iiinova — where your digital self keeps evolving

Reposted by @ara-donia.bsky.social

Elaine Emmerson @doctoremmerson.bsky.social · 16/02/2026

Our latest preprint, led by @lizihegarty.bsky.social & aided by @erinwatson.bsky.social shows that fixation time matters when it comes to visualising #macrophages in #salivarygland & other epithelia.We find 1hr allows detection of mac subsets while preserving architecture. With @bainlab.bsky.social

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Reposted by @ara-donia.bsky.social

Mucosal Immunology @mucosalimmunol.bsky.social · 08/01/2026

Colonic macrophage heterogeneity revealed by CD11c and CD163 www.mucosalimmunology.org/article/S193...

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Reposted by @ara-donia.bsky.social

Elaine Emmerson @doctoremmerson.bsky.social · 22/09/2025

Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.

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Reposted by @ara-donia.bsky.social

Mike Dolan @dolanmjg.bsky.social · 28/04/2025

How does the brain repair myelin after injury? We mapped the full cellular choreography of white matter repair using snRNA-seq + Slide-seqv2, uncovering a type I interferon-driven glial program that recruits lymphocytes to promote remyelination. www.biorxiv.org/content/10.1... Details below 👇

biorxiv.org

Spatiotemporal Analysis of Remyelination Reveals a Concerted Interferon-Responsive Glial State That Coordinates Immune Infiltration

Remyelination, the process by which axons are re-encased in myelin after injury, is a critical step in restoring brain function, yet the dynamics from initial injury to repair remain poorly characteri...

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