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Campden Instruments

@campdeninstruments.bsky.social
58 followers 29 following 92 posts

Life Science Product Manufacturer | Products for animal behaviour, vibratomes for electrophysiology & other translational scientific research 🧠🫀🫁 campdeninstruments.com

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Reposted by Campden Instruments
SfN Journals @sfnjournals.bsky.social · 07/06/2026
#eNeuro | Effect of Functionally Selective Dopamine D1 Receptor Agonists on Complex Cognitive Processes in a Rodent Touchscreen Operant Chamber Task doi.org/10.1523/ENEURO.0296-25.2026
Dopamine D1 receptor (D1R) signaling in the brain has been strongly implicated in multiple cognitive processes, with D1 agonists known to enhance performance. The development of functionally selective D1 agonists that differentially activate D1R-mediated cAMP versus β-arrestin signaling may offer precision therapy if we understand how signaling bias impacts integrated cognitive processes in complex tasks. We therefore examined the effects of two selective D1 agonists, 2-methyldihydrexidine (2MDHX) and PF-06256142 (PF), on a rodent touchscreen-based Trial-Unique Nonmatching-To-Location task. Primarily assessing both spatial working memory and pattern separation in adult male rats, this behavioral paradigm requires greater cognitive demands to maintain performance throughout the testing session, significantly increasing task complexity. Our results revealed an inverted U-shaped dose response curve for both compounds, aligning with our previously published work, but did not demonstrate marked improvement in task performance. Subjects treated with the mid-dose range (10, 100, and 1,000 nmol/kg) generally performed similarly to, or slightly below, vehicle treated subjects whereas the highest dose administered (10,000 nmol/kg) significantly reduced task performance and engagement. The behavioral effects were similar for PF and 2MDHX, suggesting that functional selectivity/bias (at least for the cAMP versus β-arrestin signaling pathways) was not a major factor in this cognitive task. In addition to providing new information about how D1 agonists might affect different aspects of cognition, our data underscores the importance of dose optimization and task structure and showcases the translational value of touchscreen-based paradigms when assessing potential cognitive enhancers.
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Campden Instruments @campdeninstruments.bsky.social · 16/03/2026
Introducing a new accessory for Campden Vibrating Microtomes: the Aeration Tube Assembly! 🫧 Maintaining proper oxygenation is crucial for preserving tissue viability during slicing. Our new bubbler delivers consistent aeration directly within the tissue bath. Check it out: tinyurl.com/32n5ksxc
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Campden Instruments @campdeninstruments.bsky.social · 13/03/2026
Less than two weeks to go! Don't forget to sign up, and share it to whoever you may think will be interested! 🧠
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Campden Instruments @campdeninstruments.bsky.social · 11/02/2026
Today, on the International Day of Women and Girls in Science, we celebrate the women who move science forward on a daily basis, often not getting the credit they deserve. Here’s to the women advancing life science today and to the girls who will transform it tomorrow. 💜
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Campden Instruments @campdeninstruments.bsky.social · 09/02/2026
What better way to honour International Epilepsy Day than being able to promote an event to highlight the innovative research being done to better understand epilepsy. Speaking at this webinar will be @garethmorris.bsky.social and Kate Connor! 🧠🧪🔬 Make sure to register!
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Reposted by Campden Instruments
Laetitia Mony @laetitiamony.bsky.social · 28/01/2026
If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd parisneuro.ovh
parisneuro.ovh
Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience
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Reposted by Campden Instruments
Cell Physiology Workshop Liverpool @cpw-liverpool.bsky.social · 24/01/2026
The 41st Cell Physiology Workshop will take place in Liverpool UK, from 17-28th August 2026. 🧪🔬🫀🧠🐌🦑 Sign-up below to register your interest in attending, and receive all the important details and updates. 👇🏼 #ionchannels #neuroskyence
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Campden Instruments @campdeninstruments.bsky.social · 26/01/2026
Some excitement to start the week! We have a new application note on adrenal gland slices! Written by Dr Gabriel Stölting, this note highlights what is needed to make slices from both mouse and human adrenal gland samples, and what you can study with them! Check it out here: tinyurl.com/4ev7b9zz
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Reposted by Campden Instruments
Nature @nature.com · 15/01/2026
Nature research paper: Predictive coding of reward in the hippocampus go.nature.com/49mB13V
go.nature.com
Predictive coding of reward in the hippocampus - Nature
Calcium imaging of mouse hippocampal neurons while mice learn a reward-based task over several weeks provides insight into the evolution of the hippocampal reward representation during extended periods of experience.
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Campden Instruments @campdeninstruments.bsky.social · 19/11/2025
Somehow, the last day of #SfN2025 is already here! If you haven't come by, you have to today! Whether you want to increase your translational cognitive testing capabilities, or have a need to slice fresh tissue (brain, spinal cord, organoids, etc) we may have solutions to make your life easier!
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Campden Instruments @campdeninstruments.bsky.social · 18/11/2025
Happy Day 3 at #SfN2025 from San Diego! The first two days have been packed with great discussions and exciting science! If you’re here at the meeting, come by our booth and check out the Bussey–Saksida Touchscreen Chamber. We’d love to show you what it can do and answer your questions. 👋🧠
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Campden Instruments @campdeninstruments.bsky.social · 17/11/2025
#SfN2025 Exhibition Day 2, we are ready for you! Yesterday was an absolute blast and we can't wait to meet more of you! If you are also here, make sure to stop by the @lafayetteic.bsky.social booth and say hi to @cassdeichsel.bsky.social! There may or may not be some great swag waiting for you.
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Campden Instruments @campdeninstruments.bsky.social · 11/11/2025
We are in the final stretch now before we will be in San Diego at #SfN2025! This week, we wanted to highlight a different application area that we don't discuss so often: research into neuromuscular diseases! From wheel running to tissue slicing, investigating all levels is necessary!
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Campden Instruments @campdeninstruments.bsky.social · 07/11/2025
At #SfN2025, learn how Campden Instruments can help you investigate Neurodegenerative Diseases via translational behavioural studies as well as precision tissue slicing of everything from post-mortem samples to patient derived organoids to better understand the mechanistic underpinnings of disease.
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Campden Instruments @campdeninstruments.bsky.social · 04/11/2025
At Campden Instruments, we unite cognitive testing with advanced precision tissue slicing, giving researchers the power to correlate behavioural changes in ageing to the cellular mechanisms of learning and memory. To learn more, come say hi at #SfN2025!
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Campden Instruments @campdeninstruments.bsky.social · 30/10/2025
The end of October means we are getting closer to the biggest Neuroscience conference of the year- #SfN2025! Our sales executive, Cassandra will be attending! If you want to make sure to meet her, why not schedule a meeting? Slots can be booked here: ow.ly/vFQu50XkiHE
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Campden Instruments @campdeninstruments.bsky.social · 22/10/2025
Hallo Heidelberg! This week we are thrilled to be at #EESOrgan learning about everything organoids! If you are here, make sure to stop by the World Precision Instruments stand to learn more about tools to measure TEER and the 9000SMZ vibrating microtome to slice whatever tissue you want!
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Campden Instruments @campdeninstruments.bsky.social · 14/10/2025
Did you know that you can also slice living organoids on a vibrating microtome? It is not the easiest, but is definitely feasible! To learn more, you can meet our sales executive at the #EESOrgan Meeting next week with our distributor, World Precision Instruments! Will we see you there?
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Campden Instruments @campdeninstruments.bsky.social · 10/10/2025
Today, on World Mental Health Day, we support researchers working to understand the brain and translate those insights into real-world impact: from preclinical discovery to clinical progress. Better science means better mental health for all. 💙 #WorldMentalHealthDay #TranslationalNeuroscience
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Campden Instruments @campdeninstruments.bsky.social · 02/10/2025
New series coming up where we highlight Bussey-Saksida Touchscreen Chamber tasks! First is the 4-Choice Gambling Task! This task is used to investigate decision-making which can be implicated in many neurological and psychiatric disorders. To learn more: lnkd.in/dCFcWc3Z
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Campden Instruments @campdeninstruments.bsky.social · 22/09/2025
Our latest application note, drumroll please, is on precision cut liver slices (PCLS)! Many thanks to Dr Ben Leaker for giving us insights into the how and why PCLS are a useful tool! If you are interested you can read the full application note here: campdeninstruments.com/downloads/ap...
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Campden Instruments @campdeninstruments.bsky.social · 18/09/2025
We're detoxing our feed with a new application note featuring a sample type we don't usually discuss. Can you guess what sample has been sectioned and what the application note is about from these fluorescent microscopy images? Comment your guess and see if you were right: ow.ly/2J9c50WYajn
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Campden Instruments @campdeninstruments.bsky.social · 08/09/2025
Any #neuroskyence researchers attending #IUPS2025 this week? @cassdeichsel.bsky.social will be joining npi electronic, @berndpe.bsky.social with the 9000SMZ vibratome! So if you are interested in slice electrophysiology, make sure to come stop by our booth!
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Campden Instruments @campdeninstruments.bsky.social · 01/09/2025
So many conferences! This week you will be able to find Campden and a 9000SMZ at the international congress of the Polish Neuroscience Society. We will be spending the week with our fantastic Polish distributor, Animalab. Make sure to come say hi to @cassdeichsel.bsky.social #PTBUN2025
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Campden Instruments @campdeninstruments.bsky.social · 18/08/2025
The next conference season of 2025 is here again! Next week you will be able to meet Campden Instruments in Luebeck at the European Biological Rhythms Society Congress! Make sure to come say hi to @cassdeichsel.bsky.social #EBRS2025 #Chronobiology #BiologicalClock #CircadianRhythm #SleepResearch
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Campden Instruments @campdeninstruments.bsky.social · 11/08/2025
The annual @cpw-liverpool.bsky.social starts today! The two-week course enables students to learn how to perform cutting-edge electrophysiology experiments. We are thrilled to support the course by providing a 9000SMZ vibratome. To learn more about the 9000SMZ: lnkd.in/e5QeiWp9
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Campden Instruments @campdeninstruments.bsky.social · 24/07/2025
Our new 9000SMZ vibratome is on tour! If you are at the #BCVS2025 meeting in Baltimore this week, make sure to stop by our sister company, @aurorascientific.bsky.social, stand to see the new model and to learn more about how to make the most physiologically relevant myocardial slices!
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Campden Instruments @campdeninstruments.bsky.social · 22/07/2025
Today is World Brain Day, a day that we at Campden prioritise! The day aims to highlight how important the brain is in overall health and increase understanding of disorders. This year's theme is brain health for all ages, demonstrating that disorders can occur to the brain at all stages of life.
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Campden Instruments @campdeninstruments.bsky.social · 14/07/2025
Last week we highlighted the final quality checks taking place on the first batch of the 9000SMZ vibrating microtomes, and today we are hitting another major milestone: the new models are being packed and prepared for shipping! To learn more about the 9000SMZ: shorturl.at/0bQd1
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Campden Instruments @campdeninstruments.bsky.social · 11/07/2025
Before it begins entering labs all around the world, final quality control checks of the new 9000SMZ vibrating microtome must take place. The last step in the process is to evaluate the z-axis deflection, which is crucial for good slices. Next step is packaging! To learn more: ow.ly/erm650WocCB
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Campden Instruments @campdeninstruments.bsky.social · 04/07/2025
Summer is here, so it is also time for summer students in the lab who need to learn lab tools quick! When designing the new interface and features of the new 9000SMZ vibratome, an easy-to-use interface was a priority. To learn more about the 9000SMZ: ow.ly/qsmc50WkY06
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Campden Instruments @campdeninstruments.bsky.social · 18/06/2025
Good morning @uclnpp.bsky.social! Campden is spending the day at the Neuroscience Symposium, and are eager to show off the new 9000SMZ vibrating microtome! If you are at the event today, make sure to stop by, try out the new interface, and discover how the new model can produce great brain slices!
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Campden Instruments @campdeninstruments.bsky.social · 16/06/2025
Want to get your hands on the new 9000SMZ vibrating microtome and learn more about all the new features? Well, all of those attending the @uclnpp.bsky.social Symposium this week can!
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Campden Instruments @campdeninstruments.bsky.social · 12/06/2025
You wouldn’t use the same cutting technique for a crusty baguette and soft sponge cake, so why would biological tissue be any different? To accommodate tissue variability and produce superior slices, our new 9000SMZ has the largest range of slicing parameters yet. To learn more: shorturl.at/sfkYJ
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Campden Instruments @campdeninstruments.bsky.social · 10/06/2025
Our latest Talking Science Interview is out now! Here we had the opportunity to speak with Jimena Ferraris from Stockholm University about her research looking into the role of TIDA neurons in prolactin secretion and lactation! Check out the full interview here: shorturl.at/wDYN3 #neuroskyence
shorturl.at
Talking Science with Jimena Ferraris DVM, PhD | Campden Instruments
The next edition of our Talking Science Interview Series is here! This month we are featuring Jimena Ferraris from Stockholm University! In this interview, Jimena discusses her current research, whic...
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Reposted by Campden Instruments
Marco A. Maximo Prado @maximoprado.bsky.social · 23/05/2025
This is finally out! Great collaboration with Andy Holmes @timbussey.bsky.social @lisasaksida.bsky.social and @touchscreencog.bsky.social @westernubrainscan.bsky.social trainees www.nature.com/articles/s41...
nature.com
Integrating optical neuroscience tools into touchscreen operant systems - Nature Protocols
This protocol extension enables researchers to integrate optically based manipulation and measurement techniques into their touchscreen experimental systems, focusing on optogenetic manipulation, fibe...
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Campden Instruments @campdeninstruments.bsky.social · 26/05/2025
New to slicing murine brains on a vibrating microtome (vibratome)? Then check out this video where Jimena Ferraris DVM, PhD of @stockholm-uni.bsky.social gives her trade secrets for the best possible slices. Give it a watch and stay tuned for her full interview! www.linkedin.com/feed/update/...
linkedin.com
Tips for the best brain slices from Jimena Ferraris DVM, PhD | Campden Instruments
Are you new to slicing murine brains using a vibrating microtome (vibratome)? Or do you have some students starting in the lab for a summer practical and will also need to learn how to slice? Then ref...
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Campden Instruments @campdeninstruments.bsky.social · 22/05/2025
Does the rhyme "righty tighty, lefty loosey" live in your head rent-free when you screw in screws? Unfortunately, it doesn't apply to our left-hand screws needed to secure the blade to the holder. To all of our vibratome users, check out this new rhyme, thanks to AI, to help avoid making mistakes!
Tips for securing blades to the blade holder: picture of the blade holder design on Campden Instruments vibratomes with arrows over the two screws that secure the blade. The left-handed thread screw must be twisted in a counter-clockwise direction which is different than standard screws.

To help people remember this we have come up with the following rhyme thanks to AI: 
Left screw has a backward thread-
Turn it wrong, you'll strip it dead.
Tight is counterclockwise there-
so, twist with care, and be aware!
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Campden Instruments @campdeninstruments.bsky.social · 16/05/2025
Good morning Munich! We are here at Munich Brain Day, #MBD2025 at @mpiforbi.bsky.social ! We are joined by npi electronic GmbH. npi distributes our vibratomes in Germany and are well known for their diverse electrophysiology solutions. If you are here, make sure to come upstairs and say hi! 🧠
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Campden Instruments @campdeninstruments.bsky.social · 14/05/2025
Good morning Montpellier! @cassdeichsel.bsky.social is set up and ready for #NeuroFrance2025 put on by @socneuro.bsky.social If you are interested in vibratomes, touchscreen chambers for rodents, tools to monitor circadian activity, and more - come stop by!
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Campden Instruments @campdeninstruments.bsky.social · 08/05/2025
Next week is going to be busy! @cassdeichsel.bsky.social will be attending two events! First she will be at @socneuro.bsky.social #NeuroFrance2025! Then she will be attending @mpiforbi.bsky.social Munich Brain Day. #neuroskyence - will you be at either of these events? Let's connect!
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Campden Instruments @campdeninstruments.bsky.social · 30/04/2025
For all of those attending #BNA2025, in the poster zone 4, poster number PW 287, a poster entitled 'User interface refinements and quality assurance assessment in an updated popular tissue vibratome' is being presented. This presentation marks the launch of the 9000smz vibrating microtome! 🧠
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Campden Instruments @campdeninstruments.bsky.social · 28/04/2025
Good morning Liverpool! We are set up and ready for you #BNA2025! After a fantastic welcome reception, we can't wait to see all that @britishneuro.bsky.social has in store! If you're here, stop by booth #18. You might see something brand new in addition to our full range of 🧠products! Woo!
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Campden Instruments @campdeninstruments.bsky.social · 25/04/2025
Checkout a really exciting paper using our Bussey-Saksida Touchscreen Chambers! These results give a lot of food for thought and challenge many previous assumptions. Notably, the impact of daily administration of drugs should be considered in all cognitive testing! 🧠
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Campden Instruments @campdeninstruments.bsky.social · 25/04/2025
As we prepare a big announcement, we think it is a great time to peek into the past. Have you ever wondered how Campden Instruments got its name? The company was originally founded back in 1970 on Campden Hill Road, in the Kensington area of London, so the name initially helped people locate us!
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Campden Instruments @campdeninstruments.bsky.social · 22/04/2025
#BNA2025 is almost here! We will be attending the @britishneuro.bsky.social Festival of Neuroscience in Liverpool! We will be releasing VERY exciting news, so make sure you check out stand #18, and keep an eye out for Campden and @campdenird.bsky.social in other places! 🤓 Stay tuned for more! 🙊
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Campden Instruments @campdeninstruments.bsky.social · 17/04/2025
Will you be attending #APS2025 next week? If you are, make sure to stop by booth 914 and meet the @aurorascientific.bsky.social! They would also be happy to answer any questions you may have about Campden vibratomes!
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Campden Instruments @campdeninstruments.bsky.social · 17/04/2025
Turning up the cheesiness to wish all of those that are celebrating a Happy Easter Break! Whether this long weekend you are searching for eggs or important data, we wish you a very EGG-citing time filled with springful fun and a much-needed break! 🐰
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Reposted by Campden Instruments
RainbowLabCVS-UoL @rainbowlabuol.bsky.social · 14/04/2025
We’ve had a few requests to extend the deadline for applications for the CPW 2025 workshop @cpw-liverpool.bsky.social due to the Easter break. The deadline is now midday on 28th April! Application form is available from the webpage @livuni-ilcams.bsky.social www.liverpool.ac.uk/life-course-...
liverpool.ac.uk
Cell Physiology Workshop | Institute of Life Course and Medical Sciences | University of Liverpool linkedinblueskyThe Original RedbrickUniversity of Liverpool on FacebookLivUni on InstagramLivUn...
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Campden Instruments @campdeninstruments.bsky.social · 14/04/2025
Last week, we asked you to guess, based on a series of microscopy images, what samples were successfully sliced using our 7000smz-2 vibratome. The answer? Plant roots (more specifically eucalypt root) — to investigate fungal colonisation. Did you guess correctly? 🌱
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