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Biomedical Journal

@biomedj.bsky.social
366 followers 282 following 174 posts

Publishing in all fields of clinical & biomedical sciences. Open access. Impact Factor = 6.3

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Biomedical Journal @biomedj.bsky.social · 04/10/2026
Clinical Landscape of #Microbiome Modulators in Gynecological Tumor Treatment: From Pre-Clinical to Clinical Trials www.sciencedirect.com/science/arti... #OpenAccess #MicroSky #MedSky
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Biomedical Journal @biomedj.bsky.social · 04/10/2026
Harnessing Acoustic Energy Against Orthopedic Biofilms: Ultrasound-Based Therapeutic Strategies for Implant-Associated and Bone Infections www.sciencedirect.com/science/arti... #OpenAccess #biofilms
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Biomedical Journal @biomedj.bsky.social · 30/09/2026
Zfp469 Deletion Attenuates Liver Fibrosis by Suppressing Extracellular Matrix Production in Hepatic Stellate Cells www.sciencedirect.com/science/arti... #OpenAccess #Liver #MedSky
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Biomedical Journal @biomedj.bsky.social · 26/09/2026
Backs under pressure: measuring and estimating lumbar spinal loads. Biomedical Journal issue on lumbar load assessment, cancer signaling, multi‑omics metabolism, oral SCC, HBsAg predictors, asthma, antivirals, tear function. www.sciencedirect.com/science/arti... #OpenAccess #MedSky
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Biomedical Journal @biomedj.bsky.social · 22/09/2026
The Mononuclear Phagocyte System: A Dispersed Organ. Mononuclear phagocytes show broad organ roles and plasticity. This issue reviews their systemic functions beyond #immunity www.sciencedirect.com/science/arti... #OpenAccess #immunology #ImmunoSky #MedSky
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Delthia Ricks @dricks.bsky.social · 21/09/2026
Pennsylvania's measles epidemic is being met with both defiance and a rush to vaccinate. As the epidemic grows to more than 700 confirmed cases, the largest in the country, some people remain opposed to vaccines & others are rushing to get the shots www.nytimes.com/2026/09/20/u...
nytimes.com
Pennsylvania Measles Outbreak Leads to an Increase in Vaccinations (Gift Article)
As the outbreak grows to more than 700 confirmed cases, the largest in the country, some people remain opposed to vaccines and others are rushing to get the shots.
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Biomedical Journal @biomedj.bsky.social · 19/09/2026
Dose-dependent arginine availability is associated with metabolic remodeling and immune phenotypes during development www.sciencedirect.com/science/arti... #OpenAccess #metabolism #immunity #immunology #MedSky #ImmunoSky
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Katherine Stiles @katherinestiles.org · 19/09/2026
Stanford Medicine research reveals that the brain is two distinct organs that have evolved independently over millions of years. The findings were published in Nature Neuroscience on 18 September 2026.
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Biomedical Journal @biomedj.bsky.social · 17/09/2026
The Incretin Revolution: Integrating Incretin-Based Therapies into Clinical Care. #Incretin therapies reshape care, improving multiple obesity‑linked diseases and offering a practical framework for broader clinical use. www.sciencedirect.com/science/arti... #OpenAccess #GLP1 #obesity #MedSky
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Biomedical Journal @biomedj.bsky.social · 12/09/2026
Structural Overview of GLP-1 Analogs. GLP‑1 analogs use structural tweaks to boost stability, receptor affinity, half‑life, and signaling, enabling next‑gen incretin drugs. www.sciencedirect.com/science/arti... #OpenAccess #obesity #diabetres #GLP1
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Biomedical Journal @biomedj.bsky.social · 04/09/2026
KRAS Expression Complements Genomic Profiling in Identifying Therapeutic Vulnerability in #GastricCancer www.sciencedirect.com/science/arti... #OpenAccess #cancer #biomarker #MedSky
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Biomedical Journal @biomedj.bsky.social · 26/08/2026
Age-stratified gut #microbiome variation in a Taiwanese cohort. Gut microbiome shifts with age. Some genera consistently age‑linked. Adult profiles only modestly predict age. www.sciencedirect.com/science/arti... #OpenAccess #aging #microbiota #MicroSky #MedSky
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Biomedical Journal @biomedj.bsky.social · 26/08/2026
Age-stratified gut #microbiome variation in a Taiwanese cohort. Gut microbiome shifts with age. Some genera consistently age‑linked. Adult profiles only modestly predict age. www.sciencedirect.com/science/arti... #OpenAccess #aging #microbiota #MicroSky #MedSky
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Biomedical Journal @biomedj.bsky.social · 14/08/2026
Longitudinal Changes in Clonal Distribution and Fluoroquinolone Resistance of Ocular MRSA. Taiwan ocular #MRSA shifted from CC59 to drug-resistant CC8, reducing fluoroquinolone efficacy and urging surveillance. www.sciencedirect.com/science/arti... #OpenAccess #MicroSky #MedSky
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Biomedical Journal @biomedj.bsky.social · 09/05/2026
The clockwork macrophage: Timing in #innateimmunity (free review article) www.sciencedirect.com/science/arti... #OpenAccess #circadian #immunity #ImmunoSky #MedSky
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Biomedical Journal @biomedj.bsky.social · 06/08/2026
Gastric #microbiota composition and its association with rescue eradication outcomes in refractory #Helicobacter pylori infection www.sciencedirect.com/science/arti... #OpenAccess #MicroSky #MedSky
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Biomedical Journal @biomedj.bsky.social · 04/08/2026
Low-energy extracorporeal shock wave therapy is associated with reduced #inflammation and #fibrosis in an E2-induced rat model of #endometriosis and remains effective under #menopause -mimicking conditions www.sciencedirect.com/science/arti... #OpenAccess #MedSky
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Katherine Stiles @katherinestiles.org · 04/08/2026
Could eating less protein slow ageing?
newscientist.com
Could eating less protein slow ageing? | New Scientist
Protein is everywhere, but studies – mostly in non-human animals – suggest that limiting our intake could extend our lifespan
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Biomedical Journal @biomedj.bsky.social · 03/08/2026
Distinguishing true from false idiopathic pulmonary #fibrosis : Progress in biomarkers for early identification of #rheumatoidarthritis www.sciencedirect.com/science/arti... #OpenAccess #arthritis #lungs #MedSky
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Dr. Aaron Thierry @thierryaaron.bsky.social · 03/08/2026
A first year above 2C in the mid-2030s now looks plausible. 0.5C was first passed in 1980, 1.0C in 2010 and 1.5C in 2024. The 15-year trend runs at 0.42C per decade. The 2026 and 2027 points for the current El Nino are estimates. We're not remotely ready!
Line chart titled "A first year above 2 C in the mid-2030s looks increasingly plausible". It shows global mean surface temperature from 1940 to 2050 as the annual anomaly against the 1850 to 1900 baseline, in degrees C. Data is ERA5 from Copernicus, running to 31 July 2026.

A thin gold line shows individual years, wobbling around a thick dark blue smoothed trend. Both sit near 0.2 C through the 1940s to the early 1970s, then climb steadily from the mid-1970s onward.

Three red dots mark the first year each threshold was passed. 0.5 C in 1980, 1.0 C in 2010 and 1.5 C in 2024. Labels beneath note the gap of 30 years between the first two and 14 years between the second and third. Everything above 1.5 C is shaded pink.

Two dashed lines run forward from 2025. A blue line follows the 15-year trend of 0.42 C per decade and reaches 2 C in 2037. A fainter grey line follows the 30-year trend of 0.27 C per decade and reaches 2 C in 2044.

Two orange circles mark estimates for the developing El Niño, at about 1.5 C for 2026 and about 1.7 C for 2027.
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Biomedical Journal @biomedj.bsky.social · 01/08/2026
Imipramine Reverses Sorafenib Resistance in Hepatocellular Carcinoma by Targeting the BLOC1S5/FOXO1 Signaling Axis www.sciencedirect.com/science/arti... #OpenAccess #cancer #liver #MedSky
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Biomedical Journal @biomedj.bsky.social · 15/07/2026
Corticosteroid Stewardship - From Awareness to Action Letter to the editor: Corticosteroid bursts pose serious risks. Evidence shows many uses lack benefit & stewardship programs can sharply cut unsafe prescribing www.sciencedirect.com/science/arti... #openAccess #MedSky
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Biomedical Journal @biomedj.bsky.social · 12/07/2026
Targeting long non-coding RNA H19 attenuates PKM2 deficiency-driven stemness property in tongue #cancer www.sciencedirect.com/science/arti... #OpenAccess #MedSky
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Biomedical Journal @biomedj.bsky.social · 12/07/2026
Association of HBsAg levels and HBV relapse patterns with HBsAg seroclearance following entecavir or tenofovir cessation www.sciencedirect.com/science/arti... #OpenAccess #hepatitis #MedSky
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Biomedical Journal @biomedj.bsky.social · 12/07/2026
Hydrogen-generating silicon-based agent is effective in a mouse model of ovalbumin-induced allergic bronchial #asthma www.sciencedirect.com/science/arti... #OpenAccess #MedSky
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Biomedical Journal @biomedj.bsky.social · 01/07/2026
Exploring the mechanism of #acupuncture for Chronic Atrophic #Gastritis based on bioinformatics and network topology strategies www.sciencedirect.com/science/arti... #OpenAccess #MedSky
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TRAstonDrs @castltrastondrs.medsky.network · 01/07/2026
#Medsky🧪 #neurosky #IDsky #publichealth Inflammatory memory in the central nervous system (CNS) is primarily driven by epigenetic reprogramming in long-lived innate immune cells, specifically microglia and astrocytes, @nature.com www.nature.com/articles/s41... www.nature.com/articles/s41...
nature.com
Epigenetic mechanisms of inflammatory memory in the central nervous system - Nature Immunology
Ye and Quintana discuss emerging evidence of inflammatory memory in the CNS and discuss its underlying mechanisms.
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Jeffrey Townsend @jeffreytownsend.bsky.social · 22/06/2026
Tumor driver co-mutation patterns are not conclusions—they are hypotheses. Mutual exclusivity/co-occurrence in cancer genomes become biologically meaningful (i.e. informative of epistasis) only when evaluated in the context of mutation-rate heterogeneity. 🧪: onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Empowering Inference of Epistasis on the Basis of Mutual Exclusivity, Co‐Occurrence, Functional Antagonism and Synergy in ERK‐Pathway Oncogenes
Click on the article title to read more.
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Biomedical Journal @biomedj.bsky.social · 19/06/2026
From Intradiscal Pressure to Multimodal Estimation of Lumbar Spinal Loads www.sciencedirect.com/science/arti... #OpenAccess #MedSky
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Biomedical Journal @biomedj.bsky.social · 16/06/2026
Coumarins as modulators of #autophagy and PI3K/mTOR signaling: Implications for next-generation #cancer therapies www.sciencedirect.com/science/arti... #OpenAccess #MedSky
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Delthia Ricks @dricks.bsky.social · 15/06/2026
Ebola cases in eastern Congo climb to 782 and deaths reach 181. However, the number of cases in the Congo is believed to be higher because the outbreak was confirmed May 15, weeks after it's suspected to have begun & the contact tracing coverage rate is at 56%, a sharp decline from last week👇
apnews.com
Ebola cases in eastern Congo climb to 782 and deaths reach 181, authorities say
The Congolese Ministry of Health reports that confirmed Ebola cases in Congo have increased to 782, with 181 deaths.
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TRAstonDrs @castltrastondrs.medsky.network · 16/06/2026
#Medsky🧪 #IDsky #oncosky #immunosky When cells experience genotoxic stress or severe nuclear envelope anomalies, #STING (Stimulator of Interferon Genes ) translocates into the nucleus, accumulates on chromatin, and directly binds to nascent DNA. by actively promoting replication stress,
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Biomedical Journal @biomedj.bsky.social · 14/06/2026
Impact of Genetic Variants in Cyclophosphamide-Metabolizing Enzymes on Clinical Outcomes After Haploidentical Hematopoietic Stem Cell Transplantation www.sciencedirect.com/science/arti... #OpenAccess #genetics #transplantation #MedSky
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TRAstonDrs @castltrastondrs.medsky.network · 14/06/2026
#Medsky🧪 #obsky #Vaccinesmatter #publichealth #COVID19vaccination during pregnancy has been extensively evaluated showing a dual benefit: protection of the mother and passive immunisation of the neonate during the early months of life. @jidjournal.bsky.social www.sciencedirect.com/science/arti...
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Biomedical Journal @biomedj.bsky.social · 10/06/2026
PRMT5-mediated methylation of LKB1 controls PD-L1 expression in NSCLC. PRMT5 modulates PD‑L1 via the LKB1–AMPK axis in NSCLC, shaping #immunotherapy response & offering a biomarker‑guided strategy. www.sciencedirect.com/science/arti... #OpenAccess #MedSky
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TRAstonDrs @castltrastondrs.medsky.network · 08/06/2026
#Medsky🧪 #publichealth Not all people can exercise.Exercise-induced anaphylaxis - a rarely heard of severe allergic reaction to moderate exercise & can cause intense itching all over the body .
theconversation.com
Yes, you really can be allergic to exercise – and the symptoms can be serious
Between 2.3% and 5% of all cases of anaphylaxis globally are triggered by exercise.
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The Journal of Infectious Diseases @jidjournal.bsky.social · 09/06/2026
What is the optimal RSV immunisation strategy for infants born in the RSV off-season? ✅ Just Accepted 🔗 bit.ly/4ofctjd
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Biomedical Journal @biomedj.bsky.social · 06/06/2026
Ultrasound-Guided Intervention in Adhesive Capsulitis: A Comprehensive Review of Therapeutic Strategies www.sciencedirect.com/science/arti... #OpenAccess #ultrasonography #corticosteroid #MedSky
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Ian M. Mackay, PhD (he/him) 🦠🤧🧬📑🦟🧀 @mackayim.bsky.social · 06/06/2026
The previous 22 days saw Australian #flu cases rise by an average of 148 cases per day. Over the past day, cases have risen by 244. How #Flu2026 goes from here, or how it ends, is for people who like to guess about things to say.
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Biomedical Journal @biomedj.bsky.social · 02/06/2026
Problematic #ChatGPT Use: Manifestations, Etiologies, and Evaluation www.sciencedirect.com/science/arti... #OpenAccess #AI #ArtificialIntelligence
sciencedirect.com
Problematic ChatGPT Use: Manifestations, Etiologies, and Evaluation
ChatGPT has rapidly permeated various domains, including education, industry, creativity, and daily life. While offering efficiency and emotional enga…
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Delthia Ricks @dricks.bsky.social · 01/06/2026
A novel pill doubles survival in pancreatic cancer, a disease that has been extraordinarily difficult to treat. Results from the RASolute 302 trial herald a new standard of care for patients who had failed previous therapy. Results reported at the American Society for Clinical Oncology
medpagetoday.com
'A Grand Slam' in Pancreatic Cancer: Novel Pill Doubles Survival
RASolute 302 findings herald a new standard of care in previously treated patients
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Katherine Stiles @katherinestiles.org · 02/06/2026
· #MedSky · Major surgery may accelerate memory loss in 1 in 7 older adults
medicalxpress.com
Major surgery may accelerate memory loss in 1 in 7 older adults
Going through surgery can take a significant toll on a patient's physical health and capabilities, especially if they are elderly. A recent study found that the effects extend far beyond mobility and ...
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Healthcare-Global @healthcare-global.bsky.social · 02/06/2026
www.news-medical.net/news/2026060...
news-medical.net
New brain probe simultaneously records and controls neuron activity
A new breakthrough technology, co-developed by UCL scientists, that simultaneously records and manipulates neuron activity deep within the brain could transform our understanding of neural circuits an...
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TRAstonDrs @castltrastondrs.medsky.network · 02/06/2026
#Medsky🧪 #pedsky #IDsky #neurosky #episky #publichealth Pediatric #autoimmunity is rapidly shifting from being viewed as isolated, single organ-specific entities to a unified framework of shared systemic immune vulnerability @lancetchildadol.bsky.social www.thelancet.com/journals/lan...
thelancet.com
Paediatric autoimmunity: from single entity to shared vulnerability
Autoimmunity arises from a breakdown of adaptive immune tolerance, whereby impaired recognition of self-antigens triggers inappropriate immune responses leading to tissue injury and organ dysfunction....
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Biomedical Journal @biomedj.bsky.social · 29/05/2026
Post-COVID-19 epidemiology of pneumococcal disease in Taiwan: escalating serotype replacement and antimicrobial resistance in all ages www.sciencedirect.com/science/arti... #OpenAccess #COVID #epidemiology #MicroSky #MedSky
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Biomedical Journal @biomedj.bsky.social · 29/05/2026
Displaced minds: ecologies of #depression This issue of Biomedical Journal explores emerging perspectives across neuropsychiatry, #metabolism, #aging, regenerative medicine, #artificialintelligence & chronic inflammatory disease www.sciencedirect.com/science/arti... #OpenAccess #AI #MedSky
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Biomedical Journal @biomedj.bsky.social · 28/05/2026
Multi-omics insights into uric acid #metabolism: from genetics to epigenetics, transcriptomics, and metabolomics in cardiometabolic disease www.sciencedirect.com/science/arti... #OpenAccess #MedSky #Hyperuricemia
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Rima I Anabtawi @rimaanabtawi.bsky.social · 25/05/2026
Ugandan health authorities reported two new Ebola cases, bringing the number of infections there to seven as the number of suspected cases in the Congo continued to rise. www.cbsnews.com/news/ebola-u...
cbsnews.com
Ebola outbreak death toll climbs in Congo as new infections confirmed in Uganda
The WHO chief says there have been 220 suspected deaths in the ongoing Ebola outbreak as Ugandan health authorities report two new Ebola infections.
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Biomedical Journal @biomedj.bsky.social · 24/05/2026
Distinct subtypes of kidney transplant-associated urothelial carcinomas harboring BK polyomavirus integration and aristolochic acid mutational signatures www.sciencedirect.com/science/arti... #OpenAccess #cancer #diagnosis #MicroSky #MedSky
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TRAstonDrs @castltrastondrs.medsky.network · 24/05/2026
#Medsky🧪 #IDsky #Neurosky #publichealth Extensive evidence indicates that the prevalence, incidence, symptoms, trajectory and severity of many neurological and psychiatric diseases and disorders are sex-specific or sex-biased. The preponderance of autoimmune disorders such as
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