This prospective multicenter study including individuals with hematuria evaluates the performance of a urinary DNA methylation test in identifying patients with high-grade or invasive bladder cancer.

On March 28, 2025, the Food and Drug Administration approved durvalumab. Read more.

Zachary Klaassen and Joshua Meeks discuss the need to move beyond single-arm trials in BCG-unresponsive bladder cancer treatment, given the current availability of multiple FDA-approved options. Dr. M...

Andrea Necchi: Neoadjuvant Chemotherapy VI-RADS Scores for Assessing Bladder Cancer Response to Neoadjuvant Immunotherapy with Multiparametric MRI / Andrea

Abstract. Extrachromosomal DNA (ecDNA) presents a promising target for cancer therapy; however, its spatial-temporal diversity and influence on tumor evolution and the immune microenvironment remain l...

Gianluca Giannarini: Rapid-fire debates bladder cancer at EAU 2025 / bladder cancer, cancer, EAU 2025, Gianluca Giannarini, OncoDaily, Oncology, Shilpa Gupta

Sabine D. Brookman-May: Pros for BCG outlined by Gianluca Giannarini at EAU2025 / cancer, EAU2025, Gianluca Giannarini, Laura S. Mertens, OncoDaily, Oncology,

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PURPOSETransurethral resection of bladder tumor (TURBT) is the initial staging procedure for new bladder cancers (BCs). For muscle-invasive bladder cancers (MIBCs), TURBT may delay definitive treatmen...

Bladder cancer treatment suffers from low therapeutic efficacy. Here the authors present radioactive 131I-labelled urease-powered nanobots that exhibit enhanced accumulation at the tumour site, enabli...

In some instances (<5%), non-muscle-invasive bladder cancer can progress to metastatic disease without any signs of bladder muscle or lympho-vascular invasion, a condition known as metastatic non-m...

IntroductionBladder cancer is one of the most important diseases that threatens oral and dental health due to its nature and side effects of chemotherapy. Th...

Researchers are a step closer to revolutionising how doctors use radiotherapy to treat patients with muscle-invasive bladder cancer.

YouTube video by European Association of Urology

Neoadjuvant chemotherapy followed by radical cystectomy is the standard treatment for cisplatin-eligible patients with muscle-invasive bladder cancer. Adding perioperative immunotherapy may improve...

PURPOSEThis study aimed to assess long-term follow-up after chemoresection with mitomycin (MMC), a nonsurgical treatment modality for recurrent nonmuscle invasive bladder cancer (NMIBC). At the time o...

En bloc transurethral resection of the bladder (eTURB) might improve the surgical management of non–muscle-invasive bladder cancer (NMIBC) in comparis…

Whether extended lymphadenectomy is associated with improved disease-free and overall survival, as compared with standard lymphadenectomy, among patients with localized muscle-invasive bladder canc...