Cell-based models of the human cortex transplanted into mice produce neurons that are inaccessible in vitro, and could enable scientists to link brain injury to behaviour.

The developing human cortex is composed of diverse cell types, but how nutrient metabolism shapes their fate has remained unclear. This study maps the metabolic landscape of the developing human corte...

Tumor organoid models offer new insight into how the brain and immune system shape cancer behavior.

Characterization of cell type emergence during human cortical development, which enables unique human cognition, has focused primarily on anatomical and transcriptional characterizations. Metabolic pr...