Egg whites may be perfect for a health-conscious breakfast, but egg yolks turned out to be the key ingredient for cultivating bird embryonic stem cells (ESCs) in the lab. Using a growing medium of egg...

A common framing for governing artificial intelligence (AI) in the biological sciences is to focus on risk mitigation owing to the technology’s potential ‘dual-use’ for both beneficial and harmful applications. This is a reactive policy approach, and a broader framing that urges policymakers to actively champion the benefits alongside mitigating risks is needed, including through targeted investments aimed at securing public priorities.

Haploid embryonic stem cells for cattle and sheep are produced, opening new reproductive possibilities.

Combining expansion microscopy with super-resolution radial fluctuations captures the morphology of single proteins.

Nature Biotechnology - Biotech news from around the world

She made a name for herself as someone who understood the zeitgeist. But her successor Chloe Malle faces an uphill battle.

Norwegians go to the polls on Sunday and Monday, with domestic issues expected to be at the forefront of voters' minds.

For decades, and in the exceptional instance of the Institut Pasteur for over a century, non-profit organizations have augmented R&D to advance scientific understanding and develop affordable and ...

This study developed a highly efficient prime editing system (pvPE) based on porcine endogenous retroviral reverse transcriptase. Through extensive engineering and nocodazole treatment, pvPE achieved robust multigene editing in porcine fibroblasts, which generated Alzheimer’s disease pig models, offering a versatile platform for agricultural and biomedical applications.

The neoantigen discovery pipeline NeoDisc incorporates mass spectrometry immunopeptidomics data.

Lawyers for Dr Susan Monarez say she is being targeted for refusing "to rubber-stamp unscientific, reckless directives".

Portrait of a Lady seen in house near Buenos Aires, more than 80 years after it was looted from a Jewish art dealer in Amsterdam.

Israel has faced global condemnation for back-to-back strikes on the biggest hospital in southern Gaza this week, which killed at least 22 people, including health workers, emergency response crews a...

Nature Biotechnology - Children with rare genetic diseases get CRISPR Cures center

Engineered self-assembled RNA nanostructures (SARNs) overcome challenges in RNAi-based pest control by enhancing stability, delivery, and gene silencing efficiency. A scalable, cost-effective production framework supports the practical deployment of SARN pesticides, with applications extending to sustainable agriculture and RNA-based therapeutics.

Russia's defence ministry says more than 230 Ukrainian drones have been downed over Russia since Saturday morning.

This study addresses the challenge of recombinant alcohol dehydrogenase (ADH) aggregation in Escherichia coli, improving soluble, catalytically active yields of Rhodococcus ADH-A and ADH-G by 18.55-fold and 26.59-fold, respectively. Adaptive evolution of E. coli at high pH enhanced fitness by optimizing metabolic pathways, offering a promising approach for efficient industrial enzyme production.

An antibody–polysialic acid conjugate induces calcification on the surface of methicillin-resistant Staphylococcus aureus and boosts immunogenicity in mice.

For the past five years, CNN’s Connecting Africa has journeyed across the continent, to explore what’s driving intra-African trade, regional integration and business transformation. In this milestone ...

A new generation of wealth creators has fuelled demand for private members-only clubs in Asia's third largest economy.

The company said their leader had not set the standard and accountability they expected of employees.

This study developed the fully automated collection technology and optimum machinery (FACTORY) platform for extracellular vesicles (EVs), integrating continuous flow centrifugation and tangential flow filtration. The platform allows one-click, large-scale isolation of high-quality EVs with exceptional consistency, accelerating the clinical translation of EV-based applications.

Novel microbial species in metagenomes are identified using conserved regions within universal marker genes.

Afghanistan remains the only country in the world that prohibits girls and women from getting general education at secondary and higher levels.

Khaled Mohamed Ali El Hishri is accused of murder, torture and rape at a prison in Tripoli.

Genome stability is shaped by DNA sequence and epigenomic context, but their relative contributions to double-strand break (DSB) sensitivity remain unclear. We show that the DNA language model, GROVER...

Artificial intelligence (AI) has revolutionized life sciences, driving transformative advances in engineering clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas)-based genome editors for therapeutic and agricultural applications. Recent breakthroughs demonstrate how deep learning accelerates the discovery, engineering, and design of next-generation genome editing tools. In this review, we explore how AI-driven approaches are supercharging genome editing in three aspects: (i) structure-based methods for discovering novel genome editors neglected by conventional methods, (ii) engineering genome editors with enhanced properties, and (iii) the de novo design of entirely new genome editors endowed with bespoke functions. Finally, we discuss the current challenges and envision the future potential of data-driven AI to unlock new possibilities in genome editing, catalyzing innovations across biology and biotechnology.

Methylation changes in microbiome-derived cfRNA enable more accurate CRC diagnosis than traditional DNA or abundance-based tests.

Viral scandals have hit two actresses, a Harvard graduate and a doctor from a top Beijing hospital in recent months.

The network called it a financial decision tied to the "challenging backdrop in late night" television.