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The Wistar Institute

@wistar.org
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Wistar is the nation's first independent biomedical research center. We focus on cancer, infectious disease & vaccine research to benefit human health.

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The Wistar Institute @wistar.org · 26/09/2026
Wistar scientists uncovered a surprising link between the nervous system and aggressive prostate cancer. They found the neurotransmitter NMU helps tumors evade immune attack. Blocking NMU restored anti-tumor responses in preclinical models. Learn more: bit.ly/4iMTwUk
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Wistar Scientists Identify Connection Between Nervous System and Aggressive Prostate Cancer
Wistar Scientists Identify Connection Between Nervous System and Aggressive Prostate Cancer Prostate Cancer
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The Wistar Institute @wistar.org · 23/09/2026
Wistar scientists Drs. Meenhard Herlyn & Noam Auslander are using advanced computational tools to uncover hidden patterns in melanoma tumors, helping researchers identify new pathways that could shape future treatments for patients. Learn more: bit.ly/4hkUDbf
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Wistar Scientists Advance Melanoma Research through Multidisciplinary Partnership
Wistar Scientists Advance Melanoma Research through Multidisciplinary Partnership Melanoma
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The Wistar Institute @wistar.org · 26/06/2026
Could a single injection replace weekly weight loss shots? Wistar scientists developed a single-dose DNA method that manages weight and blood glucose 10x longer than current therapies in preclinical models. Read more: bit.ly/4oL7w1C #obesity #diabetes #weightloss #biotech #Wistar
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The Wistar Institute @wistar.org · 11/06/2026
Thanks to GEN for highlighting Dr. Katherine Aird’s new @nature.com paper revealing how ovarian cancer cells use a metabolic trick to resist chemotherapy — and how blocking it could restore treatment sensitivity. 🔬 This could change the game for patients with hard-to-treat tumors. bit.ly/4x5iPpr
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The Wistar Institute @wistar.org · 03/06/2026
Stay connected to the latest discoveries at Wistar! Sign up for Wistar News to get research breakthroughs, inspiring stories, and updates on the people and projects advancing biomedical science in Philadelphia and beyond. Sign up today: www.wistar.org/news-sign-up/
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The Wistar Institute @wistar.org · 13/03/2026
Don't miss out! Join us next Wednesday, 3/18, for the Philadelphia Drug Discovery Forum! Join Mallika Singh, Ph.D., of Revolution Medicines for her talk, “Targeting the Oncogenic State of RAS.” 🕞 Doors open: 3:30 PM 🕓 Talk begins promptly: 4 PM 🥂 Networking: 5 PM 👉 Register now! bit.ly/4qQkg6B
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The Wistar Institute @wistar.org · 03/02/2026
Wistar scientists have developed a vaccine strategy that induced neutralizing antibodies with a single shot in a preclinical study—a first-ever achievement. Led by Dr. Amelia Escolano, this breakthrough could lead to simpler, faster, and cheaper vaccination protocols globally. bit.ly/4ceGGdY
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Wistar Scientists Demonstrate First-Ever Single-Shot HIV Vaccine Neutralization Success
Wistar Scientists Demonstrate First-Ever Single-Shot HIV Vaccine Neutralization Success Press Releases
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The Wistar Institute @wistar.org · 22/01/2026
Thanks to our speakers Dr. Jason DeHart and Dr. Jason Lamontagne and everyone who joined the latest Philadelphia Drug Discovery Forum! Want to connect with Philly’s biopharma community? Join the next PDDF on March 18, 4–6 p.m. Learn more: bit.ly/4bcdm7B
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The Wistar Institute @wistar.org · 16/01/2026
🚨 Last chance to register! Join us Jan 21, 4–6 p.m. at The Wistar Institute for the Philadelphia Drug Discovery Forum. Hear from leaders in biopharma and connect with peers shaping the future of medicine. Register: bit.ly/4hQgasj
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The Wistar Institute @wistar.org · 15/01/2026
Congrats to Dr. Italo Tempera on his promotion to Professor! After postdoc training in Wistar's Lieberman lab, he launched his own lab at Temple before returning to Wistar in 2020. Since then, he's published in top‑tier journals and had major grant success. 👏 Congrats! bit.ly/49mwnTv
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Italo Tempera, Ph.D.
Italo Tempera, Ph.D. Our Scientists
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The Wistar Institute @wistar.org · 12/08/2025
Hear from Federica Severi, a pre-doctoral trainee in Dr. Dan Claiborne's lab, about her work researching CAR T cells as a therapy against HIV. “What we do here is immunotherapy, where we make the immune system more powerful against infection … like HIV”
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The Wistar Institute @wistar.org · 10/06/2025
Hear from Wistar predoctoral fellow Maya Foster about what fuels her passion for science. "I work with actual cancer cells -- we do actual cancer research. Our work is quite important."
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The Wistar Institute @wistar.org · 04/06/2025
Wistar was proud to host Life Science Cares Philadelphia for a tour! As a valued partner, they support our work to expand access to life science careers for those in HS, college and beyond.
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The Wistar Institute @wistar.org · 19/05/2025
The American Society of Gene + Cell Therapy Annual Meeting was an amazing opportunity for Wistar scientists Drs. Patel, Gary and Parzych, & predoc Nick Tursi, in the lab of Dr. David Weiner, to share their important research on such a huge stage!
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The Wistar Institute @wistar.org · 02/05/2025
We’re excited to welcome Dr. Xiaoyu Zhou as assistant professor in Wistar’s Vaccine & Immunotherapy Center! Her cutting-edge work in immune cell communication & CAR T-cell engineering is a great addition to Wistar’s collaborative work advancing cancer & infectious disease therapies. bit.ly/4iLDypU
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The Wistar Institute @wistar.org · 14/04/2025
In a new collaborative paper from Wistar’s Salvino lab, the Penn Perelman School of Medicine, and the University of Leeds, published in Nature Structural & Molecular Biology, researchers have discovered a new molecular glue that combats dysregulated inflammatory signaling: bit.ly/4lf941M
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The Wistar Institute @wistar.org · 31/03/2025
Three Wistar trainees were recently recognized for excellence in science. Dr. Ignacio Rodriguez Relano received the 2024 Ching Jer Chern Postdoctoral Fellowship, while Drs. Phillip Wulfridge & Brennah Murphy Britten received the 2024 & 2025 Ching Jer Chern Memorial Awards. Congratulations!
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The Wistar Institute @wistar.org · 27/03/2025
Thanks to the Justamere Foundation for awarding Wistar’s Hubert J.P. Schoemaker Education and Training Center a 2-year, $150K grant. The grant supports Wistar’s BTT for ALL in PHL Program that helps residents of Philadelphia train for secure jobs in the region’s thriving biomedical sector.
A group of students and teachers in a training laboratory in lab coats.
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The Wistar Institute @wistar.org · 24/03/2025
On World TB Day, we shine a light on the deadliest infectious disease in the world. Caused by Mycobacterium tuberculosis, it has been around for centuries and has been tracked in the U.S. since the 1950s. Learn more about this disease and why it’s making a resurgence now: bit.ly/4iAX6ho
A microscopic image of a rod-shaped tuberculosis (TB) bacteria.
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The Wistar Institute @wistar.org · 17/03/2025
Wistar recently unveiled 2 new internal grants that will provide valuable funding opportunities to early-career researchers to foster collaborations & eventually establish independent research programs: bit.ly/4bV9zK8
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The Wistar Institute Announces Two New Internal Career Development Awards to Support Early Career Scientists
The Wistar Institute Announces Two New Internal Career Development Awards to Support Early Career Scientists Featured News
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The Wistar Institute @wistar.org · 13/03/2025
Wistar's Dr. Kristy Shuda McGuire strongly believes, “To learn science, you need to do science.” She comes from a long line of teachers & has her hand on the pulse of the latest training needed for next-gen science careers. Learn more: bit.ly/4iJaDD6
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The Wistar Institute’s Commitment to Teaching the Next Generation of Biomedical Researchers
The Wistar Institute’s Commitment to Teaching the Next Generation of Biomedical Researchers Featured News
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The Wistar Institute @wistar.org · 03/03/2025
Triple-negative breast cancer is a difficult-to-treat cancer that affects 10-15% of breast cancer patients in the U.S., defined by the absence of 3 receptors: estrogen, progesterone, and HER2. Continued cancer research is essential to overcoming this challenge. #triplenegativebreastcancerday
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The Wistar Institute @wistar.org · 28/02/2025
Wistar is pleased to announce the recruitment of its newest faculty member, Dr. Colby Maldini, to the HIV Cure and Viral Diseases Center. The Maldini lab will expand his work on CAR T cells as part of a strategy to cure HIV and other viral threats. bit.ly/4gWzcv2
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The Wistar Institute Announces Recruitment of First Caspar Wistar Fellow to Join HIV Cure and Viral Diseases Center
The Wistar Institute Announces Recruitment of First Caspar Wistar Fellow to Join HIV Cure and Viral Diseases Center Press Releases
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The Wistar Institute @wistar.org · 28/02/2025
New preclinical research from Wistar’s @filippov81.bsky.social published in Cancer Discovery shows how brain cancer reprograms immune cells to work for the cancer rather than against it. Their discovery also enables a potential treatment to disrupt the reprogramming process. bit.ly/4ijBIMT
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The Wistar Institute Discovers a Promising Target in Brain Cancer
The Wistar Institute Discovers a Promising Target in Brain Cancer Press Releases
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The Wistar Institute @wistar.org · 28/02/2025
The Wistar Institute's Montaner lab was pleased to host members of the HIV Advocacy for Cure Academy, who received a tour of the Institute and Dr. Montaner's laboratory facilities where scientists continue their work to seek a cure for HIV.
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The Wistar Institute @wistar.org · 27/02/2025
Some questions Wistar's EHS head Roma Maraj-Owens thinks about a lot: “What are your experimental procedures? How can we protect our employees and the environment?” Read more about how she ensures institutional safety in her Q&A: bit.ly/41lh0FP
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Roma Maraj-Owen Makes Sure Wistar Lab Health & Safety is Her Top Priority
Roma Maraj-Owen Makes Sure Wistar Lab Health & Safety is Her Top Priority Featured News
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The Wistar Institute @wistar.org · 17/02/2025
In their second “Top Read” paper in less than a year, Wistar’s Montaner lab has published the successful preclinical results of their new anti-HIV approach: NuKES, or Natural Killer Enhancement Strategy, which targets the viral reservoirs standing in the way of a cure. bit.ly/4hF0UNZ
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Scientists at The Wistar Institute’s HIV Cure and Viral Diseases Center Develop New Natural Killer Cell Strategy to Target HIV
Scientists at The Wistar Institute’s HIV Cure and Viral Diseases Center Develop New Natural Killer Cell Strategy to Target HIV Press Releases
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The Wistar Institute @wistar.org · 12/02/2025
Many thanks to @jenheemstra.bsky.social of Washington University in St. Louis for joining The Wistar Institute as part of the Distinguished Lectures in Cancer Research series, to speak to the importance of intentional, high-quality mentorship in the sciences. Read more: bit.ly/41ao9d3
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The Wistar Institute @wistar.org · 05/02/2025
In a new paper, Wistar’s Villanueva lab has discovered a new strategy to treat melanomas harboring mutations in the NRAS gene that don’t respond to MAPK inhibitors. Their treatment kills these mutant melanoma cells in preclinical testing with FDA-approved drugs. Our story: bit.ly/411yfwB
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The Wistar Institute Scientists Discover New Weapon to Fight Treatment-Resistant Melanoma
The Wistar Institute Scientists Discover New Weapon to Fight Treatment-Resistant Melanoma Press Releases
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The Wistar Institute @wistar.org · 05/02/2025
Wistar is hiring! Friday 2/7, join us at Temple University's job fair from 11-2 pm at the Howard Gittis Student Center to learn about our openings for postdoctoral fellowships and research assistant roles throughout more than 30 labs. Hope to see you there! No registration required.
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The Wistar Institute @wistar.org · 04/02/2025
Thanks to a new research grant from the Melanoma Research Foundation, The Wistar Institute’s Dr. Kazuko Nishikura is embarking on a project she hopes will serve as a proof of concept for a cancer treatment decades in the making. Our story: bit.ly/3WKOtYs
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The Wistar Institute’s Dr. Kazuko Nishikura Launches Preclinical Testing of New Melanoma Immunotherapy
The Wistar Institute’s Dr. Kazuko Nishikura Launches Preclinical Testing of New Melanoma Immunotherapy Featured News
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The Wistar Institute @wistar.org · 03/02/2025
Every cancer case starts somewhere, While new treatments are vital, prevention is just as key to protecting health. That’s why researchers at Wistar’s Ellen and Ronald Caplan Cancer Center pursue research to detect risks early & stop cancer in its tracks. #nationalcancerpreventionmonth
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The Wistar Institute @wistar.org · 30/01/2025
Education and Training Center is expanding our job-training programs for PA science careers with a new Quality Science Pathway Apprenticeship Program and further investment in existing programs. Read more: bit.ly/4jD3Fkb
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The Wistar Institute Receives $600,000 Grant to Expand Apprenticeship Programs in its Hubert J.P. Schoemaker Education and Training Center
The Wistar Institute Receives $600,000 Grant to Expand Apprenticeship Programs in its Hubert J.P. Schoemaker Education and Training Center Press Releases
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The Wistar Institute @wistar.org · 29/01/2025
Wistar welcomed the Greater Philadelphia Chapter of the Association of Fundraising Professionals for its 2025 Annual Meeting. Members heard the association’s vision for the upcoming year and took time to network & discuss best practices in donor stewardship.
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The Wistar Institute @wistar.org · 27/01/2025
Philadelphia has one of the most punctual airports in the world, so it's easy to travel to and from The Wistar Institute. Whether you’re heading to a conference, a collaboration, or returning from a visit back home, you’ll get to your destination on time. #WorkAtWistar
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The Wistar Institute @wistar.org · 21/01/2025
In collaboration, The Wistar Institute and Stanford University researchers report results from a first-in-human clinical trial testing a novel investigational drug for cancers associated with the ubiquitous Epstein-Barr Virus (EBV). Our story: bit.ly/3WsbxLC
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Scientists at The Wistar Institute and Stanford University Report Encouraging Results on First-in-Human Clinical Trial for an Investigational Drug to Treat Epstein-Barr Virus Cancer
Scientists at The Wistar Institute and Stanford University Report Encouraging Results on First-in-Human Clinical Trial for an Investigational Drug to Treat Epstein-Barr Virus Cancer Press Releases
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The Wistar Institute @wistar.org · 17/01/2025
Congratulations to Wistar Executive Vice President Luis Montaner, whom @immunologyaai.bsky.social has recognized with their highest honor of Distinguished Fellow. The 2025 Fellows are honored for "outstanding scientific contributions as well as their service to... the immunology community."
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The Wistar Institute @wistar.org · 08/01/2025
Wistar’s collaborations with Penn, Philadelphia College of Osteopathic Medicine, and University of Bologna allow PhD students to pursue research at Wistar, where leading experts train, guide, and mentor students on their research-career journeys. bit.ly/41ZpEeV #nationalmentoringmonth
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The Wistar Institute @wistar.org · 03/01/2025
This #NationalTriviaDay, test yourself against The Wistar Institute Trainee Association in a round of trivia, with topics covering everything from The Wistar Institute to biology to the great city of Philadelphia: bit.ly/3BUsneY #trivia
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The Wistar Institute @wistar.org · 20/12/2024
The Wistar Institute has been named one of the world’s top 1000 companies in a new ranking from @newsweek.com’s Excellence Index 2025, which recognized Wistar for “leading the way” in its sector. Wistar ranked first among Pennsylvanian companies. bit.ly/3VRIosV
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Newsweek Magazine in Collaboration with Best Practice Institute Recognizes The Wistar Institute in 2025 ‘Excellence Index’
Newsweek Magazine in Collaboration with Best Practice Institute Recognizes The Wistar Institute in 2025 ‘Excellence Index’ Press Releases
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The Wistar Institute @wistar.org · 19/12/2024
@councilmemberjg.bsky.social visited Wistar, toured the Montaner #HIV research lab, & discussed our education & training programs that are committed to building a Philadelphia workforce for science careers needed now. #STEMcareertraining #STEMapprenticeships
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The Wistar Institute @wistar.org · 17/12/2024
We sat down with Dr. Dan Claiborne to learn more about how his research in CAR T cells will support the emboldened HIV research mission at Wistar through the new HIV Cure and Viral Diseases Center. Read our story here: bit.ly/3VLOtab
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How The Wistar Institute’s Dr. Dan Claiborne Engineers CAR T Cells to Fight HIV
How The Wistar Institute’s Dr. Dan Claiborne Engineers CAR T Cells to Fight HIV Featured News
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The Wistar Institute @wistar.org · 11/12/2024
Thanks to support from The V Foundation, Drs. Nan Zhang and Noam Auslander have been named as V Scholars and awarded $1.2 million in grant funding to support research that aims to improve existing cancer therapies. Our story: bit.ly/4gudEpE
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The Wistar Institute Receives Two Biomedical Research Grants from the V Foundation for Cancer Research
The Wistar Institute Receives Two Biomedical Research Grants from the V Foundation for Cancer Research Press Releases
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The Wistar Institute @wistar.org · 06/12/2024
Wistar in the news: thanks to Inside Precision Medicine for their story on the latest research from The Wistar Institute's Weiner lab, the first-ever trispecific T cell engager for treating glioblastoma. The approach significantly enhanced survival in preclinical testing. bit.ly/3BsLBbj
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The Wistar Institute @wistar.org · 06/12/2024
Wistar’s Communications & Marketing Team was honored with a Pepperpot Award for its external newsletter, The Wistar News. The award, started in 1968 to recognize excellence in communications & public relations, is named after a beloved Philly Campbell’s soup. www.wistar.org/news-sign-up/
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The Wistar Institute @wistar.org · 05/12/2024
Wistar’s Dr. Rahul Shinde studies new potential therapies for treatment resistant cancers like pancreatic cancer. Learn more about his lab’s work, and how diet and the gut microbiome may affect cancer risk, in the latest edition of Wistar Science Update: bit.ly/3CYohTb
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The Wistar Institute @wistar.org · 03/12/2024
New research: Scientists at The Wistar Institute’s Vaccine & Immunotherapy Center, led by EVP Dr. David Weiner, have designed and tested a novel immunotherapy for glioblastoma that counters the cancer’s treatment resistance and increases survival in preclinical lab testing. bit.ly/3CTrW4G
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Wistar Institute Researchers Design Novel Immunotherapy for Brain Cancer
Wistar Institute Researchers Design Novel Immunotherapy for Brain Cancer Press Releases
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