Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 21/05/2026My Leibniz Healthtech lecture describing LASSO: www.youtube.com/watch?v=Ul7j...youtube.comLeibniz HealthTech Lecture: Dynamic Matrices (Elisha Krieg, IPF Dresden)YouTube video by Leibniz Health Technologies 011
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 17/06/2026Congrats again to shared first authors: Sarah Speed @jasperpeng.bsky.social @azratabye.bsky.social @anekoplato.bsky.social 👏👏👏👏 021
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 17/06/2026Thanks to Advanced Materials for selecting our article on "Olympic" gels for a cover! 🔗🔗🔗🔗🔗🔗🔗🔗🔗 advanced.onlinelibrary.wiley.com/doi/abs/10.1... #MaterialsScience #Biotechnology #Nanotechnology 173
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 04/08/2026Excited that the first #DyNAtrix 🧬 Pilot kits from @dynamicmatrices.bsky.social are now available at PELO Biotech GmbH General info: dynamicmatrices.eu/dynatrix/ Try the Ready-to-Use kit: www.pelobiotech.com/en/contact/?... Minimal Discovery kit: www.pelobiotech.com/en/contact/?... #CellCulture 032
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 06/08/20262/ Congrats to Yu-Hsuan Peng (@jasperpeng.bsky.social), Mathilde Lettinga, and Anna Taubenberger and for this important extension of the #DyNAtrix #3DCellCulture platform! Also, thanks to @marass.bsky.social for giving valuable feedback on the manuscript! #Mechanobiology #DNANanotechnology 021
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 06/08/2026How can we record the mechanical activity of cells in three dimensions? Our DNA force-history probes convert transient piconewton forces into persistent fluorescent signals, revealing spheroid activity, cellular protrusions, and migration tracks in a 3D matrix. www.biorxiv.org/content/10.6... 1167
Reposted by Krishna GuptaAzra Atabay @azratabye.bsky.social · 06/03/2026Working on this collaborative project in the Krieg lab has been a real pleasure. It began as a side ninja project with almost no budget but has grown and expanded so much. Really proud of what we have accomplished🥺 please check it out: advanced.onlinelibrary.wiley.com/doi/10.1002/...advanced.onlinelibrary.wiley.comAssembling a True “Olympic Gel” From over 16 000 Combinatorial DNA RingsOlympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and f... 032
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 06/03/2026This was a tour-de-force. Big congratulation to the whole team, in particular our FOUR outstanding first authors: Sarah Speed 🙏 Yu-Hsuan Peng @jasperpeng.bsky.social 🙏 Azra Atabay @azratabye.bsky.social 🙏 Krishna Gupta @anekoplato.bsky.social 🙏 9/11 112
Reposted by Krishna GuptaProf Ben Britton @bmatb.expmicromech.com · 18/09/2025This is doing the rounds in my messages with colleagues, and is a very real threat to the field of microscopy 😬. Given one (published) microscope image probably costs between $100 and $10,000 (or more) to make - the lure of "oh I will just ChatGPT it" is very much there. 1176
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 23/10/2025Multiplexed detection of viral pathogens on an AUTONOMOUSLY LOADING chip for point-of-care #diagnostics. Congrats to first authors Beatrise Berzina and Krishna Gupta and the entire EKFZ-funded *VirChip* team! 273
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 15/11/2025Big congrats to Dr. Krishna Gupta for winning the best poster prize at Oxford Global’s NextGen Omics conference in London, where he presented our work on #LASSO pulldown polymers. 💪 LASSO is a new general-purpose method for fast and ultra-selective biomolecule purification. 112
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 03/12/2025Thanks to Advanced Functional Materials for highlighting our work on their back cover! 223
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 19/12/2025If you're working with pulldown assays but suffer from their low capacity, low flexibility, sub-optimal specificity, carryover contaminations, and high cost, you may want to check out LASSO. Feel free to DM me if you're interested in testing it! 101
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 19/12/2025Just out in @angewandtechemie.bsky.social! #LASSO a new method for ultra-selective isolation of biomolecules (DNA, RNA, or protein). This method uses a unique polymer phase separation mechanism to gently capture and pull down specific target sequences. 132
Reposted by Krishna GuptaElisha Krieg @elishakrieg.bsky.social · 11/09/2025Exciting application of our programmable #CellCulture matrix #DyNAtrix. By creating a mechanically reconfigurable microenvironment, we can now invert & guide epithelial cell polarity in real time. #DNAnanotech 1/ 🧵 1124
