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Páll Melsted

@pmelsted.bsky.social
1.6K followers 93 following 57 posts

Professor @hi.is in CS, head of rna seq data analysis at decode genetics (views are mine). Bioinformatician, epistemic trespasser, &c. ps. I hate GTF files

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Reposted by Páll Melsted
Nick Loman @pathogenomenick.bsky.social · 22/09/2026
Folks - if you're interested in how machine learning/AI can be used for microbial genomics, microbiome and metagenomics studies - please join us for a workshop in Birmingham on Thursday 8th October organised with CLIMB & NVIDIA. www.climb.ac.uk/blog/2026/09...
climb.ac.uk
Call for Applications: GPU-Accelerated Computing for Microbiome and Metagenomic Research · CLIMB
CLIMB is a cloud computing infrastructure for microbial bioinformatics — notebook servers, shared storage and reproducible workflows for genomics, metagenomics and pathogen surveillance researchers ac...
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Guillaume Holley @guillaumeolesan.bsky.social · 20/08/2026
I am delighted to present with @hannespetur.bsky.social our new study on the Icelandic pangenome reference HPRC-ICE. This work goes all the way from pangenome construction to disease association! (1/7) www.nature.com/articles/s41...
nature.com
An Icelandic pangenome reference - Nature
Newly developed methods enable construction of Icelandic haplotypes and mapping of population-scale short reads to a pangenome by reducing reference bias and improving discovery in low-mappability reg...
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Páll Melsted @pmelsted.bsky.social · 13/08/2026
It's hard to capture just how surreal the total eclipse was, even though it was cloudy. Darkness came instantly
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Reposted by Páll Melsted
Kristoffer Sahlin @ksahlin.bsky.social · 16/03/2026
𝗣𝗼𝘀𝘁𝗱𝗼𝗰 𝗮𝗻𝗱 𝗣𝗵𝗗 𝗽𝗼𝘀𝗶𝘁𝗶𝗼𝗻𝘀 𝗶𝗻 𝗖𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗚𝗲𝗻𝗼𝗺𝗶𝗰𝘀 / 𝗔𝗹𝗴𝗼𝗿𝗶𝘁𝗵𝗺𝗶𝗰 𝗕𝗶𝗼𝗶𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗰𝘀 I am currently recruiting for both: 🔹 Postdoc position su.varbi.com/what:job/job... 🔹 PhD position su.varbi.com/en/what:job/... Please share with anyone who might be interested!
su.varbi.com
Postdoktor i Beräkningsbiologi
Matematiska institutionen består av cirka 120 forskare, lärare och administrativ personal och är organiserad i tre huvudsakliga avdelningar: Matematik, Matematisk statistik och Beräkningsmatematik
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Páll Melsted @pmelsted.bsky.social · 06/03/2026
Excited to share this preprint that describes my latest work on using GPUs to accelerate processing of RNA-seq data. The title says it all: "RNA-seq analysis in seconds using GPUs" now on biorxiv www.biorxiv.org/content/10.6... and github github.com/pachterlab/k... Figure 1 shows they key result
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Páll Melsted @pmelsted.bsky.social · 22/02/2026
2015: growing almonds consumes too much energy and water 2026: growing kids consumes too much energy and eater bsky.app/profile/x2y....
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Páll Melsted @pmelsted.bsky.social · 10/01/2026
In pretty sure I’m thoroughly radiated after this
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Páll Melsted @pmelsted.bsky.social · 23/12/2025
Spotify wrap up is so last year
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Páll Melsted @pmelsted.bsky.social · 08/12/2025
14yo: I need a niche music recommendation Me: how about Godspeed You! Black Emperor, let’s find it *not found on Spotify* Me: That’s how nice they are
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Páll Melsted @pmelsted.bsky.social · 31/10/2025
Today I found out that the Pacbio tools for working with barcodes and adapters in Kinnex are called lima and skera. To whomever came up with that joke, I salute you, you’ve reached 50% of the audience
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Páll Melsted @pmelsted.bsky.social · 07/10/2025
All right, I posed this question to my PhD student this morning and he looked at me funny and asked if it was a trick question What is the running time of this code a, b = 0, 1 for _ in range(2, n+1): a, b = b, a + b return b
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Páll Melsted @pmelsted.bsky.social · 01/10/2025
Happy Q4 for those who celebrate
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Páll Melsted @pmelsted.bsky.social · 28/09/2025
Today I fixed a humming converter and an intercom receiver set from the 70’s. I’m surprised at how good ChatGPT is at diagnosing problems and coming up with fixes for hardware that is older than me. Since I didn’t have to replace the units I can justify the cost and environmental impact of AI
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Reposted by Páll Melsted
Ben Langmead @benlangmead.bsky.social · 22/08/2025
The Genome Informatics conference (@ Cold Spring Harbor Lab, Nov 5 - 8) abstract deadline is **today**. We welcome your submissions! Topics include: - PanGenomes - Genome Assembly & Seq. Algos. - Algorithmic Evo. Bio - Single Cell & Spatial Omics - Microbial Genomics - AI/ML & Integrative Omics 🙏🙏🙏
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Páll Melsted @pmelsted.bsky.social · 05/07/2025
Perfect marketing doesn’t exi…
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Páll Melsted @pmelsted.bsky.social · 27/06/2025
It is by the juice of coffee that thoughts acquire speed …
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Reposted by Páll Melsted
Oliver Stegle @oliverstegle.bsky.social · 26/06/2025
Job alert: Join us for a postdoc in AI in genetics at @EMBL Heidelberg! Great collaboration with @Adrian Cortes @GSK, aiming to develop new tools to elucidate genetic effects using population-scale cohorts and single-cell readouts. Please share! embl.wd103.myworkdayjobs.com/de-DE/EMBL/d...
embl.wd103.myworkdayjobs.com
Postdoctoral Researcher in Computational Genetics
The research group of Oliver Stegle looks for a postdoctoral researcher to join a collaborative project with GSK with the goal to apply computational methods to investigate the effects of rare variant...
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Páll Melsted @pmelsted.bsky.social · 24/06/2025
I misread that as “message” which would have been more impressive 🚩
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Reposted by Páll Melsted
Lior Pachter @lpachter.bsky.social · 03/06/2025
liorpachter.wordpress.com/2025/06/03/e...
liorpachter.wordpress.com
Epistemic failure of epistemic failure
Earlier this year I came across this interesting post by mathematician Daniel Litt, where he pondered how many intrinsically true results in mathematics have been published with erroneous proofs: D…
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Reposted by Páll Melsted
Jonathan Pritchard @jkpritch.bsky.social · 01/06/2025
I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required. Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
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Páll Melsted @pmelsted.bsky.social · 09/05/2025
In Iceland spring is not something you define as season based on weather but more from the arrival of migratory birds
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Páll Melsted @pmelsted.bsky.social · 05/05/2025
My favorite brainrot is an account on TikTok that solves complicated integrals on a blackboard with colored chalk.
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Páll Melsted @pmelsted.bsky.social · 30/04/2025
There is something refreshingly honest about moving the goalpost this blatantly. Adjusting for multiple testing? Not in my house ☝️
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Reposted by Páll Melsted
Erna Magnúsdóttir @e-rna.bsky.social · 22/04/2025
Join our lab to study transcriptional regulation in mouse germ cells and embryonic stem cells at @haskoliislands.bsky.social in beautiful Reykjavík! Apply here: tinyurl.com/34y6jcrd #epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
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Páll Melsted @pmelsted.bsky.social · 04/03/2025
Today I gave a lecture in a brand new lecture hall where the projector was acting weird. Turned out that the control panel showed green for when the projector was off, you had to press the button wait 10 seconds and then it turned red. I think this should be a case study in UI design
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Páll Melsted @pmelsted.bsky.social · 07/02/2025
I might need to replicate this paper www.nature.com/articles/s44...
nature.com
Periodic cooking of eggs - Communications Engineering
Emilia Di Lorenzo and colleagues propose an approach to address the energy transport problem of cooking the albumen and yolk of a boiled egg at their optimal temperatures without separation. By altern...
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Páll Melsted @pmelsted.bsky.social · 23/01/2025
Somehow I would be more confident that the Tesla could drive autonomously if the auto mode on the windshield wipers worked.
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Páll Melsted @pmelsted.bsky.social · 13/01/2025
Ironically this is the best content on that other place
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Páll Melsted @pmelsted.bsky.social · 05/01/2025
Beautiful polar stratospheric clouds today
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Páll Melsted @pmelsted.bsky.social · 05/12/2024
Productivity tip: set your phone to do not disturb, close all messaging software and email apps on your laptop, put on your headphones and Koyaanisqatsi on repeat. Don’t forget coffee.
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Páll Melsted @pmelsted.bsky.social · 22/11/2024
Let’s see if this bsky thing works. I have a 4K monitor at home and I want to connect a Mac mini and a Mac laptop to the monitor and external keyboard/mouse. Any recommendations on a KVM setup or favorite keyboard & mouse?
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Páll Melsted @pmelsted.bsky.social · 12/11/2024
Heading out to #genomeinformatics2024 remember to bring your adapters
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Páll Melsted @pmelsted.bsky.social · 05/11/2024
Today I almost obsessed over a piece of code that turns out took 7.6 seconds to run. Writing the code to measure the time took half a second, I just wrote a comment and cursor filled in the rest and I hit tab. Prior to AI I would have spent half an hour reading docs or stack overflow
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Reposted by Páll Melsted
Adam Phillippy @aphillippy.bsky.social · 28/11/2023
Reposting! This faculty search is open through December
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Páll Melsted @pmelsted.bsky.social · 05/11/2023
Adam Rutherford delivered a great overview of how the past of eugenics is still with us in today’s education of genetics and how it shapes the public view #ashg23 Fascinating to see the origin and paths of these ideas and phenotypes, accepted as truths (eye and hair color) even if they are false
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Páll Melsted @pmelsted.bsky.social · 02/11/2023
Robert Handsaker just delivered a mind blowing talk at #ashg23 Beautiful application of single cell omics to disentangle the expansion of CAG repeats to specific cell types in patients of Huntington’s disease
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Páll Melsted @pmelsted.bsky.social · 23/10/2023
I fought the linker and the linker won
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Páll Melsted @pmelsted.bsky.social · 01/10/2023
2017 vs 2023
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