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BioPattern Lab

@biopatternlab.bsky.social
71 followers 106 following 4 posts

Research group based in the Department of Infectious Disease at Imperial College London | Interested in building microbiome models and synthetic tissues 🦠🖨️🔬| (Very) occasionally led by @ravinash.bsky.social bpl-imperial.github.io

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Reposted by BioPattern Lab
Alex McCarthy @alex-mccarthy.bsky.social · 22/06/2026
New paper 📄 out in @natcomms.nature.com: We show that bacteria can target inhibitory receptors expressed on neutrophils to actively subvert antibody-driven immune responses, using LILRB3 and Group B Streptococcus as a study system. Link: www.nature.com/articles/s41....
nature.com
Bacterial targeting of the neutrophil inhibitory receptor LILRB3 to evade antibody immunity - Nature Communications
Antibody-mediated immunity is essential to protect hosts from bacterial pathogens. Here, the authors show that Streptococcus agalactiae targets inhibitory LILRB3 receptor on neutrophils to supress ant...
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European Synthetic Cell Initiative @syncelleu.bsky.social · 24/04/2026
Last day of the #SynCell2026 conference. Today's programme: a poster session, keynote talks, a panel discussion on SynCell communities, and more. See the full programme: edu.nl/aakge Photos from yesterday's talks
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Harry Low’s Lab @lowlab.bsky.social · 20/04/2026
Most bacteria remain uncultured with vast microbial ‘dark matter’ awaiting discovery.. to address this am excited to share EDEN - an enhanced domestication method to grow uncultured bacteria & new diversity. Using EDEN we isolate a new species active against MDR pathogens.. doi.org/10.1093/isme...
doi.org
An enhanced domestication method for uncultured bacteria
Abstract. When environmental bacteria transition to laboratory conditions, a process termed domestication, the shift from the native habitat to a culture m
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Rachel M. Wheatley @rachelmwheatley.bsky.social · 30/03/2026
🔊 Looking for a Research Assistant in Bacterial Evolution to join my lab 🦠 🥼Main duties: Research (AMR + microbiome) + lab assistance. ⏲️ Post duration: 30 months 🗓️ Closing date for applications: 20th April 2026 💰 Salary: ~£35k Details and how to apply: tinyurl.com/2a3v66y7 Please share!
lnkd.in
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Claudia Contini @continiclau.bsky.social · 20/03/2026
🚨new #PhD #opportunity open in our group! In collaboration with John Tregoning,we are recruiting for a project focused on #engineering #synthetic #vesicle platforms for programmable #immune #training and #vaccine #delivery. 📅 Application deadline: 16th April www.imperial.ac.uk/medicine/stu...
imperial.ac.uk
How to apply | Faculty of Medicine | Imperial College London
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BioPattern Lab @biopatternlab.bsky.social · 19/03/2026
This is now open with a deadline of 13th of April!
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Sean Booth @s-booth.bsky.social · 10/03/2026
For my first bluesky post I'm stoked to share this work, done with fellow Foster lab alum Connor Sharp! (@magicmicrobe.bsky.social) We set out to discover why bacteria carry multiple similar weapons for attacking other bacteria. www.biorxiv.org/content/10.6...
A stylized cartoon of a bacterial cell. It is blue with three long wavy filaments curved around it. On the top left are four cyan spiral spikes, on the bottom left are four navy spiral spikes. Floating on the right of the cell are three groups of stylized proteins. Each group has three wrapped up helices, on group is pink, one purple, one magenta.
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BioPattern Lab @biopatternlab.bsky.social · 07/03/2026
🚨 Four fully funded PhD studentships 🚨 @imperialmed.bsky.social , @imperialcollegeldn.bsky.social We will be recruiting soon for four PhD positions to build a mini-cohort centered using synthetic cells for medical applications Check out projects here: www.imperial.ac.uk/medicine/stu...
imperial.ac.uk
Research cohorts
The EPSRC University Doctoral Landscape Award funded PhD projects in the Faculty of Medicine are listed below under each mini-cohort. PhD projects wi...
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Christos C. Ioannou @ccioannou.bsky.social · 18/02/2026
📢📢📢Lectureships at Bristol!📢📢📢 We're hiring 3 x lecturers (=assistant professor) in Biological Sciences, across the discipline. Great department, great colleagues, great building, great city Details here: www.bristol.ac.uk/jobs/find/de...
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Imperial Medicine @imperialmed.bsky.social · 08/02/2026
✨We’re looking for up to 20 new non-clinical Assistant Professors to join our world-class academic community.💫 Could that be you? Find out more and apply by 11 March 2026: www.imperial.ac.uk/jobs/search-...
Dr Vanessa Sancho-Shimizu (a UKRI Future Leaders Fellow and Reader in the sections of Paediatrics Infectious Diseases and Virology investigating the human genetic basis of life-threatening infections) in a lab environment. She is wearing safety glasses and a white lab coat.
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Imperial Medicine @imperialmed.bsky.social · 05/02/2026
"I want the Department to be a happy, supportive, diverse, and inclusive environment where we attract talented individuals, deliver world‑leading education, research, and innovation..." Get to know Prof Aubrey Cunnington, new Head of @imperialinfect.bsky.social www.imperial.ac.uk/news/article...
imperial.ac.uk
Introducing Professor Aubrey Cunnington, new Head of the Department of Infectious Disease
We had a conversation with the Head of Department on his vision, priorities, and hopes for the future.
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Engineering Biology Interdisciplinary Research Centre @engbioirc.bsky.social · 27/01/2026
🧬🧫 EngBio ECRs Meetup is back! 📅 Mon 16 Feb | ⏰ 12pm 📍 Postdoc Centre Mill Lane Two great talks on capsid proteins & RNA organelles in bacteria from Daniela Gjorgjevikj and Brian Ng 🎟️ Sign Up at www.tickettailor.com/events/engin... #EngBio #ECRs #RNA #bacteria #CapsidProteins
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 19/12/2025
I was at Ghent to talk about our project where we use a special printer to pattern artificial cells at Imperial College London @imperialcollegeldn.bsky.social. It's a collaboration between me, Jorin, Rav, and Alex. Cannot wait to share the results! @ravinash.bsky.social @biopatternlab.bsky.social
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Erik Bakkeren @erikbakkeren.bsky.social · 07/11/2025
Can we leverage bacterial competition for targeted replacement of harmful strains? Maybe! Our recent piece in @natmicrobiol.nature.com provides a theoretical framework and a set of experiments to show what it might take: www.nature.com/articles/s41...
nature.com
Strain displacement in microbiomes via ecological competition - Nature Microbiology
Mathematical modelling and experimental tests reveal principles that govern displacement of a resident strain by an invader in microbial communities.
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Connor Sharp @magicmicrobe.bsky.social · 05/11/2025
So happy to share this! Bacteriocins were first discovered over 100 years ago, but what do they actually do? We look at >1000 bacteriocin plasmids and find links to virulence and antimicrobial resistance, and frequent bacteriocin sharing in Enterobacteriaceae. www.nature.com/articles/s41...
nature.com
Bacterial warfare is associated with virulence and antimicrobial resistance - Nature Communications
Bacteria employ a range of competition systems that deliver toxins to inhibit competing strains. This study shows that these systems are particularly important for the ecology of virulent and antibiot...
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Harry Low’s Lab @lowlab.bsky.social · 29/10/2025
Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see www.imperial.ac.uk/jobs/search-...
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Oliver Meacock @olimeacock.bsky.social · 30/10/2025
I am excited to announce two PhD opportunities! Come and join our interdisciplinary team in Sheffield, UK. - Destroying forever chemicals with microbes and cold plasma: tinyurl.com/mth8ymx5 - Learning how motile bacteria make decisions: tinyurl.com/2hmc9a8u UK and overseas students welcome to apply!
tinyurl.com
ECOSOLUTIONS DFA - Harnessing microbes and cold plasma to concentrate and destroy ‘forever chemicals’ in food associated ecosystems at University of Sheffield on FindAPhD.com
PhD Project - ECOSOLUTIONS DFA - Harnessing microbes and cold plasma to concentrate and destroy ‘forever chemicals’ in food associated ecosystems at University of Sheffield, listed on Find...
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Department of Infectious Disease @imperialinfect.bsky.social · 21/10/2025
Join us for our next online seminar with Dr Francesco Boccellato from @ludwigcancer.bsky.social @ndm.ox.ac.uk. He will discuss epithelial barrier homeostasis and response to infections. 🗓️28 October, 1-2pm 📌South Kensington/Online 👉 www.imperial.ac.uk/events/19994...
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BioPattern Lab @biopatternlab.bsky.social · 10/10/2025
In the spirit of new things at the start of the @imperialcollegeldn.bsky.social year, we took a new group photo! 🚨Exciting news🚨: three postdoctoral researchers were awarded external fellowships: Cameron Boggon (SNF), Inez Roegiers (HFSP), Witold Postek (MSCA). @imperialinfect.bsky.social
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Reposted by BioPattern Lab
Michael Booth @drmikebooth.bsky.social · 05/08/2025
We have dramatically increased splice switching *and* RNase-H ASO activity by conjugating a nuclear importer! Published in JACS (@jacs.acspublications.org ‬) Led by Disha Kashyap, with Tom Milne+@natahub.org ‬ @uclchemistry.bsky.social 🧬🧪 #chemsky pubs.acs.org/doi/10.1021/...
Nuclear import increases ASO activity by by RNase H and splice switching mechanisms
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Tami Lieberman @contaminatedsci.bsky.social · 22/07/2025
We are on the lookout for postdocs for two different projects at the intersection of ecology, evolution, and the human microbiome. See thread for more information and reach out!
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David Riglar @driglar.bsky.social · 20/07/2025
Excited to share the latest paper from the Riglar lab @imperialinfect.bsky.social & @crick.ac.uk. We use #synbio for biosensor discovery in our quest to build 'smart probiotics' to sense and treat disease. Well done @clare-r.bsky.social et al! Thanks to @wellcometrust.bsky.social for funding!
embopress.org
A discovery platform for identification of host-induced bacterial biosensors from diverse sources | Molecular Systems Biology
imageimageA screen for inducible biosensing components to drive a bacterial synthetic memory circuit is designed using barcoded libraries of sensory systems. Testing and validation in conventional mic...
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Reposted by BioPattern Lab
Harry Low’s Lab @lowlab.bsky.social · 28/07/2025
Please RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏 www.imperial.ac.uk/media/imperi...
imperial.ac.uk
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BioPattern Lab @biopatternlab.bsky.social · 15/05/2025
Great to see our CIE Mentoring Programme @imperialcollegeldn.bsky.social growing every year 🙌 ! We'll be funding lab placements over the summer thanks to EPSRC. www.imperial.ac.uk/news/264013/...
imperial.ac.uk
Mentoring programme supports record number of young scientists | Imperial News | Imperial College London
The CIE (Confronting Inequality in Education) Mentoring Programme has completed its most successful year yet, supporting 69 Year 12 students.
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