip-paris.frSeminar of Lorena Aguilar-Arnal, CInstituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México-UNAM Mexico11:00am, Ecole Polytechnique, Amphi Becquerel 031
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 23/01/2026📢 LOB Seminars are back! 🗓 29 Jan 2026 | 11:00am 📍 Amphi Poisson 🎤 Baptiste Blochet (Saint-Pérès Paris Institute for the Neurosciences – SPPIN) “Multiplexed Phase Imaging: From Laser Metrology to Super-Resolution Microscopy” Looking forward to seeing you there! lob.ip-paris.fr/en/events/se...lob.ip-paris.frSeminar of Baptiste Blochet - Saint-Peres Paris Institute for the Neurosciences (SPPIN)11:00am, Ecole Polytechnique, Amphi POISSON 032
Chiara Stringari @chiarastringari.bsky.social · 07/01/2026Congratulations to all the authors @baharasadipour.bsky.social Joséphine Morizet @remironzano.bsky.social Xingjian Zhang Aigrot Marie-Stéphane Pierre Mahou Xavier Solinas @MinhSonPHAN Minh Son PHAN @anatolechessel.bsky.social Bruno Stankoff Anne Desmazieres @ebeaurepaire.bsky.social 030
Chiara Stringari @chiarastringari.bsky.social · 07/01/2026Our label-free multimodal imaging approach combines THG myelin imaging, NAD(P)H FLIM, and advanced automated analysis to simultaneously quantify myelin architecture and cellular metabolism in living brain tissue, revealing cell-specific metabolic signatures and changes during demyelination. 130
Chiara Stringari @chiarastringari.bsky.social · 07/01/2026Our paper “Label-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue” is published in @commsbio.nature.com, thanks to an exciting collaboration between @laboptbio.bsky.social and @institutducerveau.bsky.social www.nature.com/articles/s42...nature.comLabel-free nonlinear microscopy probes cellular metabolism and myelin dynamics in live tissue - Communications BiologyMultimodal label-free nonlinear microscopy and advanced image analysis map single-cell metabolism and myelin dynamics in live cerebellar tissue during demyelination, supporting research in neuroinflam... 1149
Reposted by Chiara StringariSPIE @spie.org · 10/12/2025💡 New guidelines aim to standardize label-free optical metabolic imaging, a technique that uses light to study cell metabolism without dyes. Consistency could lead to more accurate, reproducible results in cancer & drug development research. Read the #SPIE_JBO article: bit.ly/4isPMFc 031
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 09/12/2025L'équipe de microscopie avancée du @laboptbio.bsky.social adossée à la platforme Morphoscope du noeud Ile-de France-Sud de @france-bioimaging.bsky.social, est à la recherche d'un IR en bioimage informatique. emploi.cnrs.fr/Offres/MOBIN...emploi.cnrs.frPortail Emploi CNRS - Offre d'emploi - Ingénieur-e en bio-imagerie computationnelle H/FPrendre en charge la gestion de données de bio-imagerie obtenues lors d'expériences de microscopie multimodale : stockage, gestion, analyse automatisée et visualisation ainsi que ingénierie logicielle des outils développés. 042
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 28/11/2025Congratulations to Poncia Nyembo Kasongo on the brilliant defense of his PhD thesis "Second Harmonic Generation Imaging of the Structure of Healthy and Pathological Corneas" ! 071
Reposted by Chiara StringariElisabeth Bik @elisabethbik.bsky.social · 09/11/2025This is the result of a meeting held this summer in Stockholm, organized by the Royal Swedish Academy of Sciences, where I was one of the attendees. Proposed actions against fake science presented after meeting www.kva.se/en/news/prop... 0193
Reposted by Chiara StringariElisabeth Bik @elisabethbik.bsky.social · 09/11/2025More press @FinancialTimes [Gift link]: A tide of fabricated research risks scientific integrity Manipulation, disinformation and fakery could lead to a knowledge collapse www.ft.com/content/a1c6...ft.comA tide of fabricated research risks scientific integrity[FREE TO READ] Manipulation, disinformation and fakery could lead to a knowledge collapse 1165
Reposted by Chiara StringariElisabeth Bik @elisabethbik.bsky.social · 09/11/2025Reformation of science publishing: the Stockholm Declaration A call to action for universities, academies, science organizations and funders to unite and join this effort. Bernhard Sabel and Dan Larhammar royalsocietypublishing.org/doi/10.1098/...royalsocietypublishing.orgReformation of science publishing: the Stockholm Declaration | Royal Society Open ScienceScience relies on integrity and trustworthiness. But scientists under career pressure are lured to purchase fake publications from ‘paper mills’ that use AI-generated data, text and image fabrication.... 38144
Chiara Stringari @chiarastringari.bsky.social · 17/11/2025Grateful for the collaborative efforts of our global team and the progress this represents for the field. A special thank to Irene Georgakoudi for leading this work. 010
Chiara Stringari @chiarastringari.bsky.social · 17/11/2025Excited to share that our international consensus guidelines for cellular, label-free optical metabolic imaging have been published in the Journal of Biomedical Optics. www.spiedigitallibrary.org/journals/jou... #metabolicimaging #labelfreespiedigitallibrary.org 141
Chiara Stringari @chiarastringari.bsky.social · 31/10/2025A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics www.nature.com/articles/s41...nature.comA red fluorescent genetically encoded biosensor for in vivo imaging of extracellular l-lactate dynamics - Nature Communicationsl-lactate is a key metabolite supporting neuronal activity, but methods to monitor l-lactate dynamics alongside neuronal activity in vivo have been limited. Here, authors report R-eLACCO2.1, a red flu... 021
Reposted by Chiara StringariIgnacio Izeddin @izeddinresearch.bsky.social · 22/10/2025Wrapping up #Mifobio2025! What I love most about this conference is how it reminds me that science is, above all, a collaborative effort. Nothing beats the sense of community here. See you in 2 years! Check the Imabio @gdrimabio.bsky.social website for course and seminar replays soon imabio-cnrs.fr 1255
Chiara Stringari @chiarastringari.bsky.social · 16/10/2025Here you can find the slides of the MIFOBIO 2025 Workshop "A-07 Analyzing FLIM data for metabolic imaging applications with Phasor Analysis" using FLUTE software, with Xiaotong Yuan. zenodo.org/records/1736... #mifobio2025 1114
Chiara Stringari @chiarastringari.bsky.social · 15/10/2025Amazing talk on “Mechanobiology of the Mitotic Spindle” by @ivatolic.bsky.social at #mifobio2025 @gdrimabio.bsky.social 2122
Reposted by Chiara StringariLaboratory for Optics and Biosciences @laboptbio.bsky.social · 09/10/2025(2025/10/08) Congratulations to @chiarastringari.bsky.social on the defense of her Habilitation à Diriger les Recherches (HDR) "Label-free multimodal non-linear optical microscopy for functional imaging of living tissues" ! 0144
Chiara Stringari @chiarastringari.bsky.social · 03/09/2025Over a decade at @laboptbio.bsky.social at @polytechniqueparis.bsky.social ! 090
Reposted by Chiara StringariEmmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025Happy to finally publish this work… Congrats authors and thanks funders @agencerecherche.bsky.social #FondationBettencourtSchueller 051
Reposted by Chiara StringariEmmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025These findings help to establish THG microscopy as a quantitative, multiscale imaging technique, paving the way for new applications. 📖 #Neuroscience #Myelin #THG #Microscopy #Research 151
Reposted by Chiara StringariEmmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025Fun fact for multiphoton microscopy geeks: aberrations caused by vertical micro-interfaces appear to be a significant contrast mechanism in polarized THG imaging. 😎 1123
Reposted by Chiara StringariEmmanuel Beaurepaire @ebeaurepaire.bsky.social · 16/07/2025Finally, we illustrate the relevance of pTHG microscopy for characterizing myelin distribution at different scales in fixed mouse and human brain tissue. 131