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Jon Boyle

@boylelab.bsky.social
995 followers 1.2K following 119 posts

Professor of Biology at University of Pittsburgh. Toxoplasma evolution placenta interactions virulence development. tragically a pirates fan can’t help it

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Jon Boyle @boylelab.bsky.social · 25/06/2026
“Only Brain”. Fantastic!
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Jon Boyle @boylelab.bsky.social · 25/06/2026
Mahahahah. I’m not happy tho. Just laughing morbidly at the stupidity
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Jon Boyle @boylelab.bsky.social · 24/06/2026
Some quality placenta drawings for you. So many different structures out there and so many different ways they are drawn. All are my favorite. #placenta #drawing
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Jon Boyle @boylelab.bsky.social · 22/06/2026
Look at this one!! A gem. Clear with art deco cows #neosporacaninum #verticaltransmission #parasitelifecycledrawings
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Jon Boyle @boylelab.bsky.social · 22/06/2026
It’s fantastic. I think we should all start hiring by hand illustrators again or at least draw things ourselves even if we are terrible.
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Jon Boyle @boylelab.bsky.social · 22/06/2026
More of this please!!!
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Jon Boyle @boylelab.bsky.social · 22/06/2026
Also this
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Jon Boyle @boylelab.bsky.social · 22/06/2026
This cat looks so menacing
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Jon Boyle @boylelab.bsky.social · 22/06/2026
Love this one
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Jon Boyle @boylelab.bsky.social · 22/06/2026
Yes I am old man yells at cloud.
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Jon Boyle @boylelab.bsky.social · 22/06/2026
Check this out
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Jon Boyle @boylelab.bsky.social · 22/06/2026
Longing for pre AI and pre Biorender schematics in scientific papers? Me too.
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Ward Q. Normal (he/him) @wardqnormal.bsky.social · 24/05/2026
It’s like Iran On your wedding day
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Jon Boyle @boylelab.bsky.social · 22/04/2026
Hope this data is useful for extending in vitro cultivation of Toxoplasma to more life stages and as a benchmark for determining how similar different life stages are to merozoites and male and female gametes. Thanks again to Hisham for being willing to take on this bold project for his PhD.
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Jon Boyle @boylelab.bsky.social · 22/04/2026
Lots of ways to get at this data yourself. The easiest is to download the cloupe file available on zenodo.19358900
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Jon Boyle @boylelab.bsky.social · 22/04/2026
AP2X6 knockout parasites cannot make oocysts and we think this is because AP2X6 helps to repress expression of merozoite genes to promote female gamete development.
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Jon Boyle @boylelab.bsky.social · 22/04/2026
Hisham used single cell rnaseq on pre sexual and sexual stages to examine their developmental trajectories. He identified multiple stage specific genes and identified at least one that is required for oocyst production, AP2X6.
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Jon Boyle @boylelab.bsky.social · 22/04/2026
Our work just came out today in print form in Nat Micro. Really a tour de force from Hisham Alrubaye on sexual development in Toxoplasma gondii. Well done! rdcu.be/feOj6
rdcu.be
A single-cell atlas of Toxoplasma sexual development in the feline intestinal tract
Nature Microbiology - Single-cell RNA sequencing is used to study the sexual development of Toxoplasma gondii in cats, generating a transcriptional atlas and showing that the female-specific gene...
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Viktor Winetrout @viktorwinetrout.bsky.social · 05/02/2026
This meeting could’ve been a karate match
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Kaitlyn Hajdarovic, Ph.D @khajdarovic.bsky.social · 25/01/2026
Fighting through snow so I can do my science. Animal care staff, building staff, clinical staff, nurses, doctors, veterinarians all work through these weather conditions to make the NIH run.
A snowy bus stop outside the NIH. Snow on the ground and sleeting down, everything is grey and white.
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Jon Boyle @boylelab.bsky.social · 20/01/2026
Yeah this is some serious grift. Gettin paid to kisss the ring.
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Shakira Kurosawa @jamtoday.bsky.social · 01/01/2026
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Jon Boyle @boylelab.bsky.social · 05/11/2025
Today I submitted a grant and I’m also getting a tooth pulled today which do yall think will be worse
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Jon Boyle @boylelab.bsky.social · 08/10/2025
I like these cause zoomed out they trigger a bit o trypophobia but zoomed in they don’t.
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Jon Boyle @boylelab.bsky.social · 08/10/2025
This is the fucking best. Rip city forever indeed
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Jon Boyle @boylelab.bsky.social · 07/10/2025
Hello lab my old friend.
Sucrose being stirred in a beaker
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Jon Boyle @boylelab.bsky.social · 14/06/2025
You are obligated to do so
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Jon Boyle @boylelab.bsky.social · 30/05/2025
Agree 100%
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Liz Ahern 🌈🇲🇽🏳️‍⚧️☮️ @austinmermaid.bsky.social · 29/05/2025
“I’m a transgender service member and today was my last day in uniform. After 11 years, eight months and 1 day I’m taking the uniform off for good. I will always be yours bc this rank, these skills, this name will always be me.” ~Technical Sargent Altesse Aurum #TransInMilitary 🫡 🏳️‍⚧️ @altessaurum
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Kate Starbird @katestarbird.bsky.social · 29/05/2025
Today, we received notice that our team’s last remaining NSF grant was terminated. For the first time since 2009, when I received an NSF Fellowship for Graduate Research, I have no active NSF grants.
The U.S. National Science Foundation (NSF) has undertaken a review of its award portfolio. Each award was carefully and individually reviewed, and the agency has determined that termination of certain awards is necessary because they are not in alignment with current NSF priorities.
Effective immediately, the following are terminated:
NSF AWARD ID:
2120496
NSF is issuing this termination to protect the interests of the government pursuant to NSF Grant General Conditions (GC-1) term and condition entitled 'Termination and Enforcement,' on the basis that they no longer effectuate the program goals or agency priorities. This is the final agency decision and not subject to appeal.
Costs incurred as a result of this termination may be reimbursed, provided such costs would otherwise be allowable under the terms of the award and the governing cost principles. In accordance with your award terms and conditions, you have 30 days from the termination date to furnish an itemized accounting of allowable costs incurred prior to the termination date.
Sincerely,
Jamie H. French, Division Director
Office of Budget Finance and Award Management (BFA) Division of Grants and Agreements (DGA)
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Vaughn Cooper @vscooper.micropopbio.org · 29/05/2025
Heartbreaking effects of NSF, Americorps cuts to Pittsburgh’s after school programs that support and enrich our city’s kids. The need and benefits of these programs is obvious. Isn’t this what we pay taxes for? Doubt philanthropy can take over. www.publicsource.org/federal-fund...
publicsource.org
Pittsburgh after-school programs left scrambling as federal funding cuts hit the region
Pittsburgh-area programs reel with recent federal grant terminations from the National Science Foundation.
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Jon Boyle @boylelab.bsky.social · 25/05/2025
This, more than anything else they are doing with funding levels etc, will ruin US Science and innovation.
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Greg Pak @gregpak.net · 22/05/2025
Just called Gillibrand and Schumer to demand they not only vote against the murderous Republican budget bill, but that they deny unanimous consent at every opportunity and do everything else they can to gum up the works. This is intolerable. Find your senators here and make your own calls: reps.fyi
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Brittany Charlton @britshmit.bsky.social · 22/05/2025
⚖️Heartbroken but proud to stand with fellow researchers in court today⚖️ NIH’s sudden grant cuts: 🚫 Silence lifesaving health equity work ⏳ Undermine years of progress ⚠️ Put vital discoveries at risk We won’t stop fighting for science & justice 🧪 👇More details from our @aclu.org representation👇
aclu.org
‘Devastated’ and ‘Hopeless.’ Researchers Speak Out on Funding Cuts | ACLU
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Jon Boyle @boylelab.bsky.social · 18/05/2025
Text recognition in photo on your phone !!
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Jon Boyle @boylelab.bsky.social · 15/05/2025
Instead of “Here put this in your baby. AI told us it will be fine”
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Jon Boyle @boylelab.bsky.social · 15/05/2025
Amazing super cool and IMPOSSIBLE without a) NIH funding and b) ANIMAL RESEARCH
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Jon Boyle @boylelab.bsky.social · 14/05/2025
Ok so I agree re: HIM but sadly what he’s saying here is “do your own research and be skeptical of experts”.
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Celeste Labedz @celestelabedz.bsky.social · 14/05/2025
The canceled grants aren't a perfect 1:1 with DEI-related projects, but what a reminder of who is and isn't doing the work to make science more equitable.
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Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 13/05/2025
"Women are PIs on 58% of the canceled grants, although they are PIs on only 34% of all active NSF grants. Similarly, Blacks are PIs on 17% of the terminated grants, although they make only 4% of the total pool. Hispanic PIs and those with disabilities were twice as likely to lose a grant."
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Trevon Logan @trevondlogan.bsky.social · 14/05/2025
The intense racial and gender segregation of science funding will be even more pronounced going forward. This was always the intent.
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darth™️ @darthbluesky.bsky.social · 08/05/2025
they put french fries in sandwiches rich that is what the heck is going on in pittsburgh i am all for it tbh
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Vaughn Cooper @vscooper.micropopbio.org · 07/05/2025
EvolvingSTEM in action at Pittsburgh Perry HS @evolvingstem.bsky.social www.wtae.com/article/pitt...
wtae.com
Federal freezes threaten Pitt's STEM outreach in high schools
Scientists at the University of Pittsburgh have been teaching inside local high schools for ten years through the Evolving-STEM program, which now faces potential federal funding cuts.
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Jon Boyle @boylelab.bsky.social · 01/05/2025
I grew up like that too. They gave music and media and the outside world so much power. Like it could take you even if you didn’t want it to.
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Dr. Casey Fiesler @cfiesler.bsky.social · 19/04/2025
I had an NSF grant on AI education canceled yesterday. I wasn’t given any kind of reason but I have a theory and it’s just as stupid as you might think. (I will probably have more to say on this once I have more details but for right now just: 😡 )
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Noam Ross @noamross.net · 14/04/2025
Just one example: In the past 2 weeks, NIH has terminated dozens of programs to support students pursuing scientific careers. These MARC or U-RISE (T34) grants provide rising undergraduates with opportunities and stipends to participate in science. Where are these programs? Not in the Ivy league:
A map showing colleges where T34 undergradaute training programs have been terminated by the NIH. Shown are: Spelman College
University Of Texas El Paso
University Of Alaska Anchorage
Texas State University
San Jose State University
Queens College
Nova Southeastern University
Nova Southeastern University
Nova Southeastern University
Marquette University
Kennesaw State University
Clark Atlanta University
City College Of New York
California Poly State U San Luis Obispo
Brooklyn College
University Of West Florida
University Of North Carolina At Pembroke
Rutgers The State Univ Of Nj Camden
University Of Nevada Reno
San Diego State University

Plus 30+ more unlabeled ones that are unconfirmed.
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Jon Boyle @boylelab.bsky.social · 11/04/2025
Ai to predict how a specific monoclonal antibody will distribute throughout the body 👍
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Jon Boyle @boylelab.bsky.social · 11/04/2025
Here’s how they’ll do it: 1. Say a lot of people are faking it 2. Vaccines 3. Food
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Jon Boyle @boylelab.bsky.social · 02/04/2025
I am so sorry. This is just so sad for you and so many others. 💔
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Chrystal Starbird @drstarbird.bsky.social · 02/04/2025
Finally got the notice. Very sad day for the MOSAIC program that supported some of the most amazing scientists I know, as well as some of the awesome people on my lab.
Letter from the NIH indicating that my grant has been terminated (though it seems we can keep the remaining funds for this year?)
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