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Alex Carll, PhD, MSPH

@cardiocarll.bsky.social
25 followers 24 following 14 posts

Associate Professor of physiology passionately studying how environmental stressors harm the heart. Environmental cardiologist. 🔥 🫁 🧠🫀

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Reposted by Alex Carll, PhD, MSPH
University of Louisville Christina Lee Brown Envirome Institute @uoflenvirome.bsky.social · 15/06/2026
Can cooling ingredients in e-cigarettes cause irregular heartbeat or cardiac arrest? Envirome's @cardiocarll.bsky.social weighs in with the latest research on the impact of synthetic cooling ingredients in e-cigarettes. newsroom.heart.org/news/can-coo... @cardiometabosci.bsky.social
newsroom.heart.org
Can cooling ingredients in e-cigarettes cause irregular heartbeat or cardiac arrest?
Research Highlights: Adding cooling ingredients to e-cigarettes resulted in mis-timed heartbeats that could increase the risk for sudden cardiac arrest, according to a study conducted in mice and in l...
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Reposted by Alex Carll, PhD, MSPH
Center For Cardiometabolic Science @cardiometabosci.bsky.social · 19/06/2026
Cooling additives in e-cigs aren’t harmless. New work from the Carll Lab shows synthetic coolants (WS‑3, WS‑23) ↑ autonomic imbalance and trigger ventricular arrhythmias—independent of nicotine. Implication: “ice” flavors may elevate cardiac risk beyond nicotine alone. #Vaping #Cardiosky
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Reposted by Alex Carll, PhD, MSPH
@amybisinthewoods.bsky.social 🍄🍄‍🟫 @amybdogsandfungi.bsky.social · 05/06/2026
We have to end his power in November. It is life or death.
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Reposted by Alex Carll, PhD, MSPH
Nature @nature.com · 03/06/2026
Scientists are raising the alarm about a White House proposal that could fundamentally recast federally funded science. The proposed rules would put political appointees in control of all federal grants and de-emphasize peer review, among other measures. go.nature.com/4ucZgsk
go.nature.com
White House proposes vast overhaul of US science funding: what you need to know
The Trump administration’s proposal aims to improve transparency in federal funding, but critics fear the proposed rules would politicize research
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Reposted by Alex Carll, PhD, MSPH
Nature Portfolio @natureportfolio.nature.com · 22/04/2026
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Reposted by Alex Carll, PhD, MSPH
Center For Cardiometabolic Science @cardiometabosci.bsky.social · 26/03/2026
Congratulations to Dr. Brittany Reynolds, a former Trainee in the Laboratory of Dr. Alex Carll, who received the Paper of the Year Award from the Cardiovascular Toxicology Specialty Section of the Society of Toxicology at their recent annual meeting.
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 26/03/2026
Really proud of Dr. Ramalingam for not only generating but also demystifying this very complicated dataset. Wishing he had been able to visit from Hungary to receive this honor at SOT in person himself.
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Reposted by Alex Carll, PhD, MSPH
Center For Cardiometabolic Science @cardiometabosci.bsky.social · 17/03/2026
Next, at the Society of Toxicology conference, on Tuesday afternoon, Dr. Brittany Reynolds, a former PhD student in the Laboratory of Dr. Alex Carll, will present her thesis research showing that beta-blockade prevents e-cigarette-induced arrhythmias during and after pregnancy.#Toxicology#SOT2026
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Reposted by Alex Carll, PhD, MSPH
Nature @nature.com · 23/01/2026
Thirteen of the US NIH’s advisory councils, which must review grant applications before funding is awarded, are on track to have no voting members go.nature.com/4r6TiIp
go.nature.com
Exclusive: key NIH review panels due to lose all members by the end of 2026
Thirteen of the agency’s advisory councils, which must review grant applications before funding is awarded, are on track to have no voting members.
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Reposted by Alex Carll, PhD, MSPH
Nature @nature.com · 22/01/2026
US federal agencies were gutted in 2025, losing ~20% of their staff relative to 2024.
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Reposted by Alex Carll, PhD, MSPH
Scientific American @sciam.bsky.social · 14/01/2026
Global warming surpassed 1.5 degrees Celsius for the past three years, meaning Earth is currently on track to breach the Paris climate agreement by the end of the decade
scientificamerican.com
2025 Wasn’t the Hottest Year on Record. Earth Is Still Barreling to the Climate Brink
Global warming surpassed 1.5 degrees Celsius for the past three years, meaning Earth is currently on track to breach the Paris climate agreement by the end of the decade
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 14/01/2026
While Louisville has plenty of room for improvement, its cycling infrastructure is one of the features I truly appreciate here. I eagerly await my daily bike commutes once I graduate from elementary school taxi driver.
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Reposted by Alex Carll, PhD, MSPH
Center For Cardiometabolic Science @cardiometabosci.bsky.social · 08/01/2026
Congratulations to Helen E. Collins on receiving the 2025 International Union of Physiological Sciences International Early-Stage Faculty Prize for her contributions to Physiology. Read more about the award at www.iups.org/academy/awards #cardiosky
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 05/01/2026
Out just in time for New Years' resolutions to quit puffing! Our review of how e-cigs and e-cig constituents cause arrhythmia. journals.physiology.org/doi/abs/10.115… @ciehs.bsky.social @cardiometabosci.bsky.social @uoflenvirome.bsky.socialjournals.physiology.org/doi/abs/10.1...25
journals.physiology.org
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Reposted by Alex Carll, PhD, MSPH
brian_delisle @bpdelisle.bsky.social · 09/11/2025
🚨🆕🧪🔬on 💓🕒 Delisle et al. 😉show the circadian clock gene BMAL1 drives sex-specific daily patterns in cardiac ion channels ⚡️❤️‍🔥 in 🐭, shaping when arrhythmias may strike in males vs females 🧠➡️❤️ #Circadian #Physiology #Heart #Arrhythmia #Sex #Science #Cardiosky www.sciencedirect.com/science/arti...
sciencedirect.com
BMAL1 mediates sex-specific circadian regulation of cardiac ion channels and temporal arrhythmia vulnerability
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 28/10/2025
Congrats to Brittany Reynolds of @cardiometabosci.bsky.social for successfully defending her dissertation today! Way to represent the team with a straightforward talk and meaningful insights how e-cig exposures evoke arrhythmias! Now to get this last cherry on the top submitted and published!
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 27/10/2025
Today’s nanosecond pause in the news cycle 🥱 is a great excuse to hop on over to the AJP-Heart podcast about Brittany Reynolds’ concerning findings that vaping may increase postpartum arrhythmias 😱 E-cigs Promote Arrhythmias During Labor and Postpartum www.podbean.com/ew/pb-9t76s-...
podbean.com
E-cigs Promote Arrhythmias During Labor and Postpartum
In our latest episode, Associate Editor Dr. Jason Carter (Baylor University, Robbins College of Health and Human Sciences) interviews authors Dr. Alex Carll and Brittany Reynolds (University of Louisv...
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Reposted by Alex Carll, PhD, MSPH
CardioOB @cardioob.bsky.social · 25/10/2025
Pregnancy-Related CV Complications Are High & Rising @emilyswlau.bsky.social @drklindley.bsky.social @abraguo.bsky.social #CardioObstetrics #ACCRepOB #ACCCardioOB @accintouch.bsky.social 🔗: www.acc.org/Latest-in-Ca... @ahajournals.bsky.social 🔗: www.ahajournals.org/doi/10.1161/...
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Reposted by Alex Carll, PhD, MSPH
Nature Portfolio @natureportfolio.nature.com · 15/10/2025
A single dose of psilocybin reduced pain, pain-induced anxiety and depression-like behaviors in mice, according to a study published in Nature Neuroscience. 🧪
go.nature.com
Single-dose psilocybin rapidly and sustainably relieves allodynia and anxiodepressive-like behaviors in mouse models of chronic pain - Nature Neuroscience
Hammo et al. show that a single dose of psilocybin rapidly and sustainably relieves both chronic pain and anxiodepressive-like behaviors in mice by restoring prefrontal activity through partial agonism at 5-HT2A and 5-HT1A receptors.
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 02/10/2025
Recent interview about cardiopulmonary risks of vaping: UofL scientist and physician discuss the health effects of e-cigarettes Q&A with Alex Carll and Rodrigo Cavallazzi @uoflenvirome.bsky.social @cardiometabosci.bsky.social @ciehs.bsky.social www.uoflnews.com/section/scie...
uoflnews.com
UofL scientist and physician discuss the health effects of e-cigarettes | UofL News
Many people believe that electronic cigarettes are less harmful than traditional cigarettes, but research at the University of Louisville School of Medicine has shown that electronic cigarettes have a...
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Reposted by Alex Carll, PhD, MSPH
Center For Cardiometabolic Science @cardiometabosci.bsky.social · 09/09/2025
Don’t go vaping my heart, especially when pregnant💨 🫀🤰 Want to know why? Find out more in the latest publication by the Alex Carll, PhD, lab in AJP-Heart, led by PhD student, Brittany Reynolds. journals.physiology.org/doi/abs/10.1...
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 30/04/2025
Proud of Anand Ramalingam for coalescing this data to show repeat e-cigarette exposure transiently evokes arrhythmias via the beta1 adrenoceptor, consistently increases BP, changes the cardiac proteome, and persistently depresses HR and ventricular repolarization. www.ahajournals.org/doi/full/10....
ahajournals.org
Acute and Persistent Cardiovascular Effects of Menthol E‐Cigarettes in Mice | Journal of the American Heart Association
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 24/04/2025
Either the baristas at Heart Rhythm Society are superhuman, or they’re cheating. Either way, kudos #HRS2025
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Reposted by Alex Carll, PhD, MSPH
Soragni:Lab @alice.soragnilab.com · 18/03/2025
The NCI grant supporting the Columbia comprehensive cancer center was terminated. Tell me how terminating support for cancer research helps the economy. taggs.hhs.gov/Content/Data...
taggs.hhs.gov
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Reposted by Alex Carll, PhD, MSPH
Center For Cardiometabolic Science @cardiometabosci.bsky.social · 18/03/2025
Tomorrow at #SOT25, Brittany Reynolds, a PhD student in the lab of Dr. Alex Carll, will present her current research on the effects of maternal e-cigarette exposure on cardiac electrophysiology and arrhythmia susceptibility. @sotoxicology.bsky.social @cardiocarll.bsky.social
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Reposted by Alex Carll, PhD, MSPH
Center For Cardiometabolic Science @cardiometabosci.bsky.social · 16/03/2025
Tomorrow at #SOT25, Romith Paily, a student in the lab of Dr. Alex Carll, will present his current findings on the effects of heat stress on cardiac electrophysiology and arrhythmia susceptibility. @cardiocarll.bsky.social @sotoxicology.bsky.social
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Reposted by Alex Carll, PhD, MSPH
Helen Collins @drhelenecollin1.bsky.social · 22/02/2025
We need to make pregnancy and the postpartum period safe for all women. Currently, maternal mortality rates are at an all time high in the US. In order to make things safer, we need more funding, research, and representation. pubmed.ncbi.nlm.nih.gov/39832282/
pubmed.ncbi.nlm.nih.gov
Maternal cardiovascular research and education should be prioritized in the United States - PubMed
Maternal cardiovascular research and education should be prioritized in the United States
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Reposted by Alex Carll, PhD, MSPH
brian_delisle @bpdelisle.bsky.social · 22/02/2025
🚨🫀🔬 Little et al reveal cardiac fibroblasts as major producers of high molecular weight hyaluronan post-heart attack heart ❤️‍🩹 Driven by HAS2- this ECM component accumulates but doesn’t impact fibroblast function 👉 journals.physiology.org/doi/abs/10.1... #CardioSky #Physiology #Science
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Reposted by Alex Carll, PhD, MSPH
Center for Integrative Environmental Health Sciences (CIEHS) @ciehs.bsky.social · 21/02/2025
Interested in moving environmental health research to policy? Join us for the John P. Wyatt Environment and Health Symposium, hosted by the University of Kentucky Center for the Environment. Register now to attend online or in person: www.research.uky.edu/john-p-wyatt...
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Reposted by Alex Carll, PhD, MSPH
University of Louisville Christina Lee Brown Envirome Institute @uoflenvirome.bsky.social · 06/02/2025
"The Healing Power of Trees": Read about the groundbreaking Green Heart Louisville Project in the latest issue of The Nature Conservancy Magazine. Green Heart is the first clinical trial to test a greening intervention the same way new drugs are tested. @nature.org www.nature.org/en-us/magazi...
nature.org
The Healing Power of Trees: A tree planting project improves the peoples' health
Adding 8,000 trees to a neighborhood in Louisville, Kentucky, improves health conditions that are linked to heart disease, stroke and some types of cancer.
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Reposted by Alex Carll, PhD, MSPH
Nature Portfolio @natureportfolio.nature.com · 07/02/2025
Temperature-related deaths in European cities could increase by up to 50% by the end of the century in the absence of climate change-mitigation policies, totalling up to 2.3 million additional deaths, suggests a paper published in Nature Medicine. go.nature.com/4glnYzU 🧪
This is figure 3, which shows city-level net changes in temperature-related excess death rates for each warming level under scenario SSP3-7.0 and no adaption to heat.
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 03/02/2025
Taking Omega3s and VitD over three years slowed biological aging by 3-4 months when combined with exercise. @ciehs.bsky.social @uoflenvirome.bsky.social
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Reposted by Alex Carll, PhD, MSPH
Nature Portfolio @natureportfolio.nature.com · 29/01/2025
A muscle patch developed using stem cells can help to repair failing hearts without adverse effects, according to a paper in Nature. #Medsky 🧪
go.nature.com
Engineered heart muscle allografts for heart repair in primates and humans - Nature
Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques, leading to improved cardiac function and paving the way for human clinical trials.
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Reposted by Alex Carll, PhD, MSPH
Mother Jones @motherjones.com · 29/01/2025
The media has failed the public on a crucial matter: the derangement of Robert F. Kennedy Jr., writes @davidcorn.bsky.social. News reports often describe him as a vaccine skeptic when he is far more dangerous than that.
motherjones.com
The Madness of Robert F. Kennedy. Jr.
The depth of his extremism has not been fully conveyed to the public.
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Reposted by Alex Carll, PhD, MSPH
brian_delisle @bpdelisle.bsky.social · 28/01/2025
🚨🫀⏰ Delisle et al 😉 review circadian mechanisms and sudden cardiac death🧬 Day-night cycles in ion channel regulation and myocardial protection impact arrhythmia risk💓👉 www.jmcc-online.com/article/S002... #IonChannels #Circadian #CardioSky #Arrhythmias #Physiology
jmcc-online.com
Circadian influences on sudden cardiac death and cardiac electrophysiology
Cardiologists have analyzed daily patterns in the incidence of sudden cardiac death to identify environmental, behavioral, and physiological factors that trigger fatal arrhythmias. Recent studies have...
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Reposted by Alex Carll, PhD, MSPH
Nature @nature.com · 27/01/2025
An extra 2.3 million people in European cities could die as a result of extreme temperatures — both hot and cold — by the end of the century go.nature.com/42pFO1r
go.nature.com
Extreme heat will kill millions of people in Europe without rapid action
Climate models predict that the number of heat-related deaths could soar in cities over the coming century, even when efforts are made to keep people safe.
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Alex Carll, PhD, MSPH @cardiocarll.bsky.social · 27/01/2025
The thin silver lining of increasing job security for environmental health researchers may either tarnish or entirely evaporate over the next four years. Trump administration halts proposed EPA limits on PFAS pollution www.ehn.org/trump-admini...
ehn.org
Trump administration halts proposed EPA limits on PFAS pollution
The Trump administration has withdrawn an EPA proposal to restrict PFAS discharges from industrial sites, prompting concern from environmental advocates about health risks and regulatory gaps.Shannon ...
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