Jesus Angulo @angulo-lab.bsky.social · 20/04/2026Last Saturday we had a tasting of the real life "ss-NMR" protocol: "Sherry-Saturday: No More Research". 🍷🍷 Jerez de la Frontera (Spain) 041
Jesus Angulo @angulo-lab.bsky.social · 19/11/2025The III Workshop of the MSCA-DN GlyCanDrug started in Seville at cicCartuja @csic.es on 18.11.2025. Four days of glycoscience and cancer, as well as top soft skill courses for the 10 PhD students of the network. 021
Reposted by Jesus AnguloCarolyn Bertozzi @carolynbertozzi.bskyverified.social · 31/10/2025Science brings us new miracles every day. Update from a mother whose son was the first patient dosed with Grace Science's gene therapy for NGly1 deficiency (GS-100). Video can be seen on YouTube. #glycotime www.youtube.com/watch?v=tdNn...youtube.com 25113
Jesus Angulo @angulo-lab.bsky.social · 24/10/2025Really excited about this work! We hope Fast NMR scoring can contribute to drug discovery. Thanks Dusan Uhrin @edinburghchem.bsky.social and Ridvan Nepravishta @rnepravishta.bsky.social @crhorizons.bsky.social for getting us on board of this collaboration. @csic.es pubs.acs.org/doi/10.1021/...pubs.acs.orgFast and Reliable NMR-Based Fragment Scoring for Drug DiscoveryFragment-Based Drug Discovery (FBDD) is a powerful strategy used in the development of new therapeutics. Molecular fragments are screened against a target protein, where interactions are typically cha... 083
Jesus Angulo @angulo-lab.bsky.social · 06/09/2025Big congrats to Jona for his successful defence of his PhD Thesis. Thanks to the panel @albasilipo.bsky.social Paco Corzana, Pedro Nieto, Victoria Gómez and Miguel A. Rodríguez Carvajal. Great NMR cake for the celebration!!! @csic.es 072
Jesus Angulo @angulo-lab.bsky.social · 02/09/2025A heads-up: Friday 5th 11am, first PhD defence in the @angulo-lab.bsky.social since the lab move to Seville. It'll be at cicCartuja @csic.es. Jona's presenting his work on some pretty cool new STD NMR approaches for low-affinity biomolecular interactions. Co-supervised with Juan C. Muñoz-García. 072
Reposted by Jesus AnguloCIC bioGUNE @cicbiogune.bsky.social · 24/07/2025#bioGUNE_Talent | 👏 Óscar Millet #CICbioGUNE @brtaeus.bsky.social, appointed Vice President of @group-ampere.bsky.social, Europe’s top #NMR organization, the first Spanish scientist to hold this role 🎉 Congratulations, Óscar! 🔗 ow.ly/hxi450Wuwiw 0116
Jesus Angulo @angulo-lab.bsky.social · 04/07/2025Great week of science in Bilbao @ XL Meeting of the Spanish Royal Society of Chemistry @rseq-quimica.bsky.social. I really enjoyed presenting our developments in Epitope-Perturbation-by-Mutation STD NMR spectroscopy in my invited talk. It opened great discussions with fantastic colleagues. @csic.es 071
Jesus Angulo @angulo-lab.bsky.social · 01/06/2025On our way to Jaca #NMRschool #ManuelRicoNMR #NMR2025 051
Jesus Angulo @angulo-lab.bsky.social · 05/05/2025Starting our mid-term meeting @GlyCanDrug at @i3S_UPorto in Porto. Putting together the glycoscience we're developing in our European Doctoral Network 031
Reposted by Jesus AnguloGlyco@Alps @glyco-alps.bsky.social · 12/03/2025Registration to our "Structural Glycoscience" Summer School is open !! Come to Grenoble for #glycotime lectures, practicals, visit to @esrf.fr @cermav.bsky.social and IBS. Information and registration at glycoalps.univ-grenoble-alpes.fr/news/summer-... 01311
Reposted by Jesus AnguloAnne Imberty @anneimb.bsky.social · 12/03/2025Our famous "Structural Glycoscience" summer school is back in June 2025 in Grenoble !! with @angulo-lab.bsky.social @elisafadda.bsky.social @glycoexpasy.bsky.social @romain-vives.bsky.social and many others. Attendance is limited to 40 so register quickly ! 0115
Jesus Angulo @angulo-lab.bsky.social · 05/03/2025Our first paper on STD NMR Epitope Perturbation by Mutation: Unveiling Mechanism of YM155 as an Arginine-Glycosyltransferases Inhibitor Effective in Treating Enteropathogenic Diseases pubs.acs.org/doi/10.1021/... Great collabor. Ramón Hurtado, Weston Struwe, Valeria Calvaresi, and Philip Hardwidgepubs.acs.orgSTD NMR Epitope Perturbation by Mutation Unveils the Mechanism of YM155 as an Arginine-Glycosyltransferases Inhibitor Effective in Treating Enteropathogenic DiseasesEnteropathogenic arginine-glycosyltransferases (Arg-GTs) alter higher eukaryotic proteins by attaching a GlcNAc residue to arginine acceptor sites, disrupting essential pathways such as NF-κB signalin... 052
Jesus Angulo @angulo-lab.bsky.social · 22/01/2025A privilege to have my former boss Thomas Peters visit our research group in Seville @csic.es, as an invited speaker at the III @GlycoNoVi Workshop. 031
Jesus Angulo @angulo-lab.bsky.social · 20/01/2025Excellent scientific discussions today!! III workshop of the "GlycoNoVi" MSCA-DN European Network in Seville. We thank cicCartuja @csic.es for kindly hosting our meeting at the research centre. (#MSCA-DN) 053
Reposted by Jesus AnguloLara K. Mahal @glycocode.bsky.social · 13/01/2025Proud of @faezehjame.bsky.social and our latest paper on upregulation by #miRNA. miRNA upregulate protein expression of CD98hc, ST3GAL1 and ST3GAL2 in a coordinated manner. Regulation is bidirectional, changing the picture on how these #RNA work. #glycotime www.science.org/doi/10.1126/... 🧪science.orgScreening the human miRNA interactome reveals coordinated up-regulation in melanoma, adding bidirectional regulation to miRNA networksAnalysis of ST3GAL1/2 and CD98hc regulation by miRNA reveals co–up-regulation, adding a bidirectional twist to miRNA networks. 55311
Jesus Angulo @angulo-lab.bsky.social · 10/01/2025Today, we officially welcome Pablo Valverde to the group, working on our @csic.es MOMENTUM project. Starting gun fired for exciting computational+NMR times to characterise challenging weak protein-ligand interactions. 092
Reposted by Jesus AnguloDerek Lowe @dereklowe.bsky.social · 03/01/2025RIP J. Fraser Stoddart and Martin Karplus.science.orgTwo More Great Names Pass 17926
Jesus Angulo @angulo-lab.bsky.social · 12/12/2024Attention recent PhD's (thesis finished in 2023 or 2024): the ‘Juan de la Cierva’ call is opening. 2 year postdoc contract! Interested in molecular recognition for development of new drugs (NMR spectroscopy, computation, AI, biophysical techniques)? Contact us! www.aei.gob.es/convocatoria...aei.gob.esAyudas para contratos Juan de la Cierva 2024 | Agencia Estatal de InvestigaciónBuscarLas ayudas Juan de la Cierva tienen como finalidad fomentar la incorporación de jóvenes, en posesión del grado de doctor, con objeto de que completen su formación investigadora postdoctoral en centros de I+D españoles. 031
Reposted by Jesus AnguloElisa Fadda @elisafadda.bsky.social · 04/12/2024Fancy glycan of the week 🍬: here ⬇️ is THE fanciest tetrantennary+SDa antigen bisected N-glycan I have ever seen! Found in bovine pregnancy-associated glycoproteins (PAGs) during midpregnancy, see doi.org/10.1093/glyc... This (and its core-fucosylated companion) will be soon on glycoshape.org 😀👍 1143
Reposted by Jesus AnguloMartina Delbianco @delbiancom.bsky.social · 04/12/2024#PhDposition available in my group at the @mpici.bsky.social! Join us to develop new #carbohydratematerials #chemistryjobs #researchjobs #glycotime jobs.mpikg.mpg.de/jobposting/a...jobs.mpikg.mpg.dePhD position to develop synthetic carbohydrate materials 058
Reposted by Jesus AnguloAlexander Titz @titzlab.bsky.social · 04/12/2024I am very proud to share a long story on lectins and biofilm imaging just published in JACS Au by Eva and Lisa in cooperation with many colleagues such as @anneimb.bsky.social 😍 #glycotime #chembio #AMR please have a look here: pubs.acs.org/doi/10.1021/...pubs.acs.orgHigh-Affinity Lectin Ligands Enable the Detection of Pathogenic Pseudomonas aeruginosa Biofilms: Implications for Diagnostics and TherapyPseudomonas aeruginosa is a critical priority pathogen and causes life-threatening acute and biofilm-associated chronic infections. The choice of suitable treatment for complicated infections requires... 0297
Reposted by Jesus AnguloAnne Imberty @anneimb.bsky.social · 04/12/2024This was an amazing collaboration with high affinity ligand for Pseudomonas aeruginosa lectins able to target the bacteria in mice !! #glycotime 🍾 0136
Reposted by Jesus AnguloGaston Courtade @gcourtade.bsky.social · 04/12/2024Perspective by Higman et al: deposition of data for titrations, relaxation rates, PREs, etc in a standardized way, e.g. the NEF format could help develop AI models to accurately predict the dynamic behaviour of a protein from the primary sequence alone. #NMRchat doi.org/10.1007/s108...doi.orgPerspective: on the importance of extensive, high-quality and reliable deposition of biomolecular NMR data in the age of artificial intelligence - Journal of Biomolecular NMRArtificial intelligence (AI) models are revolutionising scientific data analysis but are reliant on large training data sets. While artificial training data can be used in the context of NMR processin... 0189
Reposted by Jesus AnguloRalph Adams @ralphwadams.bsky.social · 01/12/2024🎄 Exciting News for NMR Enthusiasts! 🎄 This December, join us for an NMR Advent Calendar! 🧪📅 New challenge unlocked on our website each day. 🔓 Starts Today - 1st of December 💻 Visit: nmr.chemistry.manchester.ac.uk/advent24 🎁 Test your knowledge, learn, and have fun! #NMRchat #AdventCalendarnmr.chemistry.manchester.ac.uk 095
Jesus Angulo @angulo-lab.bsky.social · 01/12/2024Sunday coffee time dilation... What a beautiful view!! 😍 030
Reposted by Jesus AnguloMagnetic Resonance News @nmr900.bsky.social · 28/11/2024Postdoctoral Position at the University of Gothenburg (Sweden) – Developing AI tools for Biomolecular NMR and Structural Biology, posted 11/26/2024 listes.services.cnrs.fr/wws/arc/nmr/... #NMRjobs #NMRchat #NMR 🧲listes.services.cnrs.fr nmr - Magnetic Resonance Mailing List - confirm_action 022
Reposted by Jesus AnguloM. Eugenio Vazquez @glowsticks.bsky.social · 28/11/2024If you have the right profile 💻, you should seriously consider this offer as a once-in-a-lifetime opportunity. Manuel is not only an exceptional scientist, but also—and this is crucial for potential students and postdocs—a kind person who cares about his people. 163
Reposted by Jesus AnguloCarolyn Bertozzi @carolynbertozzi.bskyverified.social · 27/11/2024X has copied the starter pack concept 😂 1623216
Reposted by Jesus AnguloFabien Ferrage @fabferrage.bsky.social · 11/11/2024I am happy to share the preprint of a review coordinated by my colleague Giacomo Parigi on relaxometry of biomolecules systems. doi.org/10.26434/che...doi.orgField-dependent relaxation profiles of biomolecular systemsThe function of biomolecular systems, including biological macromolecules, often crucially depends on their dynamics. Nuclear Magnetic Resonance (NMR) is one of the most informative methods used to st... 1136
Reposted by Jesus AnguloAnne Imberty @anneimb.bsky.social · 19/11/2024Awesome webinar by @elisafadda.bsky.social at GlyGen. series. Everything you should know for building the GLYCO of your glycoproteins with GlycoShape (glycoshape.org) 1143
Jesus Angulo @angulo-lab.bsky.social · 22/11/2024Proud of Henry Flatau, PhD student of our group after being awarded the Prize for Best Oral Presentation at the PhD Students Congress at the Chemistry Faculty of the University of Seville. NMR spectroscopy, computational chemistry & (bio)molecular interactions. 291
Jesus Angulo @angulo-lab.bsky.social · 21/11/2024It was a great privilege to chair the ChemBio VII conference (www.chembiovii.es) held in Seville. The organizing committee worked very hard to make the meeting a success. Amazing contributions and discussions in Chemical Biology with colleagues, with the beautiful Seville as a backdrop. 2134
Reposted by Jesus AnguloMax Planck Institute of Colloids & Interfaces (MPICI) @mpici.bsky.social · 21/11/2024Congrats to @delbiancom.bsky.social for winning the "European Award for Young Research Leaders of the Spanish Specialized Group of #ChemicalBiology"! Read how she designs synthetic #glycans to explore their untapped potential for #MaterialsScience ➡️https://tinyurl.com/4nxd5s6b #skychem 1122
Reposted by Jesus AnguloProf. Zoë Waller @drzoewaller.bsky.social · 20/11/2024Grateful for the opportunity to be able to present and discuss our work at ChemBio VII in Seville. Thank you to Jesus Angulo for the kind invitation- and also for taking this photo! 2222
Reposted by Jesus AnguloElisa Fadda @elisafadda.bsky.social · 18/11/2024If you are interested or working in #structuralbiology, as you see any protein (yes, *any*), you should be thinking: is it glycosylated? The answer is likely to be yes! You can predict N-glycosylation sites and rebuild all types of glycans with ReGlyco glycoshape.org 😌 Check out the example ⬇️ 1/2 415137
Jesus Angulo @angulo-lab.bsky.social · 17/11/2024White and red "matured grape juice" to celebrate meeting, after many years, former members of the lab Serena Monaco and Ridvan Nepravishta in Seville. Happy to see them doing, and looking, so well! www.chembiovii.es/CHEMBIOVII2024 072
Jesus Angulo @angulo-lab.bsky.social · 15/11/2024The Angulo lab working hard to have everything ready and in place for the ChemBio VII Meeting this Monday in Seville (www.chembiovii.es/CHEMBIOVII2024 ) 163
Reposted by Jesus AnguloJon Agirre @glycojones.bsky.social · 14/11/2024Here is a great opportunity to join YSBL (York) and work with @mjplevin.bsky.social and myself! www.findaphd.com/phds/project...findaphd.comApplication of Deep Learning (AI) to the refinement of XH-π interactions in protein atomic structure determination at University of York on FindAPhD.comPhD Project - Application of Deep Learning (AI) to the refinement of XH-π interactions in protein atomic structure determination at University of York, listed on FindAPhD.com 035
Reposted by Jesus AnguloMarcin Czerwinski @czerwinsmarcin.bsky.social · 13/11/2024Interesting piece about glycosylated RNAs (glycoRNAs): sialylated glycoRNAs are present in human cell lines, and sialylation of glycoRNAs depends on the catalytic isoforms of the oligosaccharyltransferase (OST) complex. tinyurl.com/vhz2rj8atinyurl.comProcessing of N-glycans in the ER and Golgi influences the production of surface sialylated glycoRNA - Glycoconjugate JournalGlycoconjugates, including glycans on proteins and lipids, have obtained significant attention due to their critical roles in both intracellular and intercellular biological functions and processes. N... 073
Reposted by Jesus AnguloElisa Fadda @elisafadda.bsky.social · 13/11/2024Here below is a slide summarising all that you can do with glycoshape today! And so much more to come soon! Any questions/feedback please let us know! 2/2 2123
Reposted by Jesus AnguloElisa Fadda @elisafadda.bsky.social · 13/11/2024As we (my lab and I) are new here 😻, let me introduce some exciting #glycotime work we recently published in Nature Methods doi.org/10.1038/s415... GlycoShape is a completely OA database and toolbox to restore the 3D structure of glycans on glycoproteins 🥳 You can find it at glycoshape.org 1/2 510922
Reposted by Jesus AnguloMax Planck Institute of Colloids & Interfaces (MPICI) @mpici.bsky.social · 12/11/2024The Society for #Glycobiology has awarded its Distinguished Service #Award to the editors of "Essentials of Glycobiology", including our Director, Peter Seeberger. ➡️ academic.oup.com/glycob/artic... (end of page) #glycotime 0229
Jesus Angulo @angulo-lab.bsky.social · 12/11/2024Hello everyone!! New in this BlueSky... I share with you our study on the IT-sialidase from R. gnavus RgNanH-GH33. Brilliant collaboration with Nathalie Juge (Quadram Institute, Norwich), and all the work led by Serena Monaco (UEA, Norwich). www.sciencedirect.com/science/arti...sciencedirect.comMultifrequency-STD NMR unveils the first Michaelis complex of an intramolecular trans-sialidase from Ruminococcus gnavusRgNanH is an intramolecular trans-sialidase expressed by the human gut symbiont Ruminococcus gnavus, to utilise intestinal sialylated mucin glycan epi… 193