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Mark Davison

@bigexperiment.bsky.social

2.1K followers 6.7K following 117 posts

Tech CEO, science podcaster, investor, runner, cyclist. Solving temperature control (www.grantinstruments.com). Interviewing biotech founders on "The Big Experiment" thebigexperiment.buzzsprout.com/231…

Posts Replies Media

Mark Davison @bigexperiment.bsky.social · 26/02/2025

Having a bad day? My lucky Ace of Spades banana can help. Scientifically endorsed by Lemmy's ghost. 🧪

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Mark Davison @bigexperiment.bsky.social · 03/02/2025

Grant Instruments is making a customised precision water bath, with 200 litre capacity, for a top UK university. For reference, that's the volume of a UK wheelie bin, as modeled by the charity runner below. DM me if you need unusual temp control solutions in your lab 🧪

Sunderland bin man (refuse collector) Deano Franciosy gets ready to take on 26.2 miles London Marathon with wheelie bin strapped to his back

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Mark Davison @bigexperiment.bsky.social · 25/01/2025

If you're working on organoids, DM me to improve workflow and yields, using controlled, reproducible freeze-thaw processes.🧪

Controlled rate freeze-thaw device from Grant Instruments. No liquid nitrogen required.

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Mark Davison @bigexperiment.bsky.social · 03/01/2025

Winter dusk, crescent moon, Venus (above moon). 🧪

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Mark Davison @bigexperiment.bsky.social · 24/12/2024

Science doesn't stop for Christmas. Kudos if you're a Cold Room Queen, or Genetics Genie, tending to your experiments over the holidays. See if you can invent pure green, like this guy. 🧪

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Mark Davison @bigexperiment.bsky.social · 23/12/2024

Chemistry in cells isn't like in buffer. Cells are crowded. Diffusion and reaction rates vary with temp. Accuracy is vital! Check your setup: +/-2C won't cut it. www.grantinstruments.com/product-grou... Mycoplasma genitalium image: Martina Maritan, Scripps Research. ccsb.scripps.edu/gallery/myco...

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Mark Davison @bigexperiment.bsky.social · 23/12/2024

Bacteriophage T4 infecting E. coli. Beautiful illustration by by David S. Goodsell, RCSB Protein Data Bank and Scripps Research. doi: 10.2210/rcsb_pdb/goodsell-gallery-048

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Mark Davison @bigexperiment.bsky.social · 22/12/2024

Last long run (16km) this morning before Christmas. Now for a week of unscientific carb-loading🧪

Mark in running gear, with sunrise in background, on a cold Sunday morning

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Mark Davison @bigexperiment.bsky.social · 16/12/2024

Synthetic Biology - the Live Album! 🧬 Meat without killing animals 🧬 Helping crops adapt to climate change 🧬 Using bacteria to clean up contaminated soils 🧬 New vaccines before pandemics My latest podcast, recorded at Synthetic Biology UK 2024 last month 🧪 open.spotify.com/episode/7q15...

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Mark Davison @bigexperiment.bsky.social · 15/12/2024

"I saw the crescent. You saw the whole of the moon" The Waterboys, 1985*. Bright full moon last night, even through cloud. Great corona effect not, quite caught by my phone. 🧪 *Look it up on Spotify. A belter of a tune for a Sunday morning.

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Mark Davison @bigexperiment.bsky.social · 11/12/2024

Synthetic Biology podcast ep coming Monday! I'll cover this very wide field in "The Big Experiment" (hear prev. eps: open.spotify.com/show/7bFVmqI...). New shows every 2 wks. [Diagram: B. Ghosh, Emerg. Top. Life Sci. (2022) 6 (6): 619–627]

Diagram showing various artificial cell technologies and their applications

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Mark Davison @bigexperiment.bsky.social · 04/12/2024

Please don't thaw critical cell lines in water baths, Cillian! Grant Instruments' solid-state ❄️CRFT❄️ thaws cells (or anything else) gently, reproducibly, with no liquids to contaminate them. It also freezes to -100C, with exquisite control. All with less benchtop footprint than a water bath. 🧪

Leo Di Caprio and Cillian Murphy discuss cell biology

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Mark Davison @bigexperiment.bsky.social · 03/12/2024

We make lab equipment. Especially high-precision heating / cooling / freezing / thawing for life science and biomedical research. Message me with any tricky temp control challenges and I'll try to help. No hard sell. 🧪 www.grantinstruments.com

Controlled rate freeze thaw device from Grant Instruments

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