iiinova — where your digital self keeps evolving

Reposted by Caleb Browne

Matt Hill @cannabrain.bsky.social · 24/05/2025

And that’s a wrap folks for #CAN2025. Thanks to everyone who came and participated in the science and conversations and we conclude with the past (me), now present ( @rcbagot.bsky.social ) and future ( @markcembrowski.bsky.social ) chairs of the @canacn.bsky.social meeting. See you in Montreal 2026!

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Caleb Browne @calebbrowne.bsky.social · 13/04/2025

We hope these data will be a useful resource for the field, and that our findings could help guide the development of therapeutic strategies shaped by the unique impacts of different forms of substance use disorder.

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Caleb Browne @calebbrowne.bsky.social · 13/04/2025

Throughout the paper, outline general patterns of transcriptional regulation, gene networks and biological processes and affected, and try to identify some underlying regulatory systems involved.

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Caleb Browne @calebbrowne.bsky.social · 13/04/2025

Using RNAseq on FACS-sorted nuclei from D1 or D2 MSNs across different exposure conditions, we find that while these different classes of drugs induce a lot of parallel changes to the transcriptome, many patterns of gene expression are highly divergent, particularly in D2s.

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Caleb Browne @calebbrowne.bsky.social · 13/04/2025

Happy to share our new paper in Molecular Psychiatry, co-led by Philipp Mews with @ericjnestler.bsky.social, where we compare how cocaine and morphine cause cell-type-specific transcriptional restructuring in the nucleus accumbens to inform processes occurring in SUD. www.nature.com/articles/s41...

nature.com

Cocaine and morphine induce shared and divergent transcriptional regulation in nucleus accumbens D1 and D2 medium spiny neurons - Molecular Psychiatry

Molecular Psychiatry - Cocaine and morphine induce shared and divergent transcriptional regulation in nucleus accumbens D1 and D2 medium spiny neurons

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Caleb Browne @calebbrowne.bsky.social · 21/02/2025

🇨🇦🇨🇦🇨🇦💪💪💪

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Reposted by Caleb Browne

Scott Russo @scottrussophd.bsky.social · 12/02/2025

1/4 I am very pleased to share this new manuscript, “A crucial role for the cortical amygdala in shaping social encounters”, led by 2 spectacular postdocs, Dr. Tony Aubry who is on the job market, and coauthor @neuromanonyc.bsky.social Read it here: www.nature.com/articles/s41...

nature.com

A crucial role for the cortical amygdala in shaping social encounters - Nature

The posterolateral cortical amygdala and other connected brain regions have a key role in mediating the transition from investigative to aggressive behaviour in male mice.

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Reposted by Caleb Browne

Paul Frankland @franklandlab.bsky.social · 02/02/2025

Re-upping this: Deadline is Feb 15th. PI position at our Research Institute at The Hospital for Sick Children in Toronto. Successful candidate will be cross-appointed at U of T. Great research community, great city! Early- and mid-career applications welcome. can-acn.org/scientist-se...

can-acn.org

Scientist/Senior Scientist – Research Institute, Hospital for Sick Children, University of Toronto – Canadian Association for Neuroscience

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Reposted by Caleb Browne

Ciaran Murphy-Royal @murphyroyallab.org · 17/01/2025

Come join us @umontreal.ca - We're looking to recruit a Professor in the field of neurobiology, with a focus on linking neurodevelopment to neural circuit function and dysfunction. #neuroskyence #neuroscience 🧪 See ad below - www.fens.org/careers/job-...

fens.org

Principal Investigator in neurodevelopment/Assistant Professor - CHU Sainte-Justine Azrieli Research Centre/ Université de Montréal - Federation of European Neuroscience Societies

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Reposted by Caleb Browne

Karla Kaun @karlakaun.bsky.social · 21/01/2025

Omar Abubaker, Eric Nestler and I spoke about how science brings hope for those suffering from alcohol and substance use disorders at an Advocacy forum @sfn.org #SfN24. Our message is that as scientists we need to be better at communicating this. @ericjnestler.bsky.social

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