I remember presenting this paper from @hunterlab.bsky.social in our journal club a year ago, when it was still on bioRxiv. I’m delighted to see it now published in Nature!
www.nature.com/articles/s41...
#Cohesion #Development #Genomicinstability #Meiosis
nature.com
Protecting double Holliday junctions ensures crossing over during meiosis - Nature
Conditional ablation experiments show that key components of the synaptonemal complex protect double Holliday junction recombination intermediates to ensure their resolution into crossover products, which are required for accurate chromosome segregation during meiosis.