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NSF C-GEM

@cgemcci.bsky.social

554 followers 173 following 56 posts

U.S. National Science Foundation Center for Genetically Encoded Materials (NSF C-GEM). Re-engineering the ribosome to create a fundamentally new form of chemical matter. (CHE-2503885 and 2002182). #NSFfunded Find us online at www.gem-net.net

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NSF C-GEM @cgemcci.bsky.social · 03/09/2026

🎈 Come visit C-GEM's booth at the Kits Cubed STEM Fair in Oakland, CA, on Saturday, September 12th! Learn more about the FREE event: www.eventbrite.com/e/kits-cubed...

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NSF C-GEM @cgemcci.bsky.social · 30/06/2026

🔬 Curious about careers at national labs? Join us on Thu, July 16 @ 1-2p Pacific Time for a virtual Career Chat with Dr. Emily Hoff and Dr. Hannah Dedmon. RSVP: airtable.com/app9pcujvcmD...

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NSF C-GEM @cgemcci.bsky.social · 12/09/2025

🎈 Come visit C-GEM's table to learn about polymer science at the Cambridge Science Carnival on Sunday, September 21, 2025! Find out more about the free event here: cambridgesciencecarnival.org

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NSF C-GEM @cgemcci.bsky.social · 10/05/2025

🎉 To celebrate the 75th anniversary of the NSF, the Centers for Chemical Innovation collected thank-you notes from our members that highlight the positive impact of NSF support. 🎈 Read the thank-you notes here: www.nsfcci.org/nsf75 #NSFfunded

A header in gold and silver text that reads "NSF 75 years of discovery & innovation" Below that is an open envelope with a piece of paper sticking out. On the paper in a handwritten font reads, "Thank you, NSF!" and below the text are the logos of the following NSF centers: C-CAS, CSN, CSOE, MONET, CSP, CMCC, and C-GEM.

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NSF C-GEM @cgemcci.bsky.social · 05/12/2024

📰 Hot off the press at @naturecomms.bsky.social: RNA language models predict mutations that improve RNA function www.nature.com/articles/s41... Congrats to @kshulgina.bsky.social @jhdcate.bsky.social and coauthors on a great C-GEM + @innovativegenomics.bsky.social collaboration! #NSFfunded #RNAsky

A red ribosome in front of a figure showing the phylogenetic relationships between organisms in GARNET with information on growth temperatures and ribosome sequences

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NSF C-GEM @cgemcci.bsky.social · 12/08/2024

✨ New from C-GEM: Ribosomal Synthesis of Ketone-containing Peptide Backbone via O to C Acyl Shift Congrats to Carly, Helena, former undergrads Isaac and Hana, Matt, and Alanna! #chemsky #NSFfunded chemrxiv.org/engage/chemr...

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NSF C-GEM @cgemcci.bsky.social · 17/01/2024

DEADLINE EXTENDED! Apply for the C-GEM Summer Undergraduate Research Program by February 12th! Spend your summer doing research in a C-GEM lab - stipend/housing/travel provided. Great for students with an interest in chemistry, biochem, chem bio, synbio, and more! gem-net.net/join/undergrads

See threaded tweet for screen-readable PDF

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NSF C-GEM @cgemcci.bsky.social · 16/01/2024

This work has now been published in Nucleic Acids Research! Congrats to Tent and all of the authors! doi.org/10.1093/nar/...

A figure describing the workflow for this manuscript. The left side of the figure represents the design of a minimal PTC by citizen scientists and shows a ribbon diagram of the miniPTC construct in 3D. Below that, cartoon people are manipulating larger-than-life screens from the Eterna video game. One person is designing an RNA in the puzzle interface. Two people are looking at the voting interface. The right side of the slide describes analysis of the minimal PTC in three bullet points: secondary and tertiary structure, substrate binding, and fragment reaction. Below this is a cartoon person holding a giant pipette above some eppendorf tubes in a rack.

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NSF C-GEM @cgemcci.bsky.social · 30/11/2023

Over the past year, we've been working with Eterna to use the game as a teaching aid to reinforce important biochemical concepts. We're excited to share the first two modules: "introduction to RNA" and "the ribosome and translation" - available now! www.coursera.org/learn/rna-bi...

Cartoon image of the Eterna game interface showing a cursor hovering over an RNA stem loop. In the background, a more complex Eterna puzzle is blurred.

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NSF C-GEM @cgemcci.bsky.social · 15/11/2023

Looking for an undergrad summer research opportunity in chemistry, biochem, or chem bio? Check out C-GEM SURP! SURP Scholars spend 10 weeks in a C-GEM lab and participating in professional development. Stipend + housing + travel provided. Apply by Feb 1! gem-net.net/join/undergr...

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NSF C-GEM @cgemcci.bsky.social · 08/11/2023

New preprint from C-GEM! #NSFfunded Incorporation of multiple beta 2-backbones into a protein in vivo using an orthogonal aminoacyl-tRNA synthetase Another fantastic collab with Schrödinger - congrats to Noah, Ara, and Alanna!! www.biorxiv.org/content/10.1...

Image shows a beta-2-hydroxy-boc-lysine highlighting the extended backbone and hydroxy moiety going into an E. coli cell, where it becomes a blue dot, charged onto a red cartoon tRNA using the red cartoon enzyme MaPylRS. Subsequently, the ribosome is able to incorporate this blue beta-2-hydroxy-boc-lysine monomer into a protein.

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