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Auclair Lab

@auclairlab.bsky.social
154 followers 126 following 135 posts

We explore many fields of chemistry and biology (many of them concerning enzymes). Located at McGill University, Montreal. Student-ran account: posts not by Dr. Auclair, DMs not monitored. RP/follow ≠ endorsement. www.auclair-group.mcgill.ca

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Auclair Lab @auclairlab.bsky.social · 29/09/2026
🚨 NEW PAPER ALERT 🚨 In BBA Proteins and Proteonomics, fresh from the Auclair lab, Yuqin investigates the fractal kinetics of moist-solid enzymatic PET depolymerization by HiC. Congratulations to Yuki! doi.org/10.1016/j.bb...
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Auclair Lab @auclairlab.bsky.social · 21/09/2026
McGill students are invited to Green Chemistry McGill's 5th annual Global Conversation on Sustainability, happening this Friday at 10:30 AM! In-person and virtual attendance are both possible. (But between the two of us, we're pretty excited about the food, too...!)
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Auclair Lab @auclairlab.bsky.social · 17/09/2026
🚨 NEW PAPER ALERT 🚨 We're going back-to-back! In ACS Sustain. Chem. Eng., Nu Thuy Tu Ton and Hannah Girard investigate mechanoenzymatic depolymerization of alginate. This method obtained lower-MW oligosaccharides with narrower polydispersity. Congrats to Tu and Hannah! doi.org/10.1021/acss...
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Auclair Lab @auclairlab.bsky.social · 15/09/2026
Check out the graphical abstract! Congrats to @canvasblue.bsky.social and Jake on the great work
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Auclair Lab @auclairlab.bsky.social · 22/06/2026
Ryan and Luis of the Auclair Lab had a great experience at the CCVC/CGCC Summer Camp, learning about the cutting edge of green chemistry and catalysis in Quebec!
photo credits: Amir Nasreddine
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Auclair Lab @auclairlab.bsky.social · 05/06/2026
We had a fantastic time at CSC #x2026!
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Auclair Lab @auclairlab.bsky.social · 21/05/2026
We're happy to announce that two of our articles were certified as top viewed articles for 2025! Dr. Ali Zaker's work on the microstructure of PET and Dr. Blue Lan's TBD-catalyzed synthesis of 3-hydroxyisoindolin-1-ones were recognized in ChemSusChem and EurJOC respectively. Links below!
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Auclair Lab @auclairlab.bsky.social · 14/05/2026
We were delighted to host Prof. Hal Alper and Amelia Bergeson from @utaustin.bsky.social to Montreal this week! Prof. Alper is a longtime collaborator of ours and gave a fascinating talk about engineering biology.
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Auclair Lab @auclairlab.bsky.social · 07/05/2026
The Auclair lab had a great time at the 2026 Open Plastic Symposium hosted at @queensuresearch.bsky.social! Jane and Ryan (not pictured) gave oral presentations, while Alana and Natalia presented posters.
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Auclair Lab @auclairlab.bsky.social · 17/04/2026
Important lab cleaning duty: the popcorn machine
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Auclair Lab @auclairlab.bsky.social · 07/04/2026
Spinning some lysate. For comparison, F1 engines hit a maximum of 15,000 rpm (well, maybe they're not going that high this year...) #chemsky
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Auclair Lab @auclairlab.bsky.social · 06/02/2026
It's a full queue kind of day #chemsky
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Auclair Lab @auclairlab.bsky.social · 22/01/2026
Freezer defrosting day means freezer sorting day #chemsky
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Auclair Lab @auclairlab.bsky.social · 19/01/2026
First thiol smell of the new year. And it's not even a particularly noxious one! #chemsky
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Auclair Lab @auclairlab.bsky.social · 05/01/2026
We're officially back for the new year. The built-up freezer ice looks so neat it's almost a shame to de-ice it all.
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Auclair Lab @auclairlab.bsky.social · 05/12/2025
This is our freezer for the next few hours #chemsky
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Auclair Lab @auclairlab.bsky.social · 26/11/2025
Prof. Auclair presented at the McGill Interdisciplinary Initiative in Infection and Immunity (MI4) annual symposium last week!
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Auclair Lab @auclairlab.bsky.social · 17/11/2025
Come find us at @concordia.ca Loyola campus for CBGRC this Friday!
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Auclair Lab @auclairlab.bsky.social · 30/10/2025
NEW PREPRINT: An extensive structure-activity relationship investigation of pantetheinamides and their ability to inhibit Salmonella typhimurium. We investigate the mechanisms of action of these compounds and their use with in vivo mouse models. doi.org/10.1101/2025...
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Auclair Lab @auclairlab.bsky.social · 23/10/2025
Here's some more balanced centrifuge arrangements #chemsky
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Auclair Lab @auclairlab.bsky.social · 08/10/2025
Good Wordle yesterday.
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Auclair Lab @auclairlab.bsky.social · 12/09/2025
Many members of the Auclair lab hosted and attended the student-led Careers After Chemistry conference! #CAC2025 #chemsky
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Auclair Lab @auclairlab.bsky.social · 10/09/2025
Literal green chemistry #chemsky
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Auclair Lab @auclairlab.bsky.social · 04/09/2025
Doing a little setup for our new baby 👀
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Auclair Lab @auclairlab.bsky.social · 28/08/2025
The Auclair lab went tree trekking recently! Super fun teambuilding exercise.
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Auclair Lab @auclairlab.bsky.social · 20/08/2025
Very happy to meet 2020 Nobel Prize laureate @e-charpentier.bsky.social at @ircm.bsky.social!
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Auclair Lab @auclairlab.bsky.social · 13/08/2025
‼️NEW PAPER ALERT In Antimicrobial Agents and Chemotherapy, we replace an enzyme-vulnerable amide bond with a thiazole to produce potent antiplasmodial and antimalarial pantothenamide mimics. A collaboration between the Auclair lab @mcgill.ca and the Saliba lab at ANU. doi.org/10.1128/aac.... 🧵
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Auclair Lab @auclairlab.bsky.social · 11/08/2025
Balloons! #chemsky
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Auclair Lab @auclairlab.bsky.social · 07/08/2025
Finding the volume of our milling balls: if it was good enough for Archimedes, it's good enough for grad students #chemsky
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Auclair Lab @auclairlab.bsky.social · 30/07/2025
A wonderful moist-solid #chemsky
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Auclair Lab @auclairlab.bsky.social · 18/07/2025
It's gel day #chemsky
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Auclair Lab @auclairlab.bsky.social · 09/07/2025
The samples are extra colourful today #chemsky
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Auclair Lab @auclairlab.bsky.social · 03/07/2025
Throwback: in 2012, our lab investigated prodrugs - activated by the CoA pathway - to resensitize resistant bacteria to aminoglycoside antibiotics. #chemsky doi.org/10.1021/cb20...
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Auclair Lab @auclairlab.bsky.social · 21/06/2025
🚨NEW PREPRINT ALERT: In this paper, Jacob and Suzana from the Auclair lab investigate how Salmonella Typhimurium adapts to growing on itaconate, with detailed metabolic and genomic studies. Many thanks to our collaborators at McGill and Concordia! (Details below) #chemsky doi.org/10.1101/2025...
Metabolic and genomic adaptations of Salmonella Typhimurium grown on itaconate

Jacob Pierscianowski, Suzana Diaconescu-Grabari, Farhan R. Chowdhury, Andreanne Lupien, Brandon L. Findlay, Karine Auclair
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Auclair Lab @auclairlab.bsky.social · 19/06/2025
Well done to Aracelli and Alec for their great presentations! Late evening or early morning, they did wonderfully. #CSC2025 #chemsky
Aracelli standing in front of her poster.Alec giving their oral presentation.
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Auclair Lab @auclairlab.bsky.social · 10/06/2025
Worth a shot #chemsky
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Auclair Lab @auclairlab.bsky.social · 02/06/2025
Latest advances in cursed but balanced centrifuge arrangements #chemsky
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Auclair Lab @auclairlab.bsky.social · 30/05/2025
Nitrogen tank went completely empty last week... that's what two LCMS on one tank will do #chemsky
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Auclair Lab @auclairlab.bsky.social · 15/05/2025
Our very own Tarasha is a TV star now! She appeared on CBC News Montreal as part of McGill's Chemistry Outreach program, demonstrating the wonders of science to kids (and a few adults.) [We only have a video of the broadcast, but it's still worth a watch...!]
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Auclair Lab @auclairlab.bsky.social · 15/05/2025
The team took advantage of the Montreal heat wave with a picnic!
A spread of food at a picnic.
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Auclair Lab @auclairlab.bsky.social · 09/05/2025
We're not handling biohazards (at least not on this side of the lab), it's just renovation #chemsky
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Auclair Lab @auclairlab.bsky.social · 28/04/2025
The Bradford assay: born 1976, relevant forever #chemsky #biosky
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Auclair Lab @auclairlab.bsky.social · 24/04/2025
ENONE should be a valid word #chemsky
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Auclair Lab @auclairlab.bsky.social · 23/04/2025
Admin's latest in cursed but balanced centrifuge arrangements (just wait until there's an odd number...) #chemsky
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Auclair Lab @auclairlab.bsky.social · 19/04/2025
💚 #chemsky
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Auclair Lab @auclairlab.bsky.social · 14/04/2025
Recent reads from #chemsky: an air-cleaning catalyst @jljcolorado.bsky.social and regiocontrol in pyrazole alkylation @levinchem.bsky.social (among dozens of others across many fields!)
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Auclair Lab @auclairlab.bsky.social · 12/04/2025
Get rotated #chemsky
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Auclair Lab @auclairlab.bsky.social · 08/04/2025
POV: you're bacterial media #chemsky #biosky #biochemsky? (Is that the tag?)
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Auclair Lab @auclairlab.bsky.social · 02/04/2025
#chemsky
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Auclair Lab @auclairlab.bsky.social · 29/03/2025
Sooner yet...
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