iiinova — where your digital self keeps evolving

Christopher A. Baker @bakermind.bsky.social · 20/05/2026

Completely moved to hear the emotion in your voice, @profgalloway.com, regarding alleged abuse of Belgian Malinois and prisoners. The notion that anyone could abuse the bond of a Malinois to perpetuate heinous acts is disgusting. They will die for you. Mine is one of the best things to happen to me

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Christopher A. Baker @bakermind.bsky.social · 30/12/2025

He died rather soon after this show. Then I knew I had seen something of importance

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Christopher A. Baker @bakermind.bsky.social · 30/12/2025

Looking back at the setlist, it was killer. Help->Slipknot!->Franklin's New Minglewood Blues Easy to Love You Peggy-O Masterpiece Brown Eyed Women Cassidy Deal China Cat Sunflower I Know You Rider Looks Like Rain Terrapin Station drums The Other One Morning Dew The Weight

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Christopher A. Baker @bakermind.bsky.social · 30/12/2025

Dating myself, but I'm always excited to hear a streaming recording of a show where I was present. My voice from the past is coming back to me

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Christopher A. Baker @bakermind.bsky.social · 09/12/2025

They once told you to never read the comments, but one of the best parts of social media nowadays is reading the comments on official government posts

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Christopher A. Baker @bakermind.bsky.social · 17/11/2025

Importantly, Kidd et al. IMPROVED the field and led to real genetic causes of autism or psychiatric disorders. But there are certainly environmental causes of childhood psychiatric disorders too. So the goal (hopefully) is not to necessarily disprove, but instead to IMPROVE 4/4

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Christopher A. Baker @bakermind.bsky.social · 17/11/2025

Some disagree: one of my mentors warned against spending too much effort to disprove flawed assertions. Gotta light a candle, perhaps. Kidd not only cleaned up the literature but made seminal contributions (importance of considering diversity in genetic studies, ironically) 3/

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Christopher A. Baker @bakermind.bsky.social · 17/11/2025

It's common for a field to develop "trendy" topics (I'm old enough to remember nNOS) and also trendy to tear down trendy topics. Such criticism is still important (e.g. Ken Kidd helped a lot by removing spurious genetic association studies in psychiatric disease) 2/

media.tenor.com

a cartoon character from south park says yeah a lot of the guys here are posers so you gotta be careful .

ALT: a cartoon character from south park says yeah a lot of the guys here are posers so you gotta be careful .

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Christopher A. Baker @bakermind.bsky.social · 17/11/2025

I've been a fan of @wiringthebrain.bsky.social for many years and notice that he spent a lot of time criticizing epigenetics and now he's laying into gut-brain axis. 🧵 1/

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Christopher A. Baker @bakermind.bsky.social · 17/11/2025

Happy neuroscience? Saw this and thought you might try it. It involves several things you love youtu.be/bHOE-5uR3Xg?...

youtu.be

Crystal-Clear Coffee Negroni : A Game-Changing Technique

YouTube video by Truffles On The Rocks

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Christopher A. Baker @bakermind.bsky.social · 16/11/2025

This essential truth applies to vaccine debates, political issues, and public trust of scientists: facts only helps humans justify the choice they are already making. To persuade anyone you must appeal to personal safety and identity first. youtu.be/dtxjpLCVTMQ?...

youtu.be

Facts Don't Win Buy-In (Learn What Actually Does)

YouTube video by Dr. Grace Lee

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Christopher A. Baker @bakermind.bsky.social · 06/11/2025

Which Renaissance painting is this

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Christopher A. Baker @bakermind.bsky.social · 06/10/2025

Seems like those suing are non-profits, and those not suing are corporations. What's worth exploring is whether tech STARTUPS will sue, because the $100K system favors tech giants that can easily absorb the excess cost

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Christopher A. Baker @bakermind.bsky.social · 06/10/2025

My wife keeps telling me about that place. We're in Connecticut now and it seems so close but also so far if you know what I mean

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Christopher A. Baker @bakermind.bsky.social · 06/10/2025

... the right has been quite adept at this, simply bathing in hypocrisy as required to achieve the ends of destroying progressive and centrist ideals. Should the left take the same road? Or will holding to their ideals actually be the better choice for attracting support based on authenticity?

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Christopher A. Baker @bakermind.bsky.social · 06/10/2025

It's interesting work that highlights a typical poltical problem: ideology versus pragmatism. Making an ethical stand is important, but some consider that such stands might be futile unless power is achieved through pragmatic actions that might require compromising one's ethics...

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Christopher A. Baker @bakermind.bsky.social · 06/10/2025

What's the point? It's deserted? That's capitalism at work I guess

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Christopher A. Baker @bakermind.bsky.social · 02/10/2025

💯 When not private equity, it's often just greed or topheaviness

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Christopher A. Baker @bakermind.bsky.social · 30/09/2025

The one critique that shocked me was: "The NIH Director has never been the PI on an NIH grant". Not sure if that's true but I'm not surprised

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Christopher A. Baker @bakermind.bsky.social · 13/09/2025

So glad I've spent the last couple of days in the woods immersed in science and teamwork with @virusesimmunity.bsky.social, @yalecii.bsky.social, and colleagues, unplugged from media for the most part

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Christopher A. Baker @bakermind.bsky.social · 06/09/2025

Lol it's just for the photo - intent was to get the Sound in the background. Definitely not keeping the glass on that railing

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Christopher A. Baker @bakermind.bsky.social · 06/09/2025

That was Dennis Kucinich's idea. At least it was novel. Trump just went back to his favorite era: 1938. I remember last week when Trump said he stopped 7 wars and should get the Peace Prize; now he's all in on war

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Christopher A. Baker @bakermind.bsky.social · 06/09/2025

I made a chartreuse swizzle to start

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Christopher A. Baker @bakermind.bsky.social · 06/09/2025

A farewell to the summer with a suggestion from @anderseriksson.bsky.social : it's not Mountain Dew; it's a chartreuse swizzle (Chartreuse, pineapple juice, lime juice and falernum), which is orders of magnitude more expensive (glass from Cognitive Surplus)

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Christopher A. Baker @bakermind.bsky.social · 13/08/2025

Thank you for reaching out. Yes some people were concerned about what I had disclosed, and others began to harass me just for being a researcher in the field. I deactivated the account to remove the previous disclosures and take a break from some of the haters

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Christopher A. Baker @bakermind.bsky.social · 09/07/2025

This paper is suggestive but not conclusive - it shows that dumping spike protein on human retina cultures induces beta amyloid that colocalizes with spike, and that similar colocalization is detected in postmortem retina from COVID patients. Very thought-provoking nevertheless

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Christopher A. Baker @bakermind.bsky.social · 09/07/2025

intersection of SARS-CoV-2 and beta amyloid gets at concepts that have bugged me for years: 1) that amyloid deposition is an antecedent of infection or host defense, and 2) that spike protein itself may have amyloidogenic properties. science.org/doi/epdf/10....

science.org

SARS-CoV-2 induces Alzheimer’s disease–related amyloid-β pathology in ex vivo human retinal explants and retinal organoids

You have to enable JavaScript in your browser's settings in order to use the eReader.

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Christopher A. Baker @bakermind.bsky.social · 27/06/2025

I made a post earlier about Fluorescence Friday, but some people say it's Fascist Friday because of the ouster of UVA president... to which I say I'm still going to do science for the public interest for as long as I can

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Christopher A. Baker @bakermind.bsky.social · 27/06/2025

above we see the Subfornical Organ dangling into the 3rd ventricle of the brain, flanked by choroid plexus cells making cerebrospinal fluid. Cell nuclei in blue, with in situ hybridization for genes marking macrophage subsets: F13a1 (yellow), Cx3cr1 (magenta), and Aif1 (cyan)

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Christopher A. Baker @bakermind.bsky.social · 27/06/2025

People consider the pineal gland to be a Third Eye. Maybe they should have focused on the Subfornical Organ instead - also in the middle of the brain, but with a newly acknowledged pathway for T cell traffic between the gut and the brain that affects behavior #FluorescenceFriday

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Christopher A. Baker @bakermind.bsky.social · 25/06/2025

This seems like a general principle in nature and not mysterious: early rate of return leads to a large inequity over time. That applies to success, wealth, and viral replication www.nature.com/articles/d41...

nature.com

Early grant success attracts more funding: study of 100,000 applicants hints at why

Largest study of its kind explores the ‘Matthew effect’ in research.

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Christopher A. Baker @bakermind.bsky.social · 24/06/2025

My wife and I have fantasized about tattoos for years. They seemed like a luxury item, and now that tattoos are being used as an excuse for CBP/ICE harassment, we probably won't get any. (I'm a citizen born abroad; she is a naturalized citizen)

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Christopher A. Baker @bakermind.bsky.social · 16/05/2025

For this #fluorescencefriday I've got my go-to image of small pain sensing nerve fibers and collagen in the toe, now selected as one of many examples of the "Beauty of Science" for the current exhibit at @yaleschoolofmed.bsky.social

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Christopher A. Baker @bakermind.bsky.social · 09/05/2025

A Bouvaldier, because it's been that kind of week

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Christopher A. Baker @bakermind.bsky.social · 25/04/2025

I just want to thank @profgalloway.com for this uplifting commentary on American universities as engines of innovation, as well as his recognition of PhDs as incredible contributors to society and human knowledge. Have a nice weekend youtu.be/r4N7BKtgJHo?...

youtu.be

How Trump Plans to Incentivize a Baby Boom | Pivot

YouTube video by Pivot with Kara Swisher and Scott Galloway

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Christopher A. Baker @bakermind.bsky.social · 25/04/2025

Today's activity: not exactly Maiden or Master of Puppets

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Christopher A. Baker @bakermind.bsky.social · 16/04/2025

"COVID-19 has killed more Americans than all the wars in the 20th century combined" ~ Shane Crotty, La Jolla Institute for Immunology

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Christopher A. Baker @bakermind.bsky.social · 16/04/2025

Has importing python packages been a major problem to making your code great? Now you can impose TARIFFS on whenever you import a package github.com/hxu296/tariff

github.com

GitHub - hxu296/tariff: The official repository for tariff

The official repository for tariff. Contribute to hxu296/tariff development by creating an account on GitHub.

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Christopher A. Baker @bakermind.bsky.social · 14/04/2025

Nominations open for a prize in nanometer-scale connectomics, in honor of my friend Jennifer N. Bourne www.sfn.org/careers/awar...

sfn.org

Jennifer N. Bourne Prize in Neuronal and Synaptic Structure and Function

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Christopher A. Baker @bakermind.bsky.social · 14/04/2025

If New Haven is Avelo Air's most important market, they might have shot themselves in the foot by signing up to conduct ICE deportation flights (and then blaming New Haven for their problems) www.nhregister.com/news/article...

nhregister.com

Avelo's defense of ICE deportation flights targets Tweed, shows tension between airline and airport

Avelo's CEO says the airline needs to fly ICE deportation charters to shore up its bottom line because of Tweed Airport issues

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Christopher A. Baker @bakermind.bsky.social · 05/04/2025

Weird to use ACE2 for Omicron studies - it's not necessary to use humanized transgenic receptor, but I'll have to read the paper. Maybe the transgenic expression alters the infection course

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Reposted by Christopher A. Baker

Data Report @datareport.bsky.social · 27/03/2025

Whooping cough cases continue to surge in Seattle, and across Washington mynorthwest.com/local/whoopi...

mynorthwest.com

Whooping cough surging in Washington and Seattle

Whooping cough cases continue to surge in Seattle and across Washington state.

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Reposted by Christopher A. Baker

Alexandra Witze @alexwitze.bsky.social · 27/03/2025

We polled Nature readers to ask if they were thinking of leaving the US for jobs abroad. Three-quarters of them (who said they were US-based scientists) said yes. 🧪 www.nature.com/articles/d41...

nature.com

75% of US scientists who answered Nature poll consider leaving

More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.

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