This variant is typically intermixed with many wildtype EGFR ecDNAs that hitchhike on strongly positively selected variants and therefore maintaining a mixed state if ecDNA wildtype and variants in the tumour population
Benjamin Werner
@benjaminwerner.bsky.social
795 followers 410 following 336 posts
Es irrt der Mensch, solang er strebt. Group Leader at Barts Cancer Institute in London. Working on somatic evolution, ecDNA, clonal haematopoiesis… www.bartscancer.london/staff/dr-ben… Contact: b.werner@qmul.ac.uk
