On occasion I’ve been blessed to have good ideas flow through me. While there’s probably an element of luck in this, I also believe this is a deeply learnable skill, and one that many people negle...

Paul and Storm launch W00tstock 5.0 with \

Polygenic screening is a method for modifying the traits of future children via embryo selection. If that sounds like gobbledygook, then think of it a bit like choosing stats for your baby. …

The Pursuit of Emptiness by John Perry Barlow Happiness is the absence of the striving for happiness. - Chuang-Tzu (350 B.C.) Chuang-Tzu had it right. No more need be said. But such is human nature th...

We know shockingly little about one of the most important human phenomena

Excessive or persistent proinflammatory cytokine production plays a central role in autoimmune diseases. Acute activation of the sympathetic nervou...

Wilbur and Orville are circumnavigating the Ohio cornfield in their Flyer. Children from the nearby farms have run over to watch, point, and gawk. But their parents know better. An amusing toy, not…

A 200-year-old Irish classic!\r \r Lyrics:\r In the year of our lord eighteen hundred and eleven\r On March the seventeenth day\r I will raise up a beer and I'll raise up a cheer\r For Saccharomyces cerevisiae\r Here's to brewers yeast, that humblest of all beast\r Producing carbon gas reducing acetaldehyde\r But my friends that isn't all -- it makes ethyl alcohol\r That is what the yeast excretes and that's what we imbibe\r \r Anaerobic respiration*\r Also known as fermentation\r NADH oxidation\r Give me a beer\r \r [CHORUS]\r \r My intestinal wall absorbs that ethanol\r And soon it passes through my blood-brain barrier\r There's a girl in the next seat who I didn't think that sweet\r But after a few drinks I want to marry her\r I guess it's not surprising, my dopamine is rising\r And my glutamate receptors are all shot\r I'd surely be bemoaning all the extra serotonin\r But my judgement is impaired and my confidence is not\r \r Allosteric modulation\r No Long Term Potentiation\r Hastens my inebriation\r Give me a beer\r \r [CHORUS]\r \r When ethanol is in me, some shows up in my kidneys\r And inhibits vasopressin by degrees \r A decrease in aquaporins hinders water re-absorption\r And pretty soon I really have to pee\r Well my liver breaks it down so my body can rebound\r By my store of glycogen is soon depleted\r And tomorrow when I'm sober I will also be hungover\r Cause I flushed electrolytes that my nerves and muscles needed\r \r Diuretic activation\r Urination urination \r Urination dehydration\r Give me a beer\r \r [CHORUS]\r \r Happy St. Pat's\r \r *Actually, this isn't true. While both anaerobic respiration and fermentation occur without the use of oxygen, anaerobic respiration utilizes the electron transport chain to generate ATP, while fermentation does not. My bad. I would have remembered that if I wasn't trying so hard to rhyme. A new corrected version is now up on my channel: http://www.youtube.com/watch?v=L6dzUOYTQtQ\r \r CHORDS: \r \r Intro: \r D DAG / bm A\r D D A G / bm A G D\r G D A G / G D G A\r G D A bm / G D A D\r \r Pre - chorus:\r G D A bm / G D A\r \r Chorus (Li-Diddly-I):\r G D A bm A\r G D A D\r \r Verse:\r D DAG / Bm A\r D D A G / Bm A G D\r G D A G / bm A\r G D A bm / G D A D