under stressful conditions, E. coli may initiate its SOS response to downregulate cell division while continuing to make copies of its genome, resulting in filamentous, multinucleoid cells like this one. if conditions improve, the cell can then divide at multiple sites to yield multiple progeny. 🤓🔬
![Naoji Uezono, a member of Unit 731, described in a 1980s interview a grisly scene where Yoshimura had "two naked men put in an area 40-50 degrees below zero and researchers filmed the whole process until [the subjects] died. [The subjects] suffered such agony they were digging their nails into each other's flesh." Yoshimura's lack of remorse was evident in an article he wrote for the Japanese Journal of Physiology in 1950 in which he admitted to using 20 children and a three-day-old infant in experiments which exposed them to zero-degree-Celsius ice and salt water. Although this article drew criticism, Yoshimura denied any guilt when contacted by a reporter from the Mainichi Shimbun.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cfehfalmqxdmymznmomj2j6n/bafkreidguu46o6r6g3epigdnjo2cuvp3hhnib3koeu75hmtyxxpslur7ba)
