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Lecuit Lab

@biupasteur.bsky.social
353 followers 253 following 17 posts

Biology on Infection Unit at Institut Pasteur and Inserm

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Lecuit Lab @biupasteur.bsky.social · 03/10/2025
Please note this interesting symposium, organised by the Louis Jeantet Foundation in Geneva, which can also be followed remotely. #LouisJeantetSymposium
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Lecuit Lab @biupasteur.bsky.social · 19/09/2025
We are hiring a postdoc in bacterial genomics and evolution. research.pasteur.fr/wp-content/u...
research.pasteur.fr
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Reposted by Lecuit Lab
Institut Pasteur | 130 years of biomedical research @pasteur.fr · 07/07/2025
🏆 Congratulations to Simonetta Gribaldo @sgribaldo.bsky.social and Marc Lecuit @biupasteur.bsky.social ! Our two researchers have been awarded prestigious ANR Chairs of Excellence in Biology/Health for their innovative projects.
pasteur.fr
"Chairs of Excellence in Biology/Health": two new Institut Pasteur laureates
The Institut Pasteur is delighted that two of the winners of the new "Chairs of Excellence in Biology/Health" call for proposals round launched by the French National Research Agency (ANR) are its own...
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Reposted by Lecuit Lab
Nature Reviews Microbiology @natrevmicro.nature.com · 07/05/2025
New online! Chikungunya virus and other emerging arthritogenic alphaviruses
nature.com
Chikungunya virus and other emerging arthritogenic alphaviruses
Nature Reviews Microbiology, Published online: 07 May 2025; doi:10.1038/s41579-025-01177-8In this Review, Weaver and colleagues discuss the transmission cycles of arthritogenic alphaviruses, their vectors, epidemiology, transmission dynamics, evolution, pathophysiology and immune responses. They also outline strategies and countermeasures to anticipate and mitigate the impact of arthritogenic alphaviruses on human health.
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Reposted by Lecuit Lab
Thelonevirologist @thelonevirologist.bsky.social · 07/05/2025
Chikungunya virus and other emerging arthritogenic alphaviruses www.nature.com/articles/s41...
nature.com
Chikungunya virus and other emerging arthritogenic alphaviruses - Nature Reviews Microbiology
In this Review, Weaver and colleagues discuss the transmission cycles of arthritogenic alphaviruses, their vectors, epidemiology, transmission dynamics, evolution, pathophysiology and immune responses...
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Lecuit Lab @biupasteur.bsky.social · 28/02/2025
We are hiring! Interested in infection biology, immunology, microbiology? Funded postdoctoral position in our lab at Institut Pasteur research.pasteur.fr/en/team/biol... @inserm.fr Contact us at postdoc.biu@pasteur.fr research.pasteur.fr/en/job/funde...
research.pasteur.fr
Funded postdoctoral position in the Lecuit lab at Institut Pasteur - Research
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Reposted by Lecuit Lab
Louis-Jeantet Foundation @louisjeantetfdn.bsky.social · 12/12/2024
📢NOMINATIONS for the 2026 #LouisJeantetPrize and #CollenJeantetPrize are open. Support great #EuropeanResearch and submit your nomination by February 21, 2025. 🙏Please share! jeantet.ch/en/nominatio...
jeantet.ch
Nominations | Fondation Louis-Jeantet |
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Lecuit Lab @biupasteur.bsky.social · 23/11/2024
6/6 Thanks to everybody involved, including Enzo Gadin, Arthur Frouin, Olivier Disson, Lei Huang, Charlotte Gaultier, Afonso Vieira, @clairemaudet.bsky.social, @epcrocha.bsky.social, Hugues Aschard, @pasteur.fr, @inserm.bsky.social
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Lecuit Lab @biupasteur.bsky.social · 23/11/2024
1/6 Excited to share our new findings published today in @naturemicrobiol.bsky.social, explaining what drives virulence heterogeneity in Listeria monocytogenes! @lukashafner.bsky.social @biupasteur.bsky.social www.nature.com/articles/s41...
nature.com
Differential stress responsiveness determines intraspecies virulence heterogeneity and host adaptation in Listeria monocytogenes - Nature Microbiology
Differences in virulence across the Listeria monocytogenes species are determined by the fine-tuning of SigB pathway responsiveness and reflect host adaptation.
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Lecuit Lab @biupasteur.bsky.social · 23/11/2024
2/6 Previously, bacterial virulence was thought to reflect the content of core virulence genes as well as the presence of accessory virulence genes, which account for virulence heterogeneity. www.youtube.com/watch?v=liJm...
youtube.com
Differential stress responsiveness determines virulence heterogeneity in Listeria monocytogenes
YouTube video by Lukas Hafner
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Lecuit Lab @biupasteur.bsky.social · 22/11/2024
The Listeria National Reference Center and WHO Collaborating Center, and many more!
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Lecuit Lab @biupasteur.bsky.social · 22/11/2024
5/6 It also sheds light on the mechanism by which certain Listeria monocytogenes clonal complexes are more virulent, host associated, and clinically associated than others, as we also reported www.nature.com/articles/s41...
nature.com
Bacterial inhibition of Fas-mediated killing promotes neuroinvasion and persistence - Nature
Studies in a mouse model of neurolisteriosis show that the effector protein InlB produced by Listeria monocytogenes protects infected monocytes in the host from T cell-mediated cell death, and thereby...
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Lecuit Lab @biupasteur.bsky.social · 22/11/2024
4/6 This unique overarching mechanism, which is unexpected, explains the overall virulence heterogeneity of Listeria monocytogenes species - from isolates to lineages, as we had reported www.nature.com/articles/ng....
nature.com
Uncovering Listeria monocytogenes hypervirulence by harnessing its biodiversity - Nature Genetics
Marc Lecuit, Sylvain Brisse and colleagues combine Listeria monocytogenes population genomic data with human epidemiological and clinical data to study human listeriosis. They report new putative viru...
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Lecuit Lab @biupasteur.bsky.social · 22/11/2024
3/6 Here, we have identified a new mechanism that explains virulence heterogeneity, not by gene content but by the differential regulation of core virulence genes, driven by differential stress response.
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Lecuit Lab @biupasteur.bsky.social · 22/11/2024
👏👏👏Congratulations to Lukas & all co-authors
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