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Michael Roach

@beardymcjohnface.bsky.social
216 followers 258 following 2 posts

He/him; bioinformatician; enthusiast brewer and certified beer judge; running stuff on your head node.

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Reposted by Michael Roach
Vijini Mallawaarachchi @vijinim.bsky.social · 26/07/2026
🚀 MetaCoAG v1.3.0 is out! This release adds faster FASTA processing, NumPy feature storage, better multiprocessing, cleaner graph traversal, and resumable runs. Benchmarks show up to 28.7x faster runtime and up to 56% lower peak memory. (1/n) #bioinformatics #metagenomics #assemblygraph
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Reposted by Michael Roach
Rob Edwards @linsalrob.bsky.social · 22/07/2026
Starting with the DNA sequence of a #phage genome, #PholdAPhage will create a 3D reconstruction of the complete phage, almost like you did cryoEM on it! Check out Renee's awesome software github.com/reneegreen81... to assemble unknown phage particles one protein at a time
A computer generated 3D reconstruction of a phage, based solely on its genome sequence. For this image, we started with the genome, and used PholdAPhage to create the structures. Colours are based on pLDDT scores.
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Stevie Ped @smped.bsky.social · 17/06/2026
SA politicians who just voted to restrict access to women's health care. They lost the vote but might be worth remembering who they are.
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Cédric Scherer @cedricscherer.com · 28/10/2025
🦧📉 Why are there colorful apes in my #dataviz workshops? 📸 The photo taken years ago by my friend Richard Strozynski has become a tradition in my client projects and courses. I like to recolor it with different palettes to show how palette design affects perception. Thread 👇
A photograph of two apes (mother holds her child) and three recolored versions of the same phtograph using three palettes of different quality.
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Reposted by Michael Roach
Stefano Mangiola @stemang.bsky.social · 14/10/2025
ABACBS/BioC Asia 2025 Workshops are coming! @ Adelaide 27-28 November. Join us in November for two days of deep-dive sessions on scalable bioinformatics, spatial omics, AI-driven genomics, and more blackochrelabs.au/abacbs2025_w... #Bioinformatics @abacbs.bsky.social @bioconductor.bsky.social
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Katelyn Burns @katelynburns.com · 23/09/2025
i have to say, as a trans journalist who has covered the "trans debate" for about a decade now, there is no daylight between how the trump administration and conservatives lie about tylenol and autism and how they've lied about youth trans care.
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Barack Obama @barackobama.bsky.social · 18/09/2025
After years of complaining about cancel culture, the current administration has taken it to a new and dangerous level by routinely threatening regulatory action against media companies unless they muzzle or fire reporters and commentators it doesn’t like.
yahoo.com
Let’s be clear about what happened to Jimmy Kimmel
Trump’s most brazen attack on free speech yet.
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Reposted by Michael Roach
Jess Calarco @jessicacalarco.com · 14/09/2025
Yesterday's piece from @jamellebouie.net is the only high-profile piece I've seen that specifically discusses the watchlist, its effect on academics, and its effect on public attitudes toward academia as a whole. (gift link) www.nytimes.com/2025/09/13/o...
nytimes.com
Opinion | Charlie Kirk Didn’t Shy Away From Who He Was. We Shouldn’t Either.
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Reposted by Michael Roach
Anita Tarasenko @anitatarasenko.bsky.social · 09/09/2025
🚨New Review Out🚨 We explore how phage-antibiotic synergy can dismantle efflux-driven resistance in multidrug-resistant ESKAPEE pathogens. By reprogramming bacterial defences, phages offer a precision strategy to restore antibiotic efficacy. journals.asm.org/doi/10.1128/...
journals.asm.org
Reprogramming resistance: phage-antibiotic synergy targets efflux systems in ESKAPEE pathogens | mBio
Antimicrobial resistance (AMR) is one of the greatest threats to global health. If unaddressed, it is projected to cause over 39 million cumulative deaths globally by 2050 (1). While resistance is a b...
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Reposted by Michael Roach
Susie Grigson @susiegriggo.bsky.social · 30/07/2025
🚨 New preprint 🚨 My phage annotation tool, Phynteny, finally has a preprint and a brand new version powered by a cool AI transformer architecture and protein language models! #phagesky www.biorxiv.org/content/10.1...
biorxiv.org
Synteny-aware functional annotation of bacteriophage genomes with Phynteny
Accurate genome annotation is fundamental to decoding viral diversity and understanding bacteriophage biology; yet, the majority of bacteriophage genes remain functionally uncharacterised. Bacteriopha...
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bioRxivpreprint @biorxivpreprint.bsky.social · 27/07/2025
LeGO-Teknik reveals that the neurogenesis pathway is a clone-specific hallmark of brain metastasis in breast cancer www.biorxiv.org/content/10.1101/202…
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Reposted by Michael Roach
Rob Edwards @linsalrob.bsky.social · 07/07/2025
PhD opportunities at @flindersuniversity.bsky.social in Adelaide, Australia's most liveable city, to study genetics in #phage We will also have genetics #postdoc positions too! #microsky #phagesky www.linkedin.com/pulse/phd-pr...
linkedin.com
PhD Project: Discovering Novel Mechanisms of Phage Genome Evolution
We are looking for an awesome PhD student to join our research team to investigate how bacteriophages (phages) generate targeted mutations that enable them to evolve and infect new bacterial hosts. Yo...
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Susie Grigson @susiegriggo.bsky.social · 07/07/2025
We've folded a lot of proteins! You can see some of them here @linsalrob.bsky.social @gbouras13.bsky.social
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Rob Edwards @linsalrob.bsky.social · 26/06/2025
Very honoured and excited to have been awarded an ARC Laureate Fellowship today. Exciting things to come! #FL25 rms.arc.gov.au/RMS/Report/D...
rms.arc.gov.au
Research Management System - Scheme Round Statistics for Approved Applications - Australian Laureate Fellowships 2025 round 1
RMS is the ARC's Research Management System, a web-based system used by eligible researchers to prepare and submit research proposals and assessments under the ARC National Competitive Grants Program ...
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Feargal Ryan @feargalr.bsky.social · 22/04/2025
Manuscript out now in Briefings in Bioinformatics! TaxSEA: rapid interpretation of microbiome alterations using taxon set enrichment analysis and public databases. #microbiome #metagenomics academic.oup.com/bib/article/...
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Wytamma @wytamma.bsky.social · 26/11/2024
Excited to share my first JOSS publication 🎉 Snk: A #Snakemake CLI and Workflow Management System joss.theoj.org/papers/10.21...
joss.theoj.org
Snk: A Snakemake CLI and Workflow Management System
Wirth et al., (2024). Snk: A Snakemake CLI and Workflow Management System. Journal of Open Source Software, 9(103), 7410, https://doi.org/10.21105/joss.07410
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Bhavya N P @npbhavya.bsky.social · 13/12/2023
🎉 Excited to introduce #SPHAE! Our new workflow for phage genome analysis generates complete genomes, annotations, & comprehensive summaries of genome features. Check it out: github.com/linsalrob/sphae #phagesky @linsalrob.bsky.social
github.com
GitHub - linsalrob/sphae: NEW!!! Phage annotations and predictions. A spae is a prediction or forete...
NEW!!! Phage annotations and predictions. A spae is a prediction or foretelling. We'll foretell you what your phage is doing! - GitHub - linsalrob/sphae: NEW!!! Phage annotations and prediction...
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Michael Roach @beardymcjohnface.bsky.social · 22/11/2023
Do invite codes just accumulate over time?
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