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Angel Pizarro

@angelp.bsky.social
788 followers 840 following 380 posts

Product Architect in the NVIDIA Digital Bio team, once again a bioinformatics guy. Also a fussy coffee guy.

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Angel Pizarro @angelp.bsky.social · 29/09/2026
Ugly start
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Angel Pizarro @angelp.bsky.social · 21/09/2026
Resident Evil may be my favorite movie of the year.
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Angel Pizarro @angelp.bsky.social · 01/09/2026
Yep
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Angel Pizarro @angelp.bsky.social · 29/08/2026
Just over 300 miles ridden on it so far. Super fun.
Picture of a Maeving black electric motorcycle. 🏍️
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Angel Pizarro @angelp.bsky.social · 28/08/2026
Happy Tan Suit Day to all who celebrate
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Angel Pizarro @angelp.bsky.social · 26/08/2026
Fak, too many of the good ones leaving us.
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Angel Pizarro @angelp.bsky.social · 20/08/2026
In that sweet spot where you are working on so many projects that you get nothing done on any of them.
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Brendan Bouffler ('boof') @boofla.bsky.social · 07/08/2026
youtu.be/eW0kK4PUKdY
youtu.be
Scientific software can feel like a hazing ritual. Spack solved that.
YouTube video by Discovered by Compute
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Adam Phillippy @aphillippy.bsky.social · 06/08/2026
For the past 30 years, “whole-genome sequencing” has been a misnomer. Today the T2T Consortium publishes a dozen papers heralding a future of truly complete genomes for humans and nearly any vertebrate 👨‍🔬🐒🐦🐀🦒🐎🫏🐹🐟 (sorry, no salamanders): www.cell.com/consortium/t... 🧵[1/15]
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Angel Pizarro @angelp.bsky.social · 23/07/2026
Nice quality of life improvement - Parabricks migrated their docs system to Fern so that it can better serve agents with a built-in MCP server. Check out the site and get a few ways to register it in your harness:
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Angel Pizarro @angelp.bsky.social · 21/07/2026
I was having a conversation the other day about car insurance. In short they were using one of those trackers to lower their insurance rate… I am vehemently opposed to it. Insurance is for catastrophes and you do NOT want to be dealing with corp lawyers during the aftermath. Full tort is the way.
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Reposted by Angel Pizarro
Nextflow @nextflow.io · 14/07/2026
A little-known feature of Nextflow is that it can support iterative processes - feeding process outputs back as inputs until a threshold is met. This is especially useful for ML training, molecular dynamics simulations, and other looped workflows. 📚 Find out more: hubs.la/Q04prlGh0
hubs.la
Running Until: Iterative Loops in Nextflow | Seqera
Nextflow can express iterative loops with a topic channel and an until check. Here's how to make a process feed on its own output, no recursion needed.
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Angel Pizarro @angelp.bsky.social · 13/07/2026
In DC for the ISMB conference this week. Have't been here is a while and it's nice to be back walking around familiar spaces.
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Angel Pizarro @angelp.bsky.social · 02/07/2026
Current status
Picture of legs by a pool
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Angel Pizarro @angelp.bsky.social · 30/06/2026
For a conference of technical people, the ISMB website is .... really something
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Angel Pizarro @angelp.bsky.social · 30/06/2026
I think DJT is right that the average voter doesn’t care about the housing bill. It’s abstract and they wouldn’t see results until years from now (if ever). Fox is not covering it so they may not even know it exists. They only cover DJT “pressuring congress” to pass the SAVE act.
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Angel Pizarro @angelp.bsky.social · 30/06/2026
Great editorial use of AI as an assistive technology. Doesn’t outsource your voice/science/skills
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Angel Pizarro @angelp.bsky.social · 19/06/2026
Yep
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Stephen Turner @stephenturner.us · 18/06/2026
10 tips for getting better R code from your AI coding agent www.infoworld.com/article/4184... #Rstats
infoworld.com
10 tips for getting better R code from your AI coding agent
With the proper setup and guidance, you can have Claude Code, Codex, Posit Assistant, and other coding agents writing R code like a pro. Here’s how.
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Angel Pizarro @angelp.bsky.social · 16/06/2026
Stroke rate a good indicator he won’t last the full term. What happens after that is anybody’s guess.
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Angel Pizarro @angelp.bsky.social · 14/06/2026
I am of the opinion that a Rust rewrite should NOT have to have “Rust” or “rs” in the name, just bump the major version number. Glad to see Rob did so with salmon.
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Rob Patro @robp.bsky.social · 14/06/2026
salmon 2.0 (the rust re-write) is now live! It's also the version you get if you install via bioconda. This is a from-scratch rewrite in rust, and the base for future development. I'll post a more detailed thread tomorrow, but you can read the docs here combine-lab.github.io/salmon/
combine-lab.github.io
salmon
Fast, accurate transcript quantification from RNA-seq reads.
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Angel Pizarro @angelp.bsky.social · 14/06/2026
After looking at a Maeving for 4 years I decided it’s now or never. Took delivery of this awesome piece of kit a couple of days ago.
Maeving RMS1 Blackout electric motorcycle. Me sitting on the motorcycle
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Clara Jeffery @clarajeffery.bsky.social · 08/06/2026
1/ What if you put all the ways that Jared Kushner is selling out America while lining his pockets into one place? In our new cover story, @cjcmichel.bsky.social did just that www.motherjones.com/politics/202...
Cover of Mother Jones, featuring a baby Jared Kushner swimming after a dollar with the headline Nevermind the Corruption: How nepo baby Jared Kushner is selling America out.
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Angel Pizarro @angelp.bsky.social · 28/05/2026
Yep
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Angel Pizarro @angelp.bsky.social · 18/05/2026
Off to BioIT in Boston this week. Mainly to catch up with as many biotech folks as I can so we can figure out a way through this AI transformation together.
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Angel Pizarro @angelp.bsky.social · 29/04/2026
current status
Selfie in front computer monitor showing the NVIDIA logo, which is where I work now.
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Angel Pizarro @angelp.bsky.social · 25/04/2026
Thought of the day - striving to be the better person (taking the high road, turn the other cheek, etc) is hard sometimes. Sometimes you want to be petty but you know it’s not good for you in the long term so you hold back. Honestly I don’t know what is better but that’s how I operate
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Angel Pizarro @angelp.bsky.social · 23/04/2026
Wrote a quick blog on LinkedIn about some thoughts I've been having. www.linkedin.com/pulse/some-t...
linkedin.com
Some thoughts on bioinformatics and AI Agents
Over the years, the bioinformatics community has adopted software engineering best practices to bring order to the chaos of self-taught programming. We embraced concepts like DRY (Don’t Repeat Yoursel...
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Reposted by Angel Pizarro
Stephen Turner @stephenturner.us · 14/04/2026
2 years ago I went to bed feeling great, woke up next morning with a painful ear and hearing loss (which became permanent). Because of a shingles infection in my auditory nerve. Get the vaccine if you're eligible www.wired.com/story/shingl...
wired.com
You Should Be More Freaked Out by Shingles
The viral infection leaves millions with chronic pain, increased stroke risk, and lifelong nerve damage—yet vaccination rates remain dangerously low.
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Angel Pizarro @angelp.bsky.social · 05/04/2026
I decided that this year I will be going back to my bioinformatics roots and working on ML in life sciences. I’ve been one step removed from the fray for a little over 5 years so it’ll be interesting to dive back in and see what’s what.
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Angel Pizarro @angelp.bsky.social · 05/04/2026
Nice thread summing up what everyone is going through right now.
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Angel Pizarro @angelp.bsky.social · 04/04/2026
Springtime Funtime
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Angel Pizarro @angelp.bsky.social · 01/04/2026
Testing out Gemini for coding up a native macOS app for tracking espresso profiles, beans, etc. Should be interesting. Need a name for it though. Current front runners are “Grounds Control” and “Brew Base”. Suggestions welcome.
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Angel Pizarro @angelp.bsky.social · 31/03/2026
Another pic because this tree is awesome.
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Angel Pizarro @angelp.bsky.social · 31/03/2026
Annual weeping cherry bloom
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Angel Pizarro @angelp.bsky.social · 30/03/2026
Project Hail Mary was a really great movie adaptation from the book. I agreed with a lot of what they needed to edit out for time, but it did lose some of the deeper character development as a result.
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Angel Pizarro @angelp.bsky.social · 29/03/2026
Yep.
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Angel Pizarro @angelp.bsky.social · 29/03/2026
Loooooool
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Angel Pizarro @angelp.bsky.social · 23/03/2026
😍
Picture of my espresso counter setup containing a big manual grinder, the Meticulous espresso machine, and several accessories.
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Angel Pizarro @angelp.bsky.social · 23/03/2026
In these trying times, you gotta celebrate small enjoyments where you can: 1. I painted my home office, put up all the prints and decorations I have wanted to do since moving in two years ago. Added a hammock for thinking deep thoughts. 2. New espresso machine is on the delivery truck! So excited.
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Angel Pizarro @angelp.bsky.social · 23/03/2026
TACO Monday
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Angel Pizarro @angelp.bsky.social · 14/03/2026
Painting crown molding sucks. That is all.
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Angel Pizarro @angelp.bsky.social · 09/03/2026
Tired of winning
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Boze Herrington, Library Owl @sketchesbyboze.bsky.social · 08/03/2026
I get yelled at for saying this but for many hundreds of years people went to university not to get diplomas or be employable but because immersion in the humanities was considered foundational to a good life, and school must return to its original purpose: the joy of learning.
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Angel Pizarro @angelp.bsky.social · 08/03/2026
VIX going to go to 50 this week
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Kevin Gannon (now a Moo Deng fan account) @thetattooedprof.bsky.social · 08/03/2026
we have saved daylight but at what cost
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Kendra "Gloom is My Beat" Pierre-Louis @kendrawrites.com · 08/03/2026
Anyway, it's weird that they are saying conversations kids aren't ready for when so many kids movies center on the death of a parent. IDK, I'd rather talk about gay people then about death to a small child.
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Páll Melsted @pmelsted.bsky.social · 06/03/2026
Excited to share this preprint that describes my latest work on using GPUs to accelerate processing of RNA-seq data. The title says it all: "RNA-seq analysis in seconds using GPUs" now on biorxiv www.biorxiv.org/content/10.6... and github github.com/pachterlab/k... Figure 1 shows they key result
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Tobias Schmidt @tpschmidt.com · 06/03/2026
Tool A gets compromised. Tool A installs Tool B. Tool B does whatever it wants. If you're running AI bots in CI/CD that touch secrets and process untrusted input (issues, PRs), you're one prompt away from full pipeline access 😅
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