ME/CFS belastet nicht nur die Erkrankten selbst, sondern beeinträchtigt auch das Leben der Angehörigen. Eine Betroffene berichtet - Folge #1693

Mein Partner war sportlich, arbeitete, kümmerte sich um unsere Kinder. Dann bekam er eine Diagnose: ME/CFS. Und ich eine neue Rolle. Sie könnte nicht traditioneller sein

Diaz-del-Olmo et al. reveal how a Salmonella virulence protein alters the transcriptional layout of infected macrophages through hyperactivation of a transcription factor and coordinated chromatin remodeling.

Wie geht es der ME/CFS-Community nach dem öffentlich gewordenen Fall eines assistierten Suizids? Wir sprechen mit Betroffenen und Experten.

Indivisible is a nationwide movement of millions of people working to stop the rise of authoritarianism in the United States and to demand a real democracy. We believe that politics is too important t...

A frame-by-frame assessment of actions by Alex Pretti and the two officers who fired 10 times shows how lethal force came to be used against a target who didn’t pose a threat.

Pathogens secrete effector proteins to promote virulence. Despite their recognition by barley Mla resistance genes, the structurally-related Blumeria hordei ( Bh ) AVRA effectors are maintained in the...

Angesichts von Sperren und Millionenstrafen setzt X Scheinmaßnahmen gegen Missbrauchsdarstellungen. Warum die App nicht längst aus den Stores geflogen ist, bleibt rätselhaft

Fusion genes involving KMT2A rearrangements are frequent oncogenic drivers of acute myeloid leukaemia (KMT2A-r AML) but the cell of origin remains unclear. Here, using preclinical models of EVI1 posit...

Conventional methods have failed to simultaneously integrate one-dimensional transcriptional studies with three-dimensional chromatin architecture. In this issue, Li et al. present Hi-Coatis, an antibody- and probe-free approach that seamlessly maps active transcription-associated chromatin networks with high sensitivity and spatial resolution.

Bücherfreund:innen aufgepasst! In Wien-Penzing entsteht das BuchQuartier, ein genossenschaftliches Buchcafé. Infoveranstaltung am 23.9.2025. Mehr dazu hier:

imageimageMechanisms underpinning resistance of tumorigenic cells to inactivation of oncogenic KRAS remain to be fully understood. This study shows that STAT3 sustains tumorigenicity of pancreatic cancer cells depleted of the mutant KRAS driver. ...

Key Points. FOXO transcription factors and the GSK3 kinase are pivotal tumor suppressors restrained by AKT activity in MM cells.FOXO and GSK3 destabilize M

Dietary cysteine enhances intestinal stem cell-mediated intestinal repair following injury by promoting CD8 T cell-regenerative immune responses.

Immune checkpoint blockade activates T cell immunity by reprogramming the STAT3 and STAT5 transcriptional pathways in dendritic cells, and STAT3 degradation is effective for treating tumours of multiple cancer types in mouse models.