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Reposted by Biochemistry Center Cologne

Marius Lemberg @marius-lemberg.bsky.social · 15h

Our Review on intramembrane proteolysis is out in @cp-trendsbiochem.bsky.social! We look at how proteases, substrates, and membranes work together to recognize and process membrane proteins. Great fun putting this together with Dönem Avci and Susi Steigleder! www.sciencedirect.com/science/arti...

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Reposted by Biochemistry Center Cologne

Universität zu Köln @unicologne.bsky.social · 02/10/2026

🎉 We are excellent The #UniCologne has succeeded with its proposal “Neue Universität: Continuous Change – Successful Renewal” and has been awarded the status of a ‘University of Excellence’ as part of the Excellence Strategy of the Federal and State Governments ➡️uni.koeln/SWUK7

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Reposted by Biochemistry Center Cologne

Journal of Cell Science @jcellsci.bsky.social · 09/09/2026

Susanne Steigleder, Julian Nüchel @jnuechel.bsky.social, Marius Lemberg @marius-lemberg.bsky.social and colleagues identify a Golgi-bypass secretion mechanism for proTGFα involving TMED9 and GRASP65. journals.biologists.com/jcs/article/...

Proposed mechanism of TMED9- and GRASP65-induced unconventional proTGFα secretion.

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Reposted by Biochemistry Center Cologne

Marius Lemberg @marius-lemberg.bsky.social · 04/09/2026

We’re looking for a new colleague in Cologne! A permanent 75% position coordinating and developing our Biochemistry teaching - with plenty of opportunity to teach and shape the curriculum. Must be able to teach in German 🇩🇪 Please share! jobs-uk-koeln.onlyfy.jobs/de/job/ztehy...

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Reposted by Biochemistry Center Cologne

Marius Lemberg @marius-lemberg.bsky.social · 01/09/2026

Our new preprint is out! We show that the intramembrane protease RHBDL4 targets multiple cargo receptor families, linking proteolytic remodeling of cargo receptor networks to the regulation of secretory pathway flux. Great work led by Susi Steigleder, @jnuechel.bsky.social and the team!

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Biochemistry Center Cologne @bccologne.bsky.social · 30/07/2026

🎉 Congratulations to Susanne Steigleder on her first-author publication in JCS! The study identifies a TMED9/GRASP65-dependent Golgi-bypass pathway for proTGFα, revealing new insights into unconventional protein secretion. Congratulations to the entire team! 👏 journals.biologists.com/jcs/article-...

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Biochemistry Center Cologne @bccologne.bsky.social · 23/07/2026

Congratulations to our junior group leader @bccologne @unicologne Julian Nüchel on this exciting preprint! The study identifies TANGO1 as a selective ECM cargo receptor, revealing new insights into ER export and skeletal dysplasia. A collaborative milestone from FOR2722

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Reposted by Biochemistry Center Cologne

Julian Nüchel @jnuechel.bsky.social · 27/04/2026

💥 New publication from the Demetriades and Nüchel groups– final version now online in EMBO reports! This Tour de force wouldn’t have worked out without the amazing support from our collaborators and core facilities!

link.springer.com

GRASP55 maintains lysosome function by controlling sorting of lysosomal enzymes at the Golgi - EMBO Reports

Lysosomes are multifunctional organelles that play important roles in cellular recycling, signaling, and homeostasis, relying on precise trafficking and activation of lysosomal enzymes. While the Golg...

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Biochemistry Center Cologne @bccologne.bsky.social · 23/09/2025

Congratulations to Günter Schwarz and his team at the Institute of Biochemistry @chemunicologne.bsky.social not the Medical Biochemistry this time 😉

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Reposted by Biochemistry Center Cologne

Universität zu Köln @unicologne.bsky.social · 22/08/2025

🔬 Research Team Discovers Potential Treatment for Rare Childhood Disease 🧬 A team at @bccologne.bsky.social has made a significant breakthrough in the treatment of the STING-associated vasculopathy with onset in infancy (SAVI). The SAVI is a severe genetic disorder that is currently incurable.

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Reposted by Biochemistry Center Cologne

Achim Zolke 🇪🇺 @zolke.bsky.social · 19/01/2025

This is a turning point. We Europeans have the power to push X into irrelevance across our continent. Freeze or delete your accounts now. Media, it’s time to stop citing X. Dozens of universities are leading the way. Let’s limit Elon Musk’s influence in 🇪🇺. #eXit #SciXit #Democracy

Article on the mass eXit of German universities from plattform X in protest against anti-democratic discourse pushed by Elon Musks algorithms.

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Biochemistry Center Cologne @bccologne.bsky.social · 18/12/2024

The latest work by Alvise Schiavinato, Gerhard Sengle and coworkers @bccologne.bsky.social @uniklinikkoeln.bsky.social identified EMILINs as important markers to monitor rearrangements of the dermal #ECM architecture induced by aging and pathological conditions. rdcu.be/d33Z3

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Biochemistry Center Cologne @bccologne.bsky.social · 18/12/2024

Exciting twist on membrane protein quality control. Congratulations to Nik Sergejevs and Pedro Carvalho @dunnschool.bsky.social as well to all contributing authors including Dönem Avci and Marius Lemberg @bccologne.bsky.social

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Reposted by Biochemistry Center Cologne

CECAD Cologne @cecad.bsky.social · 04/12/2024

Hello World! ⭐ We’re CECAD Cologne, a cutting-edge research center dedicated to unraveling the mysteries of #Aging and promoting healthier, longer lives! Follow us for the latest discoveries, insights, and events in #AgingResearch! 🧬🔬👩‍🔬 www.cecad.uni-koeln.de

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Biochemistry Center Cologne @bccologne.bsky.social · 25/11/2024

Promising new treatment approach for severe COVID-19! Clinical trial with Fas ligand blocker shows faster recovery & reduced mortality. Approach targets immune overreaction, potentially effective against future viruses too. Read more t.ly/6kalU

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Biochemistry Center Cologne @bccologne.bsky.social · 25/11/2024

Liquid droplets cut membranes without protein scissors. A study led by Roland Knorr and an international team shows that tiny liquid droplets, known as biomolecular condensates, cut membranes of plant cells without the need for specialized proteins. Read more www.nature.com/articles/d41...

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